The relationship between brain volume and walking outcomes in older adults with and without diabetic peripheral neuropathy

Diabetes Care

Volumn 35, Issue 9, 2012, Pages 1907-1912

  Manor, Brad ^a,b   Abduljalil, Amir ^d   Newton, Elizabeth ^b,c   Novak, Vera ^a,b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Hebrew Senior Life   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BASAL GANGLION; BRAIN SIZE; CEREBELLUM; CONTROLLED STUDY; DIABETIC NEUROPATHY; FEMALE; GRAY MATTER; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEAR MAGNETIC RESONANCE IMAGING; PREFRONTAL CORTEX; PRESSURE SENSATION; WALKING; WALKING SPEED;

AGED; AGED, 80 AND OVER; BRAIN; DIABETIC NEUROPATHIES; FEMALE; HUMANS; MALE; MIDDLE AGED; WALKING;

EID: 84865511360     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc11-2463     Document Type: Article

References (34)

1. Candrilli SD, Davis KL, Kan HJ, Lucero MA, Rousculp MD. Prevalence and the associated burden of illness of symptoms of diabetic peripheral neuropathy and diabetic retinopathy. J Diabetes Complications 2007;21:306-314
2. Gregg EW, Sorlie P, Paulose-RamR, et al.; 1999-2000 national health and nutrition examination survey. Prevalence of lower-extremity disease in the US adult population >=40 years of age with and without diabetes: 1999-2000 national health and nutrition examination survey. Diabetes Care 2004;27:1591-1597
3. Menz HB, Lord SR, St George R, Fitzpatrick RC. Walking stability and sensorimotor function in older people with diabetic peripheral neuropathy. Arch Phys Med Rehabil 2004;85:245-252
4. Manor B, Wolenski P, Li L. Faster walking speeds increase local instability among people with peripheral neuropathy. J Biomech 2008;41:2787-2792
5. Studenski S, Perera S, Patel K, et al. Gait speed and survival in older adults. JAMA 2011;305:50-58
6. Abellan van Kan G, Rolland Y, Andrieu S, et al.Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force. J Nutr Health Aging 2009;13:881-889
7. Black FO, Paloski WH, Doxey-Gasway DD, Reschke MF. Vestibular plasticity following orbital spaceflight: recovery from postflight postural instability. Acta Otolaryngol Suppl 1995;520:450-454
8. Kloter E, Wirz M, Dietz V. Locomotion in stroke subjects: interactions between unaffected and affected sides. Brain 2011;134:721-731
9. Manor B, Hu K, Zhao P, et al. Altered control of postural sway following cerebral infarction: a cross-sectional analysis. Neurology 2010;74:458-464
10. Perez NI, Rama JI, Martinez Vila E. Vision preference in dynamic posturography analysed according to vestibular impairment and handicap. Rev Laryngol Otol Rhinol (Bord) 2004;125:215-221
11. Manor B, Costa MD, Hu K, et al. Physiological complexity and system adaptability: evidence from postural control dynamics of older adults. J Appl Physiol 2010;109:1786-1791
12. Rosano C, Aizenstein HJ, Studenski S, Newman AB. A regions-of-interest volumetric analysis of mobility limitations in community-dwelling older adults. J Gerontol A Biol Sci Med Sci 2007;62:1048-1055
13. Rosano C, Brach J, Studenski S, Longstreth WT Jr, Newman AB. Gait variability is associated with subclinical brain vascular abnormalities in high-functioning older adults. Neuroepidemiology 2007;29:193-200
14. Feng Y, Schlösser FJ, Sumpio BE. The Semmes Weinstein monofilament examination as a screening tool for diabetic peripheral neuropathy. J Vasc Surg 2009;50:675-682
15. Kamei N, Yamane K, Nakanishi S, et al. Effectiveness of Semmes-Weinstein monofilament examination for diabetic peripheral neuropathy screening. J Diabetes Complications 2005;19:47-53
16. Bril V, Perkins BA. Validation of the Toronto Clinical Scoring System for diabetic polyneuropathy. Diabetes Care 2002;25:2048-2052
17. Shattuck DW, Mirza M, Adisetiyo V, et al. Construction of a 3D probabilistic atlas of human cortical structures. Neuroimage 2008;39:1064-1080
18. Benson RR, Guttmann CR, Wei X, et al. Older people with impaired mobility have specific loci of periventricular abnormality on MRI. Neurology 2002;58:48-55
19. Rosano C, Aizenstein H, Brach J, Longenberger A, Studenski S, Newman AB. Special article: gait measures indicate underlying focal gray matter atrophy in the brain of older adults. J Gerontol A Biol Sci Med Sci 2008;63:1380-1388
20. Viccaro LJ, Perera S, Studenski SA. Is timed up and go better than gait speed in predicting health, function, and falls in older adults? J Am Geriatr Soc 2011;59:887-892
21. Strotmeyer ES, de Rekeneire N, Schwartz AV, et al. The relationship of reduced peripheral nerve function and diabetes with physical performance in older white and black adults: the Health, Aging, and Body Composition (Health ABC) study. Diabetes Care 2008;31:1767-1772
22. Giacomozzi C, Caselli A, Macellari V, Giurato L, Lardieri L, Uccioli L. Walking strategy in diabetic patients with peripheral neuropathy. Diabetes Care 2002;25:1451-1457
23. Manor B, Li L. Characteristics of functional gait among people with and without peripheral neuropathy. Gait Posture 2009;30:253-256
24. Richardson JK, Ashton-Miller JA. Peripheral neuropathy: an often-overlooked cause of falls in the elderly. Postgrad Med 1996;99:161-172
25. Richardson JK, Thies SB, DeMott TK, Ashton-Miller JA. A comparison of gait characteristics between older women with and without peripheral neuropathy in standard and challenging environments. J Am Geriatr Soc 2004;52:1532-1537
26. Volpato S, Blaum C, Resnick H, Ferrucci L, Fried LP, Guralnik JM;Women's Health and Aging Study. Comorbidities and impairments explaining the association between diabetes and lower extremity disability: The Women's Health and Aging Study. Diabetes Care 2002;25:678-683
27. Chastan N, Westby GW, Yelnik J, et al. Effects of nigral stimulation on locomotion and postural stability in patients with Parkinson's disease. Brain 2009;132:172-184
28. Ilg W, Giese MA, Gizewski ER, Schoch B, Timmann D. The influence of focal cerebellar lesions on the control and adaptation of gait. Brain 2008;131:2913-2927
29. Takezawa N, Mizuno T, Seo K, Kondo M, Nakagawa M. Gait disturbances related to dysfunction of the cerebral cortex and basal ganglia. Brain Nerve 2010;62:1193-1202 [in Japanese]
30. Yogev-Seligmann G, Hausdorff JM, Giladi N. The role of executive function and attention in gait. Mov Disord 2008;23:329-342
31. Crenna P, Carpinella I, Lopiano L, et al. Influence of basal ganglia on upper limb locomotor synergies. Evidence from deep brain stimulation and L-DOPA treatment in Parkinson's disease. Brain 2008;131:3410-3420
32. Kane MJ, Engle RW. The role of prefrontal cortex in working-memory capacity, executive attention, and general fluid intelligence: an individual-differences perspective. Psychon Bull Rev 2002;9:637-671
33. Paul L, Ellis BM, Leese GP, McFadyen AK, McMurray B. The effect of a cognitive or motor task on gait parameters of diabetic patients, with and without neuropathy. Diabet Med 2009;26:234-239
34. Leveille SG, Jones RN, Kiely DK, et al. Chronic musculoskeletal pain and the occurrence of falls in an older population. JAMA 2009;302:2214-2221