Ultra-sensitive molecular MRI of cerebrovascular cell activation enables early detection of chronic central nervous system disorders

NeuroImage

Volumn 63, Issue 2, 2012, Pages 760-770

  Montagne, Axel ^a   Gauberti, Maxime ^a   Macrez, Richard ^a,b   Jullienne, Amandine ^a   Briens, Aurélien ^a   Raynaud, Jean Sébastien ^c   Louin, Gaelle ^c   Buisson, Alain ^d   Haelewyn, Benoit ^e   Docagne, Fabian ^a   Defer, Gilles ^a,b   Vivien, Denis ^a   Maubert, Eric ^a  

^a UNIVERSITÉ DE CAEN   (France)

^b CAEN UNIVERSITY HOSPITAL   (France)

^c Laboratoire Guerbet   (France)

^d GRENOBLE INSTITUT DES NEUROSCIENCES   (France)

^e Centre Universitaire de Ressources Biologiques CURB   (France)

Author keywords

Alzheimer's disease; Molecular imaging; MRI; Multiple sclerosis; SPIO; Vascular dementia

Indexed keywords

ALCOHOL; CONTRAST MEDIUM; MICROPARTICLE OF IRON OXIDE; ULTRASMALL PARTICLE OF IRON OXIDE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

AGING; ALCOHOL CONSUMPTION; ALLERGIC ENCEPHALOMYELITIS; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DISEASE ASSOCIATION; ENDOTHELIUM CELL; HYPERGLYCEMIA; IMAGE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR IMAGING; MOUSE; MULTIINFARCT DEMENTIA; MULTIPLE SCLEROSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PERIPHERAL INFLAMMATION; PRIORITY JOURNAL; PROTEIN TARGETING; RISK FACTOR; SENSITIVITY ANALYSIS;

ANIMALS; BLOTTING, WESTERN; CENTRAL NERVOUS SYSTEM DISEASES; ENDOTHELIAL CELLS; FERRIC COMPOUNDS; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MALE; METAL NANOPARTICLES; MICE; MICE, INBRED C57BL; MOLECULAR IMAGING; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84865473927     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2012.07.018     Document Type: Article

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