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Volumn 7, Issue 9, 2012, Pages 757-759

Systems drug discovery: A quantitative, objective approach for safer drug development

Author keywords

high content screening; metabolomics; natural compounds; synthetic biology; systems biology; systems drug discovery; transcriptomics

Indexed keywords

DIGITALIS; MORPHINE; OPIATE; PENICILLIN G; PURINE DERIVATIVE; SALICYLIC ACID;

EID: 84865468939     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2012.710197     Document Type: Review
Times cited : (5)

References (10)
  • 1
    • 84856509534 scopus 로고    scopus 로고
    • 2011 FDA drug approvals
    • Mullard A. 2011 FDA drug approvals. Nat Rev Drug Discov 2012;11(2):91-4
    • (2012) Nat Rev Drug Discov , vol.11 , Issue.2 , pp. 91-94
    • Mullard, A.1
  • 2
    • 33947594385 scopus 로고    scopus 로고
    • Clinical forecasting in drug development
    • Schachter AD, Ramoni MF. Clinical forecasting in drug development. Nat Rev Drug Discov 2007;6(2):107-8
    • (2007) Nat Rev Drug Discov , vol.6 , Issue.2 , pp. 107-108
    • Schachter, A.D.1    Ramoni, M.F.2
  • 3
    • 84857743319 scopus 로고    scopus 로고
    • Diagnosing the decline in pharmaceutical R&D efficiency
    • Scannell JW, Blanckley A, Boldon H, et al. Diagnosing the decline in pharmaceutical R&D efficiency. Nat Rev Drug Discov 2012;11(3):191-200
    • (2012) Nat Rev Drug Discov , vol.11 , Issue.3 , pp. 191-200
    • Scannell, J.W.1    Blanckley, A.2    Boldon, H.3
  • 4
    • 0003183507 scopus 로고
    • The chemistry and biochemistry of purine analogs
    • Hitchings GH, Elion GB. The chemistry and biochemistry of purine analogs. Ann NY Acad Sci 1954; 60(2):195-9
    • (1954) Ann NY Acad Sci , vol.60 , Issue.2 , pp. 195-199
    • Hitchings, G.H.1    Elion, G.B.2
  • 5
    • 34548295338 scopus 로고    scopus 로고
    • Origin and evolution of high throughput screening
    • Pereira DA, Williams JA. Origin and evolution of high throughput screening. Br J Pharmacol 2007;152(1):53-61
    • (2007) Br J Pharmacol , vol.152 , Issue.1 , pp. 53-61
    • Pereira, D.A.1    Williams, J.A.2
  • 6
    • 79959929769 scopus 로고    scopus 로고
    • How were new medicines discovered?
    • Swinney DC, Anthony J. How were new medicines discovered? Nat Rev Drug Discov 2011;10(7):507-19
    • (2011) Nat Rev Drug Discov , vol.10 , Issue.7 , pp. 507-519
    • Swinney, D.C.1    Anthony, J.2
  • 7
    • 84858308226 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the 30 years from 1981 to 2010
    • Newman DJ, Cragg GM. Natural products as sources of new drugs over the 30 years from 1981 to 2010. J Nat Prod 2012;75(3):311-35
    • (2012) J Nat Prod , vol.75 , Issue.3 , pp. 311-335
    • Newman, D.J.1    Cragg, G.M.2
  • 8
    • 52049109838 scopus 로고    scopus 로고
    • Natural products in drug discovery
    • Harvey AL. Natural products in drug discovery. Drug Discov Today 2008;13(19/20):894-901
    • (2008) Drug Discov Today , vol.13 , Issue.19-20 , pp. 894-901
    • Harvey, A.L.1
  • 9
    • 34347405756 scopus 로고    scopus 로고
    • A quantitative method for analysis of in vitro neurite outgrowth
    • Mitchell PJ, Hanson JC, Quets-Nguyen AT, et al. A quantitative method for analysis of in vitro neurite outgrowth. J Neurosci Methods 2007;164(2):350
    • (2007) J Neurosci Methods , vol.164 , Issue.2 , pp. 350
    • Mitchell, P.J.1    Hanson, J.C.2    Quets-Nguyen, A.T.3
  • 10
    • 79961008636 scopus 로고    scopus 로고
    • Natural products from synthetic biology
    • Wayne M. Natural products from synthetic biology. Curr Opin Chem Biol 2011;15(4):505-15
    • (2011) Curr Opin Chem Biol , vol.15 , Issue.4 , pp. 505-515
    • Wayne, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.