The preparation of N-substituted aminomethylidenebisphosphonates and their tetraalkyl esters via reaction of isonitriles with trialkyl phosphites and hydrogen chloride. Part 1

Tetrahedron Letters

Volumn 53, Issue 39, 2012, Pages 5290-5292

  Goldeman, Waldemar ^a   Kluczyński, Artur ^a   Soroka, Mirosław ^a  

^a WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Addition reactions; Aminobisphosphonate; Aminomethylidenebisphosphonate; Aminomethylidenebisphosphonic acid; Bisphosphonate; Bisphosphonic acid; Isonitrile; Proton assisted nucleophilic addition

Indexed keywords

AMINOMETHYLIDENEBISPHOSPHONIC ACID DERIVATIVE; ESTER DERIVATIVE; HYDROCHLORIC ACID; ISONITRILE DERIVATIVE; PHOSPHITE; PHOSPHONIC ACID DERIVATIVE; TETRAALKYL AMINOMETHYLIDENEBISPHOSPHONATE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DEALKYLATION; HYDROLYSIS;

EID: 84865477716     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2012.07.085     Document Type: Article

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