Declining Physical Capacity But Maintained Aerobic Activity in Early Alzheimer's Disease

American Journal of Alzheimer's Disease & Other Dementias®

Volumn 27, Issue 3, 2012, Pages 180-187

  Cedervall, Ylva ^a   Kilander, Lena ^a   Åberg, Anna Cristina ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

dementia; longitudinal; physical activity; timed up and go; walking

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; EXERCISE; FEMALE; FOLLOW UP; HUMAN; LONGITUDINAL STUDY; MALE; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PHYSICAL EXAMINATION;

AGED; ALZHEIMER DISEASE; EXERCISE; FEMALE; FOLLOW-UP STUDIES; HUMANS; LONGITUDINAL STUDIES; MALE; NEUROPSYCHOLOGICAL TESTS; PHYSICAL EXAMINATION;

EID: 84865437194     PISSN: 15333175     EISSN: 19382731     Source Type: Journal    
DOI: 10.1177/1533317512442996     Document Type: Article

References (53)

1. Eggermont LH Gavett BE Volkers KM, et al Lower-extremity function in cognitively healthy aging, mild cognitive impairment, and Alzheimer-s disease. Arch Phys Med Rehabil. 2010; 91(4):584-588.
2. Pettersson AF Olsson E Wahlund LO. Motor function in subjects with mild cognitive impairment and early Alzheimer-s disease. Dement Geriatr Cogn Disord. 2005; 19(5-6):299-304.
3. Wittwer JE Andrews PT Webster KE Menz HB. Timing variability during gait initiation is increased in people with Alzheimer-s disease compared to controls. Dement Geriatr Cogn Disord. 2008; 26(3):277-283.
4. Sheridan PL Hausdorff JM. The role of higher-level cognitive function in gait: executive dysfunction contributes to fall risk in Alzheimer-s disease. Dement Geriatr Cogn Disord. 2007; 24(2):125-137.
5. Sheridan PL Solomont J Kowall N Hausdorff JM. Influence of executive function on locomotor function: divided attention increases gait variability in Alzheimer-s disease. J Am Geriatr Soc. 2003; 51(11):1633-1637.
6. McGuinness B Barrett SL Craig D Lawson J Passmore AP. Attention deficits in Alzheimer-s disease and vascular dementia. J Neurol Neurosurg Psychiatry. 2010; 81(2):157-159.
7. McGuinness B Barrett SL Craig D Lawson J Passmore AP. Executive functioning in Alzheimer-s disease and vascular dementia. Int J Geriatr Psychiatry. 2010; 25(6):562-568.
8. Muir SW Speechley M Wells J Borrie M Gopaul K Montero-Odasso M. Gait assessment in mild cognitive impairment and Alzheimer-s disease: the effect of dual-task challenges across the cognitive spectrum. Gait Posture. 2012; 35(1):96-100.
9. Pettersson AF Engardt M Wahlund LO. Activity level and balance in subjects with mild Alzheimer-s disease. Dement Geriatr Cogn Disord. 2002; 13(4):213-216.
10. Burns JM Mayo MS Anderson HS Smith HJ Donnelly JE. Cardiorespiratory fitness in early-stage Alzheimer disease. Alzheimer Dis Assoc Disord. 2008; 22(1):39-46.
11. Cook C Fay S Rockwood K. Decreased initiation of usual activities in people with mild-to-moderate Alzheimer-s disease: a descriptive analysis from the VISTA clinical trial. Int Psychogeriatr. 2008; 20(5):952-963.
12. World Health Organization. International Classification of Functioning, Disability and Health: ICF. Geneva: World Health Organization; 2001: 299s.
13. Nelson ME Rejeski WJ Blair SN, et al Physical activity and public health in older adults: recommendation from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc. 2007; 39(8):1435-1445.
14. World Health Organization. Global Recommendations on Physical Activity for Health. Switzerland: World Health Organization; 2010: 58.
15. Professional Associations for Physical activity SYffa, YFA. Physical Activity in the Prevention and Treatment of Disease. 2nd ed. Sweden: Swedish Naational Institute of Public Health; 2010: 623.
16. Erickson KI Voss MW Prakash RS, et al Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A. 2011; 108(7):3017-3022.
17. Baker LD Frank LL Foster-Schubert K, et al Effects of aerobic exercise on mild cognitive impairment: a controlled trial. Arch Neurol. 2010; 67(1):71-79.
18. Lautenschlager NT Cox KL Flicker L, et al Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial. JAMA. 2008; 300(9):1027-1037.
19. Makizako H Shimada H Doi T, et al The association between decline in physical functioning and atrophy of medial temporal areas in community-dwelling older adults with amnestic and nonamnestic mild cognitive impairment. Arch Phys Med Rehabil. 2011; 92(12):1992-1999.
20. Blankevoort CG van Heuvelen MJ Boersma F Luning H de Jong J Scherder E.J., Review of effects of physical activity on strength, balance, mobility and ADL performance in elderly subjects with dementia. Dement Geriatr Cogn Disord. 2010; 30(5):392-402.
21. Heyn P Abreu BC Ottenbacher KJ. The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis. Arch Phys Med Rehabil. 2004; 85(10):1694-1704.
22. Yu F Kolanowski AM Strumpf NE Eslinger PJ. Improving cognition and function through exercise intervention in Alzheimer-s disease. J Nurs Scholarsh. 2006; 38(4):358-365.
23. McDonnell MN Smith AE Mackintosh SF. Aerobic exercise to improve cognitive function in adults with neurological disorders: a systematic review. Arch Phys Med Rehabil. 2011; 92(7):1044-1052.
24. Fang Y. Guiding research and practice: a conceptual model for aerobic exercise training in Alzheimer-s disease. Am J Alzheimers Dis Other Demen. 2011; 26(3):184-194.
25. American, Psychiatric and Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR. Washington, DC: American Psychiatric Press; 2000.
26. McKhann G Drachman D Folstein M Katzman R Price D Stadlan E.M., Clinical diagnosis of Alzheimer-s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer-s Disease. Neurology. 1984; 34(7):939-944.
27. Folstein MF Folstein SE McHugh PR. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12(3):189-198.
28. Reisberg B. Functional assessment staging (FAST). Psychopharmacol Bull. 1988; 24(4):653-659.
29. Watson M. Refining the ten-metre walking test fo use with neurologically impaired people. Physiotherapy. 2002; 88: 386-397.
30. Bean JF Kiely DK Leveille SG, et al The 6-minute walk test in mobility-limited elders: what is being measured? J Gerontol. 2002; 57(11):M751-M756.
31. Steffen TM Hacker TA Mollinger L. Age- and gender-related test performance in community-dwelling elderly people: SIX-Minute Walk Test, Berg Balance Scale, Timed Up & Go Test, and gait speeds. Phys Ther. 2002; 82(2):128-137.
32. Podsiadlo D Richardson S. The timed “Up & Go”: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991; 39(2):142-148.
33. Shumway-Cook A Brauer S Woollacott M. Predicting the probability for falls in community-dwelling older adults using the Timed Up & Go Test. Phys Ther. 2000; 80(9):896-903.
34. Ries JD Echternach JL Nof L Gagnon Blodgett M. Test-retest reliability and minimal detectable change scores for the timed “up & go” test, the six-minute walk test, and gait speed in people with Alzheimer disease. Phys Ther. 2009; 89(6):569-579.
35. Bryman A. Social Research Methods. 2nd ed. Oxford, England: Oxford University Press; 2004: 592.
36. Ainsworth BE Haskell WL Whitt MC, et al Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc. 2000; 32(9 suppl):S498-S504.
37. Solomon PR Pendlebury WW. Recognition of Alzheimer-s disease: the 7 Minute Screen. Fam Med. 1998; 30(4):265-271.
38. Freedman M Leach L. Clock Drawing: A Neuropsychological Analysis. New York, NY: Oxford University Press Inc; 1994: 192.
39. Lezak M. Neuropsychological Assessment. 3rd ed. New York, NY: Oxford University Press; 1995: 1026.
40. Horak FB Wrisley DM Frank J. The Balance Evaluation Systems Test (BESTest) to differentiate balance deficits. Phys Ther. 2009; 89(5):484-498.
41. Pettersson AF Olsson E Wahlund LO. Effect of divided attention on gait in subjects with and without cognitive impairment. J Geriatr Psychiatry Neurol. 2007; 20(1):58-62.
42. Snijders AH van de Warrenburg BP Giladi N Bloem BR. Neurological gait disorders in elderly people: clinical approach and classification. Lancet Neurol. 2007; 6(1):63-74.
43. Hausdorff JM Yogev G Springer S Simon ES Giladi N. Walking is more like catching than tapping: gait in the elderly as a complex cognitive task. Exp Brain Res. 2005; 164(4):541-548.
44. Wilson RS Leurgans SE Boyle PA Bennett DA. Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment. Arch Neurol. 2011; 68(3):351-356.
45. Verghese J Kuslansky G Holtzer R, et al Walking while talking: effect of task prioritization in the elderly. Arch Phys Med Rehabil. 2007; 88(1):50-53.
46. Cedervall Y Aberg AC. Physical activity and implications on well-being in mild Alzheimer-s disease: a qualitative case study on two men with dementia and their spouses. Physiother Theory Pract. 2010; 26(4):226-239.
47. Jansson W Nordberg G Grafstrom M. Patterns of elderly spousal caregiving in dementia care: an observational study. J Adv Nurs. 2001; 34(6):804-812.
48. McCurry SM Pike KC Logsdon RG Vitiello MV Larson EB Teri L. Predictors of short-and long-term adherence to a daily walking program in persons with Alzheimer-s disease. Am J Alzheimers Dis Other Demen. 2011; 25(6):505-512.
49. Scarmeas N Luchsinger JA Brickman AM, et al Physical activity and Alzheimer disease course. Am J Geriatr Psychiatry. 2010; 19(5):471-481.
50. Hillman CH Erickson KI Kramer AF. Be smart, exercise your heart: exercise effects on brain and cognition. Nat Rev Neurosci. 2008; 9(1):58-65.
51. Kramer AF Erickson KI. Capitalizing on cortical plasticity: influence of physical activity on cognition and brain function. Trends Cogn Sci. 2007; 11(8):342-348.
52. Forbes D Forbes S Morgan DG Markle-Reid M Wood J Culum I. Physical activity programs for persons with dementia. Cochrane Database Syst Rev. 2008;(3):CD006489.
53. Lautenschlager NT Cox K Kurz AF. Physical activity and mild cognitive impairment and Alzheimer-s disease. Curr Neurol Neurosci Rep. 2010; 10(5):352-358.