-
1
-
-
84858434210
-
CNVs: Harbingers of a rare variant revolution in psychiatric genetics
-
Malhotra D, Sebat J. CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell 148(6), 1223-1241 (2012).
-
(2012)
Cell
, vol.148
, Issue.6
, pp. 1223-1241
-
-
Malhotra, D.1
Sebat, J.2
-
2
-
-
79957625912
-
Intermediate phenotypes in psychiatric disorders
-
Rasetti R, Weinberger DR. Intermediate phenotypes in psychiatric disorders. Curr. Opin. Genet. Dev. 21(3), 340-348 (2011).
-
(2011)
Curr. Opin. Genet. Dev.
, vol.21
, Issue.3
, pp. 340-348
-
-
Rasetti, R.1
Weinberger, D.R.2
-
3
-
-
80053384370
-
Genome-wide association study identifies five new schizophrenia loci
-
Ripke S, Sanders AR, Kendler KS et al. Genome-wide association study identifies five new schizophrenia loci. Nat. Genet. 43(10), 969-976 (2011).
-
(2011)
Nat. Genet.
, vol.43
, Issue.10
, pp. 969-976
-
-
Ripke, S.1
Sanders, A.R.2
Kendler, K.S.3
-
4
-
-
84856706805
-
Puzzling over schizophrenia: Schizophrenia as a pathway disease
-
Sullivan PF. Puzzling over schizophrenia: schizophrenia as a pathway disease. Nat. Med. 18(2), 210-211 (2012).
-
(2012)
Nat. Med.
, vol.18
, Issue.2
, pp. 210-211
-
-
Sullivan, P.F.1
-
5
-
-
79953826514
-
Disease-relevant autoantibodies in first episode schizophrenia
-
Zandi MS, Irani SR, Lang B et al. Disease-relevant autoantibodies in first episode schizophrenia. J. Neurol. 258(4), 686-688 (2011).
-
(2011)
J. Neurol.
, vol.258
, Issue.4
, pp. 686-688
-
-
Zandi, M.S.1
Irani, S.R.2
Lang, B.3
-
6
-
-
77956903409
-
Common variants in major histocompatibility complex region and TCF4 gene are significantly associated with schizophrenia in Han Chinese
-
Li T, Li Z, Chen P et al. Common variants in major histocompatibility complex region and TCF4 gene are significantly associated with schizophrenia in Han Chinese. Biol. Psychiatry 68(7), 671-673 (2010).
-
(2010)
Biol. Psychiatry
, vol.68
, Issue.7
, pp. 671-673
-
-
Li, T.1
Li, Z.2
Chen, P.3
-
7
-
-
45849127657
-
Intra-individual change over time in DNA methylation with familial clustering
-
□□ Demonstrates that the dynamics of global and gene-specific DNA methylation hyper-or hypo-methylation in peripheral blood cells has familial and thus genomic associations
-
Bjornsson HT, Sigurdsson MI, Fallin MD et al. Intra-individual change over time in DNA methylation with familial clustering. JAMA 299(24), 2877-2883 (2008). □□ Demonstrates that the dynamics of global and gene-specific DNA methylation (hyper-or hypo-methylation) in peripheral blood cells has familial (and thus genomic) associations.
-
(2008)
JAMA
, vol.299
, Issue.24
, pp. 2877-2883
-
-
Bjornsson, H.T.1
Sigurdsson, M.I.2
Fallin, M.D.3
-
9
-
-
34548715144
-
Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development
-
□□ The endocrine active compound bisphenol A found, for example, in the lining of food cans has global hypomethylation activities. In this article, the authors show, in a mouse model, that this effect can be counteracted by the one-carbon donor folate and the phytoestrogen genistein
-
Dolinoy DC, Huang D, Jirtle RL. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc. Natl Acad. Sci. USA 104(32), 13056-13061 (2007). □□ The endocrine active compound bisphenol A (found, for example, in the lining of food cans) has global hypomethylation activities. In this article, the authors show, in a mouse model, that this effect can be counteracted by the one-carbon donor folate and the phytoestrogen genistein.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.32
, pp. 13056-13061
-
-
Dolinoy, D.C.1
Huang, D.2
Jirtle, R.L.3
-
10
-
-
45549083182
-
Prenatal nutritional deficiency and risk of adult schizophrenia
-
Brown AS, Susser ES. Prenatal nutritional deficiency and risk of adult schizophrenia. Schizophr. Bull. 34(6), 1054-1063 (2008).
-
(2008)
Schizophr. Bull.
, vol.34
, Issue.6
, pp. 1054-1063
-
-
Brown, A.S.1
Susser, E.S.2
-
11
-
-
80052572090
-
Hungry in the womb: What are the consequences? Lessons from the Dutch famine
-
Roseboom TJ, Painter RC, Van Abeelen AF, Veenendaal MV, De Rooij SR. Hungry in the womb: what are the consequences? Lessons from the Dutch famine. Maturitas 70(2), 141-145 (2011).
-
(2011)
Maturitas
, vol.70
, Issue.2
, pp. 141-145
-
-
Roseboom, T.J.1
Painter, R.C.2
Van Abeelen, A.F.3
Veenendaal, M.V.4
De Rooij, S.R.5
-
12
-
-
3342989681
-
Epigenetic programming by maternal behavior
-
Weaver IC, Cervoni N, Champagne FA et al. Epigenetic programming by maternal behavior. Nat. Neurosci. 7(8), 847-854 (2004).
-
(2004)
Nat. Neurosci.
, vol.7
, Issue.8
, pp. 847-854
-
-
Weaver, I.C.1
Cervoni, N.2
Champagne, F.A.3
-
13
-
-
60749105468
-
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
-
□□ The sequel to a rat model study 12 of the epigenetic effects by early maternal behavior on the rat pup glucocorticoid receptor promoter and later adult stress response. This study extends this to humans, and describes a similar DNA methylation effect by abuse in early childhood life
-
McGowan PO, Sasaki A, D'alessio AC et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat. Neurosci. 12(3), 342-348 (2009). □□ The sequel to a rat model study [12] of the epigenetic effects by early maternal behavior on the rat pup glucocorticoid receptor promoter and later adult stress response. This study extends this to humans, and describes a similar DNA methylation effect by abuse in early childhood life.
-
(2009)
Nat. Neurosci.
, vol.12
, Issue.3
, pp. 342-348
-
-
McGowan, P.O.1
Sasaki, A.2
D'alessio, A.C.3
-
14
-
-
66749192609
-
Epigenetic modulation at birth - Altered DNAmethylation in white blood cells after Caesarean section
-
Schlinzig T, Johansson S, Gunnar A, Ekström TJ, Norman M. Epigenetic modulation at birth - altered DNAmethylation in white blood cells after Caesarean section. Acta Paediatr. 98(7), 1096-1099 (2009).
-
(2009)
Acta Paediatr.
, vol.98
, Issue.7
, pp. 1096-1099
-
-
Schlinzig, T.1
Johansson, S.2
Gunnar, A.3
Ekström, T.J.4
Norman, M.5
-
15
-
-
84859499394
-
Epigenetic and post-transcriptional dysregulation of gene expression in schizophrenia and related disease
-
Gavin DP, Akbarian S. Epigenetic and post-transcriptional dysregulation of gene expression in schizophrenia and related disease. Neurobiol. Dis. 46(2), 255-262 (2012).
-
(2012)
Neurobiol. Dis.
, vol.46
, Issue.2
, pp. 255-262
-
-
Gavin, D.P.1
Akbarian, S.2
-
16
-
-
79954612114
-
Epigenetic GABAergic targets in schizophrenia and bipolar disorder
-
□□ Review of epigenetic regulation of GABAergic signaling in schizophrenia and bipolar disorder
-
Guidotti A, Auta J, Chen Y et al. Epigenetic GABAergic targets in schizophrenia and bipolar disorder. Neuropharmacology 60(7-8), 1007-1016 (2011). □□ Review of epigenetic regulation of GABAergic signaling in schizophrenia and bipolar disorder.
-
(2011)
Neuropharmacology
, vol.60
, Issue.7-8
, pp. 1007-1016
-
-
Guidotti, A.1
Auta, J.2
Chen, Y.3
-
17
-
-
68349086839
-
Epigenetic mechanisms in schizophrenia
-
Roth TL, Lubin FD, Sodhi M, Kleinman JE. Epigenetic mechanisms in schizophrenia. Biochim. Biophys. Acta 1790(9), 869-877 (2009).
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, Issue.9
, pp. 869-877
-
-
Roth, T.L.1
Lubin, F.D.2
Sodhi, M.3
Kleinman, J.E.4
-
18
-
-
81855183787
-
Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder
-
Dempster EL, Pidsley R, Schalkwyk LC et al. Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum. Mol. Genet. 20(24), 4786-4796 (2011).
-
(2011)
Hum. Mol. Genet.
, vol.20
, Issue.24
, pp. 4786-4796
-
-
Dempster, E.L.1
Pidsley, R.2
Schalkwyk, L.C.3
-
19
-
-
0035007327
-
GABAergic interneurons: Implications for understanding schizophrenia and bipolar disorder
-
Benes FM, Berretta S. GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology 25(1), 1-27 (2001).
-
(2001)
Neuropsychopharmacology
, vol.25
, Issue.1
, pp. 1-27
-
-
Benes, F.M.1
Berretta, S.2
-
20
-
-
41149140859
-
Epigenomic profiling reveals DNA-methylation changes associated with major psychosis
-
Mill J, Tang T, Kaminsky Z et al. Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. Am. J. Hum. Genet. 82(3), 696-711 (2008).
-
(2008)
Am. J. Hum. Genet.
, vol.82
, Issue.3
, pp. 696-711
-
-
Mill, J.1
Tang, T.2
Kaminsky, Z.3
-
21
-
-
84861775810
-
Epigenetic aberrations in leukocytes of patients with schizophrenia: Association of global DNA methylation with antipsychotic drug treatment and disease onset
-
□□ Demonstrates that global methylation in leukocytes was lower in schizophrenia patients, with a more marked hypomethylation in those with early onset and a methylation effect by antipsychotic treatment
-
Melas PA, Rogdaki M, Osby U, Schalling M, Lavebratt C, Ekström TJ. Epigenetic aberrations in leukocytes of patients with schizophrenia: association of global DNA methylation with antipsychotic drug treatment and disease onset. FASEB J. 26(6), 2712-2718 (2012). □□ Demonstrates that global methylation in leukocytes was lower in schizophrenia patients, with a more marked hypomethylation in those with early onset and a methylation effect by antipsychotic treatment.
-
(2012)
FASEB J.
, vol.26
, Issue.6
, pp. 2712-2718
-
-
Melas, P.A.1
Rogdaki, M.2
Osby, U.3
Schalling, M.4
Lavebratt, C.5
Ekström, T.J.6
-
22
-
-
34547629199
-
Pathophysiology of early onset schizophrenia
-
Kyriakopoulos M, Frangou S. Pathophysiology of early onset schizophrenia. Int. Rev. Psychiatry 19(4), 315-324 (2007).
-
(2007)
Int. Rev. Psychiatry
, vol.19
, Issue.4
, pp. 315-324
-
-
Kyriakopoulos, M.1
Frangou, S.2
-
23
-
-
70449864112
-
Activation of brain interleukin-1b in schizophrenia
-
Söderlund J, Schroder J, Nordin C et al. Activation of brain interleukin-1b in schizophrenia. Mol. Psychiatry 14(12), 1069-1071 (2009).
-
(2009)
Mol. Psychiatry
, vol.14
, Issue.12
, pp. 1069-1071
-
-
Söderlund, J.1
Schroder, J.2
Nordin, C.3
-
24
-
-
80052617964
-
Is DNA methylation responsible for immune system dysfunction in schizophrenia?
-
Khojasteh-Fard M, Tabrizi M, Amoli MM. Is DNA methylation responsible for immune system dysfunction in schizophrenia? Med. Hypotheses 77(4), 573-579 (2011).
-
(2011)
Med. Hypotheses
, vol.77
, Issue.4
, pp. 573-579
-
-
Khojasteh-Fard, M.1
Tabrizi, M.2
Amoli, M.M.3
-
25
-
-
80051971949
-
New concepts of old epigenetic phenomena and their implications for selecting specific cell populations for epigenomic research
-
Herceg Z, Hernandez-Vargas H. New concepts of old epigenetic phenomena and their implications for selecting specific cell populations for epigenomic research. Epigenomics 3(4), 383-386 (2011).
-
(2011)
Epigenomics
, vol.3
, Issue.4
, pp. 383-386
-
-
Herceg, Z.1
Hernandez-Vargas, H.2
|