메뉴 건너뛰기




Volumn 8, Issue 10, 2012, Pages 3629-3642

Comparison of properties between NIPAAm-based simultaneously physically and chemically gelling polymer systems for use in vivo

Author keywords

Hydrogel; In situ gelling polymer system; Michael type addition reaction; Poly(NIPAAm); Thermoresponsive

Indexed keywords

ADDITION REACTIONS; CROSSLINKING; DEGRADATION; ELASTIC MODULI; GELS; HYDROGELS; REACTION RATES; SCANNING ELECTRON MICROSCOPY;

EID: 84865516851     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.06.012     Document Type: Article
Times cited : (26)

References (55)
  • 1
    • 36549073613 scopus 로고    scopus 로고
    • Thermoresponsive hydrogels in biomedical applications
    • L. Klouda, and A.G. Mikos Thermoresponsive hydrogels in biomedical applications Eur J Pharm Biopharm 68 2008 34 45
    • (2008) Eur J Pharm Biopharm , vol.68 , pp. 34-45
    • Klouda, L.1    Mikos, A.G.2
  • 2
    • 84924991730 scopus 로고
    • Solution properties of poly (N-isopropylacrylamide)
    • M. Heskins, and J.E. Guillet Solution properties of poly (N-isopropylacrylamide) J Macromol Sci Chem 2 1968 1441 1455
    • (1968) J Macromol Sci Chem , vol.2 , pp. 1441-1455
    • Heskins, M.1    Guillet, J.E.2
  • 3
    • 0027591475 scopus 로고
    • Effect of comonomer hydrophilicity and ionization on the lower critical solution temperature of N-isopropylacrylamide copolymers
    • H. Feil, Y.H. Bae, J. Feijen, and S.W. Kim Effect of comonomer hydrophilicity and ionization on the lower critical solution temperature of N-isopropylacrylamide copolymers Macromolecules 26 1993 2496 2500
    • (1993) Macromolecules , vol.26 , pp. 2496-2500
    • Feil, H.1    Bae, Y.H.2    Feijen, J.3    Kim, S.W.4
  • 4
    • 0033517611 scopus 로고    scopus 로고
    • Synthesis and characterization of injectable poly (N-isopropylacrylamide) -based hydrogels that support tissue formation in vitro
    • R.A. Stile, W.R. Burghardt, and K.E. Healy Synthesis and characterization of injectable poly (N-isopropylacrylamide)-based hydrogels that support tissue formation in vitro Macromolecules 32 1999 7370 7379
    • (1999) Macromolecules , vol.32 , pp. 7370-7379
    • Stile, R.A.1    Burghardt, W.R.2    Healy, K.E.3
  • 5
    • 0033486426 scopus 로고    scopus 로고
    • Lower critical solution temperatures of N-substituted acrylamide copolymers in aqueous solutions
    • H.Y. Liu, and X.X. Zhu Lower critical solution temperatures of N-substituted acrylamide copolymers in aqueous solutions Polymer 40 1999 6985 6990
    • (1999) Polymer , vol.40 , pp. 6985-6990
    • Liu, H.Y.1    Zhu, X.X.2
  • 6
    • 32344452111 scopus 로고    scopus 로고
    • Development of a temperature-sensitive composite hydrogel for drug delivery applications
    • R.M.K. Ramanan, P. Chellamuthu, L. Tang, and K.T. Nguyen Development of a temperature-sensitive composite hydrogel for drug delivery applications Biotechnol Prog 22 2006 118 125
    • (2006) Biotechnol Prog , vol.22 , pp. 118-125
    • Ramanan, R.M.K.1    Chellamuthu, P.2    Tang, L.3    Nguyen, K.T.4
  • 7
    • 34247573414 scopus 로고    scopus 로고
    • Functional copolymers of N-isopropylacrylamide for bioengineering applications
    • Z.M.O. Rzaev, S. Diner, and E. Piskin Functional copolymers of N-isopropylacrylamide for bioengineering applications Prog Polym Sci 32 2007 534 595
    • (2007) Prog Polym Sci , vol.32 , pp. 534-595
    • Rzaev, Z.M.O.1    Diner, S.2    Piskin, E.3
  • 8
    • 79953785904 scopus 로고    scopus 로고
    • Synthesis, characterization and properties of a physically and chemically gelling polymer system using poly (NIPAAm-co-HEMA-acrylate) and poly (NIPAAm-co-cysteamine)
    • H.H. Bearat, B.H. Lee, J. Valdez, and B.L. Vernon Synthesis, characterization and properties of a physically and chemically gelling polymer system using poly (NIPAAm-co-HEMA-acrylate) and poly (NIPAAm-co-cysteamine) J Biomater Sci Polym Ed 22 2011 1299 1318
    • (2011) J Biomater Sci Polym Ed , vol.22 , pp. 1299-1318
    • Bearat, H.H.1    Lee, B.H.2    Valdez, J.3    Vernon, B.L.4
  • 9
    • 0012359854 scopus 로고    scopus 로고
    • Temperature and pH dependent solubility of novel poly (N-isopropylacrylamide)-copolymers
    • D. Kuckling, H.J.P. Adler, K.F. Arndt, L. Ling, and W.D. Habicher Temperature and pH dependent solubility of novel poly (N-isopropylacrylamide)- copolymers Macromol Chem Phys 201 2000 273 280
    • (2000) Macromol Chem Phys , vol.201 , pp. 273-280
    • Kuckling, D.1    Adler, H.J.P.2    Arndt, K.F.3    Ling, L.4    Habicher, W.D.5
  • 10
    • 0032319131 scopus 로고    scopus 로고
    • Rheological characterisation of polymer gels
    • G.M. Kavanagh, and S.B. Ross-Murphy Rheological characterisation of polymer gels Prog Polym Sci 23 1998 533 562
    • (1998) Prog Polym Sci , vol.23 , pp. 533-562
    • Kavanagh, G.M.1    Ross-Murphy, S.B.2
  • 11
    • 0037122675 scopus 로고    scopus 로고
    • Hydrogels for biomedical applications
    • A.S. Hoffman Hydrogels for biomedical applications Adv Drug Delivery Rev 54 2002 3 12
    • (2002) Adv Drug Delivery Rev , vol.54 , pp. 3-12
    • Hoffman, A.S.1
  • 12
    • 0027108539 scopus 로고
    • Viscoelastic properties of physically crosslinked networks. 1. Transient network theory
    • F. Tanaka, and S. Edwards Viscoelastic properties of physically crosslinked networks. 1. Transient network theory Macromolecules 25 1992 1516 1523
    • (1992) Macromolecules , vol.25 , pp. 1516-1523
    • Tanaka, F.1    Edwards, S.2
  • 13
    • 33646679654 scopus 로고    scopus 로고
    • Michael addition reactions in macromolecular design for emerging technologies
    • B.D. Mather, K. Viswanathan, K.M. Miller, and T.E. Long Michael addition reactions in macromolecular design for emerging technologies Prog Polym Sci 31 2006 487 531
    • (2006) Prog Polym Sci , vol.31 , pp. 487-531
    • Mather, B.D.1    Viswanathan, K.2    Miller, K.M.3    Long, T.E.4
  • 14
    • 0038516829 scopus 로고    scopus 로고
    • Synthesis and physicochemical characterization of end-linked poly (ethylene glycol)-co-peptide hydrogels formed by Michael-type addition
    • M. Lutolf, and J. Hubbell Synthesis and physicochemical characterization of end-linked poly (ethylene glycol)-co-peptide hydrogels formed by Michael-type addition Biomacromolecules 4 2003 713 722
    • (2003) Biomacromolecules , vol.4 , pp. 713-722
    • Lutolf, M.1    Hubbell, J.2
  • 15
    • 0035811971 scopus 로고    scopus 로고
    • Rigid, thermosetting liquid molding resins from renewable resources. I. Synthesis and polymerization of soy oil monoglyceride maleates
    • E. Can, S. Küsefolu, and R. Wool Rigid, thermosetting liquid molding resins from renewable resources. I. Synthesis and polymerization of soy oil monoglyceride maleates J Appl Polym Sci 81 2001 69 77
    • (2001) J Appl Polym Sci , vol.81 , pp. 69-77
    • Can, E.1    Küsefolu, S.2    Wool, R.3
  • 16
    • 52049090797 scopus 로고    scopus 로고
    • Protein adsorption and cell adhesion on nanoscale bioactive coatings formed from poly (ethylene glycol) and albumin microgels
    • E.A. Scott, M.D. Nichols, L.H. Cordova, B.J. George, Y.S. Jun, and D.L. Elbert Protein adsorption and cell adhesion on nanoscale bioactive coatings formed from poly (ethylene glycol) and albumin microgels Biomaterials 29 2008 4481 4493
    • (2008) Biomaterials , vol.29 , pp. 4481-4493
    • Scott, E.A.1    Nichols, M.D.2    Cordova, L.H.3    George, B.J.4    Jun, Y.S.5    Elbert, D.L.6
  • 17
    • 77955778221 scopus 로고    scopus 로고
    • In situ forming hydrogels by tandem thermal gelling and Michael addition reaction between thermosensitive triblock copolymers and thiolated hyaluronan
    • R. Censi, P.J. Fieten, P. di Martino, W.E. Hennink, and T. Vermonden In situ forming hydrogels by tandem thermal gelling and Michael addition reaction between thermosensitive triblock copolymers and thiolated hyaluronan Macromolecules 43 2010 5771 5778
    • (2010) Macromolecules , vol.43 , pp. 5771-5778
    • Censi, R.1    Fieten, P.J.2    Di Martino, P.3    Hennink, W.E.4    Vermonden, T.5
  • 18
    • 1942486842 scopus 로고    scopus 로고
    • Towards a fully-synthetic substitute of alginate: Development of a new process using thermal gelation and chemical cross-linking
    • F. Cellesi, N. Tirelli, and J.A. Hubbell Towards a fully-synthetic substitute of alginate: development of a new process using thermal gelation and chemical cross-linking Biomaterials 25 2004 5115 5124
    • (2004) Biomaterials , vol.25 , pp. 5115-5124
    • Cellesi, F.1    Tirelli, N.2    Hubbell, J.A.3
  • 19
    • 46849118467 scopus 로고    scopus 로고
    • Synthesis and characterization of injectable, thermally and chemically gelable, amphiphilic poly (N-isopropylacrylamide)-based macromers
    • M.C. Hacker, L. Klouda, B.B. Ma, J.D. Kretlow, and A.G. Mikos Synthesis and characterization of injectable, thermally and chemically gelable, amphiphilic poly (N-isopropylacrylamide)-based macromers Biomacromolecules 9 2008 1558 1570
    • (2008) Biomacromolecules , vol.9 , pp. 1558-1570
    • Hacker, M.C.1    Klouda, L.2    Ma, B.B.3    Kretlow, J.D.4    Mikos, A.G.5
  • 20
    • 77956460936 scopus 로고    scopus 로고
    • Thermosensitive in situ-forming dextran-pluronic hydrogels through Michael addition
    • C. Lin, P. Zhao, F. Li, F. Guo, Z. Li, and X. Wen Thermosensitive in situ-forming dextran-pluronic hydrogels through Michael addition Mater Sci Eng C 30 2010 1236 1244
    • (2010) Mater Sci Eng C , vol.30 , pp. 1236-1244
    • Lin, C.1    Zhao, P.2    Li, F.3    Guo, F.4    Li, Z.5    Wen, X.6
  • 21
    • 0000189906 scopus 로고
    • Relative nucleophilic reactivities of amino groups and mercaptide ions in addition reactions with α, β-unsaturated compounds1, 2
    • M. Friedman, J. Cavins, and J. Wall Relative nucleophilic reactivities of amino groups and mercaptide ions in addition reactions with α, β-unsaturated compounds1, 2 J Am Chem Soc 87 1965 3672 3682
    • (1965) J Am Chem Soc , vol.87 , pp. 3672-3682
    • Friedman, M.1    Cavins, J.2    Wall, J.3
  • 23
    • 23344449409 scopus 로고    scopus 로고
    • Studies on preparation and properties of NIPAAm/hydrophobic monomer copolymeric hydrogels
    • W.F. Lee, and Y.C. Yeh Studies on preparation and properties of NIPAAm/hydrophobic monomer copolymeric hydrogels Eur Polym J 41 2005 2488 2495
    • (2005) Eur Polym J , vol.41 , pp. 2488-2495
    • Lee, W.F.1    Yeh, Y.C.2
  • 24
    • 0037122786 scopus 로고    scopus 로고
    • Thermosensitive sol-gel reversible hydrogels
    • B. Jeong, S.W. Kim, and Y.H. Bae Thermosensitive sol-gel reversible hydrogels Adv Drug Delivery Rev 54 2002 37 51
    • (2002) Adv Drug Delivery Rev , vol.54 , pp. 37-51
    • Jeong, B.1    Kim, S.W.2    Bae, Y.H.3
  • 25
    • 0036629185 scopus 로고    scopus 로고
    • Lessons from nature: Stimuli-responsive polymers and their biomedical applications
    • B. Jeong, and A. Gutowska Lessons from nature: stimuli-responsive polymers and their biomedical applications Trends Biotechnol 20 2002 305 311
    • (2002) Trends Biotechnol , vol.20 , pp. 305-311
    • Jeong, B.1    Gutowska, A.2
  • 26
    • 0030033719 scopus 로고    scopus 로고
    • Mechanisms of polymer degradation and erosion
    • A. Gopferich Mechanisms of polymer degradation and erosion Biomaterials 17 1996 103 114
    • (1996) Biomaterials , vol.17 , pp. 103-114
    • Gopferich, A.1
  • 27
    • 33947474357 scopus 로고
    • Hydroxyl Group Catalysis. III. 1 the nature of neighboring hydroxyl group assistance in the alkaline hydrolysis of the ester bond
    • T.C. Bruice, and T.H. Fife Hydroxyl Group Catalysis. III. 1 The nature of neighboring hydroxyl group assistance in the alkaline hydrolysis of the ester bond J Am Chem Soc 84 1962 1973 1979
    • (1962) J Am Chem Soc , vol.84 , pp. 1973-1979
    • Bruice, T.C.1    Fife, T.H.2
  • 28
    • 34247637887 scopus 로고    scopus 로고
    • New hydrolysis-dependent thermosensitive polymer for an injectable degradable system
    • Z. Cui, B.H. Lee, and B.L. Vernon New hydrolysis-dependent thermosensitive polymer for an injectable degradable system Biomacromolecules 8 2007 1280 1286
    • (2007) Biomacromolecules , vol.8 , pp. 1280-1286
    • Cui, Z.1    Lee, B.H.2    Vernon, B.L.3
  • 29
    • 49749177569 scopus 로고
    • A colorimetric method for determining low concentrations of mercaptans
    • G.L. Ellman A colorimetric method for determining low concentrations of mercaptans Arch Biochem Biophys 74 1958 443 450
    • (1958) Arch Biochem Biophys , vol.74 , pp. 443-450
    • Ellman, G.L.1
  • 30
    • 0033360915 scopus 로고    scopus 로고
    • A reexamination of the angiotoxicity of superselective injection of DMSO in the swine rete embolization model
    • J.C. Chaloupka, D.C. Huddle, J. Alderman, S. Fink, R. Hammond, and H.V. Vinters A reexamination of the angiotoxicity of superselective injection of DMSO in the swine rete embolization model Am J Neuroradiol 20 1999 401 410
    • (1999) Am J Neuroradiol , vol.20 , pp. 401-410
    • Chaloupka, J.C.1    Huddle, D.C.2    Alderman, J.3    Fink, S.4    Hammond, R.5    Vinters, H.V.6
  • 31
    • 33749680748 scopus 로고    scopus 로고
    • Organic solvents as vehicles for precipitating liquid embolics: A comparative angiotoxicity study with superselective injections of swine rete mirabile
    • O. Dudeck Organic solvents as vehicles for precipitating liquid embolics: a comparative angiotoxicity study with superselective injections of swine rete mirabile Am J Neuroradiol 27 2006 1900 1906
    • (2006) Am J Neuroradiol , vol.27 , pp. 1900-1906
    • Dudeck, O.1
  • 32
    • 0345164356 scopus 로고    scopus 로고
    • Nonadhesive liquid embolic agent for cerebral arteriovenous malformations: Preliminary histopathological studies in swine rete mirabile
    • Y. Murayama Nonadhesive liquid embolic agent for cerebral arteriovenous malformations: preliminary histopathological studies in swine rete mirabile Neurosurgery 43 1998 1164 1175
    • (1998) Neurosurgery , vol.43 , pp. 1164-1175
    • Murayama, Y.1
  • 33
    • 3843071010 scopus 로고    scopus 로고
    • In situ-forming hydrogels - Review of temperature-sensitive systems
    • E. Ruel-Gariepy, and J.C. Leroux In situ-forming hydrogels - review of temperature-sensitive systems Eur J Pharm Biopharm 58 2004 409 426
    • (2004) Eur J Pharm Biopharm , vol.58 , pp. 409-426
    • Ruel-Gariepy, E.1    Leroux, J.C.2
  • 34
    • 1342281026 scopus 로고    scopus 로고
    • MMP-2 sensitive, VEGF-bearing bioactive hydrogels for promotion of vascular healing
    • D. Seliktar, A. Zisch, M. Lutolf, J. Wrana, and J. Hubbell MMP-2 sensitive, VEGF-bearing bioactive hydrogels for promotion of vascular healing J Biomed Mater Res A 68 2004 704 716
    • (2004) J Biomed Mater Res A , vol.68 , pp. 704-716
    • Seliktar, D.1    Zisch, A.2    Lutolf, M.3    Wrana, J.4    Hubbell, J.5
  • 36
    • 33644631799 scopus 로고    scopus 로고
    • Gel strength and solution viscosity of temperature-sensitive, in-situ-gelling polymers for endovascular embolization
    • B. Vernon, and A. Martinez Gel strength and solution viscosity of temperature-sensitive, in-situ-gelling polymers for endovascular embolization J Biomater Sci Polym Ed 16 2005 1153 1166
    • (2005) J Biomater Sci Polym Ed , vol.16 , pp. 1153-1166
    • Vernon, B.1    Martinez, A.2
  • 37
    • 0029403702 scopus 로고
    • Synthesis and characterization of thermo- and chemomechanically responsive poly (N-isopropylacrylamide-co-methacrylic acid) hydrogels
    • C.S. Brazel, and N.A. Peppas Synthesis and characterization of thermo- and chemomechanically responsive poly (N-isopropylacrylamide-co-methacrylic acid) hydrogels Macromolecules 28 1995 8016 8020
    • (1995) Macromolecules , vol.28 , pp. 8016-8020
    • Brazel, C.S.1    Peppas, N.A.2
  • 38
    • 4243656934 scopus 로고
    • Microcalorimetric detection of lower critical solution temperatures in aqueous polymer solutions
    • H.G. Schild, and D.A. Tirrell Microcalorimetric detection of lower critical solution temperatures in aqueous polymer solutions J Phys Chem 94 1990 4352 4356
    • (1990) J Phys Chem , vol.94 , pp. 4352-4356
    • Schild, H.G.1    Tirrell, D.A.2
  • 39
    • 0025848887 scopus 로고
    • "on-off" thermocontrol of solute transport. I. Temperature dependence of swelling of N-isopropylacrylamide networks modified with hydrophobic components in water
    • Y.H. Bae, T. Okano, and S.W. Kim "On-off" thermocontrol of solute transport. I. Temperature dependence of swelling of N-isopropylacrylamide networks modified with hydrophobic components in water Pharm Res 8 1991 531 537
    • (1991) Pharm Res , vol.8 , pp. 531-537
    • Bae, Y.H.1    Okano, T.2    Kim, S.W.3
  • 40
    • 34249866545 scopus 로고    scopus 로고
    • Rapidly in situ-forming degradable hydrogels from dextran thiols through Michael addition
    • C. Hiemstra, L.J. van der Aa, Z. Zhong, P.J. Dijkstra, and J. Feijen Rapidly in situ-forming degradable hydrogels from dextran thiols through Michael addition Biomacromolecules 8 2007 1548 1556
    • (2007) Biomacromolecules , vol.8 , pp. 1548-1556
    • Hiemstra, C.1    Van Der Aa, L.J.2    Zhong, Z.3    Dijkstra, P.J.4    Feijen, J.5
  • 41
    • 0035981078 scopus 로고    scopus 로고
    • Environment-sensitive hydrogels for drug delivery
    • Y. Qiu, and K. Park Environment-sensitive hydrogels for drug delivery Adv Drug Delivery Rev 53 2001 321 339
    • (2001) Adv Drug Delivery Rev , vol.53 , pp. 321-339
    • Qiu, Y.1    Park, K.2
  • 43
    • 0026928194 scopus 로고
    • Mutual influence of pH and temperature on the swelling of ionizable and thermosensitive hydrogels
    • H. Feil, Y. Bae, J. Feijen, and S. Kim Mutual influence of pH and temperature on the swelling of ionizable and thermosensitive hydrogels Macromolecules 25 1992 5528 5530
    • (1992) Macromolecules , vol.25 , pp. 5528-5530
    • Feil, H.1    Bae, Y.2    Feijen, J.3    Kim, S.4
  • 44
    • 0037941099 scopus 로고    scopus 로고
    • Synthesis of fast-swelling superabsorbent hydrogels: Effect of crosslinker type and concentration on porosity and absorption rate
    • K. Kabiri, H. Omidian, S. Hashemi, and M. Zohuriaan-Mehr Synthesis of fast-swelling superabsorbent hydrogels: effect of crosslinker type and concentration on porosity and absorption rate Eur Polym J 39 2003 1341 1348
    • (2003) Eur Polym J , vol.39 , pp. 1341-1348
    • Kabiri, K.1    Omidian, H.2    Hashemi, S.3    Zohuriaan-Mehr, M.4
  • 45
    • 0842285531 scopus 로고    scopus 로고
    • Structure and swelling of poly (acrylic acid) hydrogels: Effect of pH, ionic strength, and dilution on the crosslinked polymer structure
    • J.E. Elliott, M. Macdonald, J. Nie, and C.N. Bowman Structure and swelling of poly (acrylic acid) hydrogels: effect of pH, ionic strength, and dilution on the crosslinked polymer structure Polymer 45 2004 1503 1510
    • (2004) Polymer , vol.45 , pp. 1503-1510
    • Elliott, J.E.1    MacDonald, M.2    Nie, J.3    Bowman, C.N.4
  • 46
    • 0025789505 scopus 로고
    • Equilibrium swelling behavior of pH-sensitive hydrogels
    • L. Brannon-Peppas, and N.A. Peppas Equilibrium swelling behavior of pH-sensitive hydrogels Chem Eng Sci 46 1991 715 722
    • (1991) Chem Eng Sci , vol.46 , pp. 715-722
    • Brannon-Peppas, L.1    Peppas, N.A.2
  • 47
    • 33745610186 scopus 로고    scopus 로고
    • In-situ injectable physically and chemically gelling NIPAAm-based copolymer system for embolization
    • B.H. Lee, B. West, R. McLemore, C. Pauken, and B.L. Vernon In-situ injectable physically and chemically gelling NIPAAm-based copolymer system for embolization Biomacromolecules 7 2006 2059 2064
    • (2006) Biomacromolecules , vol.7 , pp. 2059-2064
    • Lee, B.H.1    West, B.2    McLemore, R.3    Pauken, C.4    Vernon, B.L.5
  • 48
    • 34547129075 scopus 로고    scopus 로고
    • Simultaneously physically and chemically gelling polymer system utilizing a poly (NIPAAm-co-cysteamine)-based copolymer
    • S.A. Robb, B.H. Lee, R. McLemore, and B.L. Vernon Simultaneously physically and chemically gelling polymer system utilizing a poly (NIPAAm-co-cysteamine)-based copolymer Biomacromolecules 8 2007 2294 2300
    • (2007) Biomacromolecules , vol.8 , pp. 2294-2300
    • Robb, S.A.1    Lee, B.H.2    McLemore, R.3    Vernon, B.L.4
  • 49
    • 0037465483 scopus 로고    scopus 로고
    • Wide-range control of deswelling time for thermosensitive poly (N-isopropylacrylamide) gel treated by freeze-drying
    • N. Kato, Y. Sakai, and S. Shibata Wide-range control of deswelling time for thermosensitive poly (N-isopropylacrylamide) gel treated by freeze-drying Macromolecules 36 2003 961 963
    • (2003) Macromolecules , vol.36 , pp. 961-963
    • Kato, N.1    Sakai, Y.2    Shibata, S.3
  • 50
    • 0035385135 scopus 로고    scopus 로고
    • Hydrogels for tissue engineering
    • K.Y. Lee, and D.J. Mooney Hydrogels for tissue engineering Chem Rev 101 2001 1869 1880
    • (2001) Chem Rev , vol.101 , pp. 1869-1880
    • Lee, K.Y.1    Mooney, D.J.2
  • 51
    • 68149170558 scopus 로고    scopus 로고
    • Cytotoxic evaluation of N-isopropylacrylamide monomers and temperature-sensitive poly (N-isopropylacrylamide) nanoparticles
    • A.S. Wadajkar, B. Koppolu, M. Rahimi, and K.T. Nguyen Cytotoxic evaluation of N-isopropylacrylamide monomers and temperature-sensitive poly (N-isopropylacrylamide) nanoparticles J Nanopart Res 11 2009 1375 1382
    • (2009) J Nanopart Res , vol.11 , pp. 1375-1382
    • Wadajkar, A.S.1    Koppolu, B.2    Rahimi, M.3    Nguyen, K.T.4
  • 52
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Methods 65 1983 55 63
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 53
    • 3542992074 scopus 로고    scopus 로고
    • Surface modified superparamagnetic nanoparticles for drug delivery: Interaction studies with human fibroblasts in culture
    • A.K. Gupta, and A.S.G. Curtis Surface modified superparamagnetic nanoparticles for drug delivery: interaction studies with human fibroblasts in culture J Mater Sci Mater Med 15 2004 493 496
    • (2004) J Mater Sci Mater Med , vol.15 , pp. 493-496
    • Gupta, A.K.1    Curtis, A.S.G.2
  • 54
    • 77952164642 scopus 로고    scopus 로고
    • Manipulating degradation time in a N-isopropylacrylamide-based co-polymer with hydrolysis-dependent LCST
    • Z. Cui, B.H. Lee, C. Pauken, and B.L. Vernon Manipulating degradation time in a N-isopropylacrylamide-based co-polymer with hydrolysis-dependent LCST J Biomater Sci Polym Ed 6 2010 913 926
    • (2010) J Biomater Sci Polym Ed , vol.6 , pp. 913-926
    • Cui, Z.1    Lee, B.H.2    Pauken, C.3    Vernon, B.L.4
  • 55
    • 34548535410 scopus 로고    scopus 로고
    • Poly (N-isopropylacrylamide-co-poly (ethylene glycol))-acrylate simultaneously physically and chemically gelling polymer systems
    • V. Cheng, B.H. Lee, C. Pauken, and B.L. Vernon Poly (N- isopropylacrylamide-co-poly (ethylene glycol))-acrylate simultaneously physically and chemically gelling polymer systems J Appl Polym Sci 106 2007 1201 1207
    • (2007) J Appl Polym Sci , vol.106 , pp. 1201-1207
    • Cheng, V.1    Lee, B.H.2    Pauken, C.3    Vernon, B.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.