-
1
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, et al Cancer statistics, 2010. CA Cancer J Clin. 2010; 60: 277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
-
2
-
-
63849092341
-
Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: clinical outcomes and plasma angiogenesis markers
-
doi: 10.1186/1471-2407-9-82.
-
Kontovinis LF, Papazisis KT, Touplikioti P, et al Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: clinical outcomes and plasma angiogenesis markers. BMC Cancer. 2009; 9: 82. doi: 10.1186/1471-2407-9-82.
-
(2009)
BMC Cancer
, vol.9
, pp. 82
-
-
Kontovinis, L.F.1
Papazisis, K.T.2
Touplikioti, P.3
-
3
-
-
79956317112
-
von Hippel-Lindau disease: a clinical and scientific review
-
Maher ER, Neumann HP, Richard S. von Hippel-Lindau disease: a clinical and scientific review. Eur J Hum Genet. 2011; 19: 617-23.
-
(2011)
Eur J Hum Genet
, vol.19
, pp. 617-623
-
-
Maher, E.R.1
Neumann, H.P.2
Richard, S.3
-
4
-
-
76449094050
-
Understanding the molecular-based mechanism of action of the tyrosine kinase inhibitor: sunitinib
-
Mena AC, Pulido EG, Guillén-Ponce C. Understanding the molecular-based mechanism of action of the tyrosine kinase inhibitor: sunitinib. Anticancer Drugs. 2010; 21: S3-11.
-
(2010)
Anticancer Drugs.
, vol.21
-
-
Mena, A.C.1
Pulido, E.G.2
Guillén-Ponce, C.3
-
5
-
-
34548310428
-
Sunitinib malate for the treatment of metastatic renal cell carcinoma and gastrointestinal stromal tumours
-
Adams VR, Leggas M. Sunitinib malate for the treatment of metastatic renal cell carcinoma and gastrointestinal stromal tumours. Clin Ther. 2007; 29: 1338-53.
-
(2007)
Clin Ther
, vol.29
, pp. 1338-1353
-
-
Adams, V.R.1
Leggas, M.2
-
6
-
-
34548316976
-
Molecular basis for sunitinib efficacy and future clinical development
-
Faivre S, Demetri G, Sargent W, et al Molecular basis for sunitinib efficacy and future clinical development. Nat Rev Drug Discov. 2007; 6: 734-45.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 734-745
-
-
Faivre, S.1
Demetri, G.2
Sargent, W.3
-
7
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship
-
Mendel DB, Laird AD, Xin X, et al In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res. 2003; 9: 327-37.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
-
8
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
O'Farrell AM, Abrams TJ, Yuen HA, et al SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood. 2003; 101: 3597-605.
-
(2003)
Blood
, vol.101
, pp. 3597-3605
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
-
9
-
-
77949429364
-
Sunitinib for the management of advanced renal cell carcinoma
-
Escudier B. Sunitinib for the management of advanced renal cell carcinoma. Expert Rev Anticancer Ther. 2010; 10: 305-17.
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, pp. 305-317
-
-
Escudier, B.1
-
10
-
-
33644833910
-
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
-
Motzer RJ, Michaelson MD, Redman BG, et al Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol. 2006; 24: 16-24.
-
(2006)
J Clin Oncol
, vol.24
, pp. 16-24
-
-
Motzer, R.J.1
Michaelson, M.D.2
Redman, B.G.3
-
11
-
-
33744954585
-
Sunitinib in patients with metastatic renal cell carcinoma
-
Motzer RJ, Rini BI, Bukowski RM, et al Sunitinib in patients with metastatic renal cell carcinoma. JAMA. 2006; 295: 2516-24.
-
(2006)
JAMA
, vol.295
, pp. 2516-2524
-
-
Motzer, R.J.1
Rini, B.I.2
Bukowski, R.M.3
-
12
-
-
33846181370
-
Sunitinib versus interferon alpha in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, et al Sunitinib versus interferon alpha in metastatic renal-cell carcinoma. N Engl J Med. 2007; 356: 115-24.
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
13
-
-
33845313345
-
The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review
-
Eskens FA, Verweij J. The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review. Eur J Cancer. 2006; 42: 3127-39.
-
(2006)
Eur J Cancer
, vol.42
, pp. 3127-3139
-
-
Eskens, F.A.1
Verweij, J.2
-
14
-
-
41149108218
-
Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma
-
Bhojani N, Jeldres C, Patard JJ, et al Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma. Eur Urol. 2008; 53: 917-30.
-
(2008)
Eur Urol
, vol.53
, pp. 917-930
-
-
Bhojani, N.1
Jeldres, C.2
Patard, J.J.3
-
15
-
-
79959269606
-
Treatment of metastatic renal cell carcinoma and renal pelvic cancer
-
Tanji N, Yokoyama M. Treatment of metastatic renal cell carcinoma and renal pelvic cancer. Clin Exp Nephrol. 2011; 15: 331-8.
-
(2011)
Clin Exp Nephrol
, vol.15
, pp. 331-338
-
-
Tanji, N.1
Yokoyama, M.2
-
17
-
-
79955845255
-
Targeted therapies for the treatment of metastatic renal cell carcinoma: clinical evidence
-
Hutson TE. Targeted therapies for the treatment of metastatic renal cell carcinoma: clinical evidence. Oncologist. 2011; 16: 14-22.
-
(2011)
Oncologist
, vol.16
, pp. 14-22
-
-
Hutson, T.E.1
-
18
-
-
79955037961
-
Update on targeted therapies for clear cell renal cell carcinoma
-
Singer EA, Gupta GN, Srinivasan R. Update on targeted therapies for clear cell renal cell carcinoma. Curr Opin Oncol. 2011; 23: 283-9.
-
(2011)
Curr Opin Oncol
, vol.23
, pp. 283-289
-
-
Singer, E.A.1
Gupta, G.N.2
Srinivasan, R.3
-
19
-
-
65949118243
-
Combination targeted therapy in advanced renal cell carcinoma
-
Sosman J, Puzanov I. Combination targeted therapy in advanced renal cell carcinoma. Cancer. 2009; 115: 2368-75.
-
(2009)
Cancer
, vol.115
, pp. 2368-2375
-
-
Sosman, J.1
Puzanov, I.2
-
20
-
-
50549086998
-
Economic evaluation of sunitinib malate for the first-line treatment of metastatic renal cell carcinoma
-
Remák E, Charbonneau C, Négrier S, et al Economic evaluation of sunitinib malate for the first-line treatment of metastatic renal cell carcinoma. J Clin Oncol. 2008; 26: 3995-4000.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3995-4000
-
-
Remák, E.1
Charbonneau, C.2
Négrier, S.3
-
21
-
-
77958573019
-
Expression of follicle-stimulating hormone receptor in tumour blood vessels
-
Radu A, Pichon C, Camparo P, et al Expression of follicle-stimulating hormone receptor in tumour blood vessels. N Engl J Med. 2010; 363: 1621-30.
-
(2010)
N Engl J Med
, vol.363
, pp. 1621-1630
-
-
Radu, A.1
Pichon, C.2
Camparo, P.3
-
22
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
-
Eisenhauer EA, Therasse P, Bogaerts J, et al New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1). Eur J Cancer. 2009; 45: 228-47.
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
-
23
-
-
0030059066
-
Anti-human FSH receptor monoclonal antibodies: immunochemical and immunocytochemical characterization of the receptor
-
Vannier B, Loosfelt H, Meduri G, et al Anti-human FSH receptor monoclonal antibodies: immunochemical and immunocytochemical characterization of the receptor. Biochemistry. 1996; 35: 1358-66.
-
(1996)
Biochemistry
, vol.35
, pp. 1358-1366
-
-
Vannier, B.1
Loosfelt, H.2
Meduri, G.3
-
24
-
-
77951093888
-
Predictive value of baseline serum vascular endothelial growth factor and neutrophil gelatinase-associated lipocalin in advanced kidney cancer patients receiving sunitinib
-
Porta C, Paglino C, De Amici M, et al Predictive value of baseline serum vascular endothelial growth factor and neutrophil gelatinase-associated lipocalin in advanced kidney cancer patients receiving sunitinib. Kidney Int. 2010; 77: 809-15.
-
(2010)
Kidney Int
, vol.77
, pp. 809-815
-
-
Porta, C.1
Paglino, C.2
De Amici, M.3
-
25
-
-
77956270281
-
Soluble isoforms of vascular endothelial growth factor are predictors of response to sunitinib in metastatic renal cell carcinomas
-
Paule B, Bastien L, Deslandes E, et al Soluble isoforms of vascular endothelial growth factor are predictors of response to sunitinib in metastatic renal cell carcinomas. PLoS One. 2010; 5: e10715.
-
(2010)
PLoS One.
, vol.5
-
-
Paule, B.1
Bastien, L.2
Deslandes, E.3
-
26
-
-
79952538238
-
Fibroblast growth factor 2 regulates endothelial cell sensitivity to sunitinib
-
Welti JC, Gourlaouen M, Powles T, et al Fibroblast growth factor 2 regulates endothelial cell sensitivity to sunitinib. Oncogene. 2011; 30: 1183-93.
-
(2011)
Oncogene
, vol.30
, pp. 1183-1193
-
-
Welti, J.C.1
Gourlaouen, M.2
Powles, T.3
-
27
-
-
79851482955
-
Sunitinib malate for the treatment of pancreatic neuroendocrine tumours
-
Raymond E, Dahan L, Raoul JL, et al Sunitinib malate for the treatment of pancreatic neuroendocrine tumours. N Engl J Med. 2011; 364: 501-13.
-
(2011)
N Engl J Med
, vol.364
, pp. 501-513
-
-
Raymond, E.1
Dahan, L.2
Raoul, J.L.3
-
28
-
-
76249126867
-
Sunitinib acts primarily on tumour endothelium rather than tumour cells to inhibit the growth of renal cell carcinoma
-
Huang D, Ding Y, Li Y, et al Sunitinib acts primarily on tumour endothelium rather than tumour cells to inhibit the growth of renal cell carcinoma. Cancer Res. 2010; 70: 1053-62.
-
(2010)
Cancer Res
, vol.70
, pp. 1053-1062
-
-
Huang, D.1
Ding, Y.2
Li, Y.3
-
29
-
-
59649102824
-
Role of the phosphatidylinositol-3-kinase and extracellular regulated kinase pathways in the induction of hypoxia-inducible factor (HIF)-1 activity and the HIF-1 target vascular endothelial growth factor in ovarian granulosa cells in response to follicle-stimulating hormone
-
Alam H, Weck J, Maizels E, et al Role of the phosphatidylinositol-3-kinase and extracellular regulated kinase pathways in the induction of hypoxia-inducible factor (HIF)-1 activity and the HIF-1 target vascular endothelial growth factor in ovarian granulosa cells in response to follicle-stimulating hormone. Endocrinology. 2009; 150: 915-28.
-
(2009)
Endocrinology
, vol.150
, pp. 915-928
-
-
Alam, H.1
Weck, J.2
Maizels, E.3
|