A novel aminopeptidase N inhibitor developed by virtual screening approach

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 18, 2012, Pages 5863-5869

  Feng, Jinhong ^a,b   Jin, Kang ^b   Zhu, Huawei ^b   Zhang, Xiaopan ^b   Zhang, Lei ^b   Liu, Jianhua ^a   Xu, Wenfang ^b  

^a QILU UNIVERSITY OF TECHNOLOGY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Aminopeptidase N inhibitors; Antitumor; Cell invasion; Docking; Virtual screening

Indexed keywords

BESTATIN; HYDROLASE INHIBITOR; ZINC;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DRUG BINDING; DRUG INHIBITION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; ENZYME ASSAY; ENZYME INHIBITION ASSAY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PHARMACOPHORE; SCREENING; VIRTUAL SCREENING;

ANIMALS; ANTIGENS, CD13; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HIGH-THROUGHPUT SCREENING ASSAYS; HL-60 CELLS; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84865501560     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.07.086     Document Type: Article

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