Nebulized hypertonic saline attenuates acute lung injury following trauma and hemorrhagic shock via inhibition of matrix metalloproteinase-13

Critical Care Medicine

Volumn 40, Issue 9, 2012, Pages 2647-2653

  Wohlauer, Max ^a   Moore, Ernest E ^a,b   Silliman, Christopher C ^a,c   Fragoso, Miguel ^a   Gamboni, Fabia ^a   Harr, Jeffrey ^a   Accurso, Frank ^a   Wright, Frank ^a   Haenel, James ^b   Fullerton, David ^a   Banerjee, Anirban ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b DENVER HEALTH MEDICAL CENTER   (United States)

^c Bonfils Blood Center   (United States)

Author keywords

acute lung injury; acute respiratory distress syndrome; hemorrhagic shock; hypertonic saline; nebulizers; trauma; treatments

Indexed keywords

COLLAGENASE 3; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 1; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEMORRHAGIC SHOCK; INFLAMMATION; LUNG LAVAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RESUSCITATION;

ACUTE LUNG INJURY; ADMINISTRATION, INHALATION; ANIMALS; BIOPSY, NEEDLE; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; MALE; MATRIX METALLOPROTEINASE 13; NEBULIZERS AND VAPORIZERS; NEUTROPHIL INFILTRATION; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY DISTRESS SYNDROME, ADULT; SALINE SOLUTION, HYPERTONIC; SENSITIVITY AND SPECIFICITY; SHOCK, HEMORRHAGIC; WOUNDS AND INJURIES;

EID: 84865495096     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3182592006     Document Type: Article

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