A Salmonella typhimurium-translocated glycerophospholipid: Cholesterol acyltransferase promotes virulence by binding to the RhoA protein switch regions

Journal of Biological Chemistry

Volumn 287, Issue 35, 2012, Pages 29654-29663

  LaRock, Doris L ^a   Brzovic, Peter S ^b   Levin, Itay ^a   Blanc, Marie Pierre ^a   Miller, Samuel I ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL EFFECTOR; BACTERIAL PATHOGENS; BINDING SURFACE; CYTOSOLS; ENZYMATIC ACTIVITIES; EVOLUTIONARY STRATEGIES; GLYCEROPHOSPHOLIPIDS; GTPASES; HOST CELLS; HOST-PATHOGEN INTERACTIONS; MAMMALIAN CELLS; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; STRUCTURE-FUNCTION ANALYSIS;

CHOLESTEROL; EVOLUTIONARY ALGORITHMS; MAMMALS; SALMONELLA;

ACTIVATION ANALYSIS;

BACTERIAL ENZYME; CHOLESTEROL ACYLTRANSFERASE; GLYCEROPHOSPHOLIPID; MUTANT PROTEIN; PROTEIN SSEJ; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL VIRULENCE; BINDING COMPETITION; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME REGULATION; FEMALE; HOST PATHOGEN INTERACTION; INFECTION SENSITIVITY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHOLIPID TRANSFER; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY;

ACYLTRANSFERASES; ANIMALS; BACTERIAL PROTEINS; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; RHO GTP-BINDING PROTEINS; RHOA GTP-BINDING PROTEIN; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; STRUCTURE-ACTIVITY RELATIONSHIP; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); EUKARYOTA; MAMMALIA; MUS; SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SALMONELLA TYPHIMURIUM;

EID: 84865489460     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.363598     Document Type: Article

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