Boström et al. reply

Nature

Volumn 488, Issue 7413, 2012, Pages

  Boström, Pontus ^a   Wu, Jun ^a   Jedrychowski, Mark P ^a   Korde, Anisha ^a   Ye, Li ^a   Lo, James C ^a   Rasbach, Kyle A ^a   Boström, Elisabeth Almer ^b   Choi, Jang Hyun ^a   Long, Jonathan Z ^a   Kajimura, Shingo ^c   Zingaretti, Maria Cristina ^d   Vind, Birgitte F ^e   Tu, Hua ^f   Cinti, Saverio ^d   Hojlund, Kurt ^e   Gygi, Steven P ^a   Spiegelman, Bruce M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^e ODENSE UNIVERSITY HOSPITAL   (Denmark)

^f LakePharma Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

AEROBIC EXERCISE; GENE; GENE ACTIVATION; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; INSULIN SENSITIVITY; IRISIN GENE; NOTE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

EID: 84865471902     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11365     Document Type: Note

References (6)

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2. Boström, P. et al. A PGC1-a-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 831, 463-468 (2012).
3. Perry, C. G. R. et al. Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle. J. Physiol. 588, 4795-4810 (2010).
4. Ristow, M. et al. Antioxidants prevent health-promoting effects of physical exercise in humans. Proc. Natl Acad. Sci. USA 106, 8665-8670 (2009).
5. Vissing, K. et al. Effect of sex differences on human MEF2 regulation during endurance exercise. Am. J. Physiol. Endocrinol. Metab. 294, E405-E415 (2008).
6. Little, J. P., Safdar, A., Bishop, D., Tarnopolsky, M. A. & Gibala, M. J. An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1a and activates mitochondrial biogenesis in human skeletal muscle. Am. J. Physiol. Int. Comp. Physiol. 300, R1303-R1310 (2011).