-
1
-
-
84455205655
-
The pathogenesis and diagnosis of acute kidney injury in multiple myeloma
-
Hutchison C.A., Batuman V., Behrens J., et al. The pathogenesis and diagnosis of acute kidney injury in multiple myeloma. Nat Rev Nephrol 2011, 8:43-51.
-
(2011)
Nat Rev Nephrol
, vol.8
, pp. 43-51
-
-
Hutchison, C.A.1
Batuman, V.2
Behrens, J.3
-
2
-
-
66349134261
-
Myeloma kidney: toward its prevention-with new insights from in vitro and in vivo models of renal injury
-
Sengul S., Li M., Batuman V. Myeloma kidney: toward its prevention-with new insights from in vitro and in vivo models of renal injury. J Nephrol 2009, 22:17-28.
-
(2009)
J Nephrol
, vol.22
, pp. 17-28
-
-
Sengul, S.1
Li, M.2
Batuman, V.3
-
3
-
-
49949114134
-
Silencing megalin and cubilin genes inhibits myeloma light chain endocytosis and ameliorates toxicity in human renal proximal tubule epithelial cells
-
Li M., Balamuthusamy S., Simon E.E., Batuman V. Silencing megalin and cubilin genes inhibits myeloma light chain endocytosis and ameliorates toxicity in human renal proximal tubule epithelial cells. Am J Physiol Renal Physiol 2008, 295:F82-F90.
-
(2008)
Am J Physiol Renal Physiol
, vol.295
-
-
Li, M.1
Balamuthusamy, S.2
Simon, E.E.3
Batuman, V.4
-
4
-
-
33751519297
-
Proximal tubular injury in myeloma
-
Batuman V. Proximal tubular injury in myeloma. Contrib Nephrol 2007, 153:87-104.
-
(2007)
Contrib Nephrol
, vol.153
, pp. 87-104
-
-
Batuman, V.1
-
5
-
-
11144318258
-
Light chains are a ligand for megalin
-
Klassen R.B., Allen P.L., Batuman V., Crenshaw K., Hammond T.G. Light chains are a ligand for megalin. J Appl Physiol 2005, 98:257-263.
-
(2005)
J Appl Physiol
, vol.98
, pp. 257-263
-
-
Klassen, R.B.1
Allen, P.L.2
Batuman, V.3
Crenshaw, K.4
Hammond, T.G.5
-
6
-
-
0036433583
-
Endocytosis of light chains induces cytokines through activation of NF-kappaB in human proximal tubule cells
-
Sengul S., Zwizinski C., Simon E.E., Kapasi A., Singhal P.C., Batuman V. Endocytosis of light chains induces cytokines through activation of NF-kappaB in human proximal tubule cells. Kidney Int 2002, 62:1977-1988.
-
(2002)
Kidney Int
, vol.62
, pp. 1977-1988
-
-
Sengul, S.1
Zwizinski, C.2
Simon, E.E.3
Kapasi, A.4
Singhal, P.C.5
Batuman, V.6
-
7
-
-
17344373956
-
Myeloma light chains are ligands for cubilin (gp280)
-
Batuman V., Verroust P.J., Navar G.L., et al. Myeloma light chains are ligands for cubilin (gp280). Am J Physiol 1998, 275(2 Pt 2):F246-F254.
-
(1998)
Am J Physiol
, vol.275
, Issue.2 PART 2
-
-
Batuman, V.1
Verroust, P.J.2
Navar, G.L.3
-
8
-
-
33751326779
-
Receptor-mediated endocytosis of immunoglobulin light chains by renal proximal tubule cells
-
Batuman V., Guan S. Receptor-mediated endocytosis of immunoglobulin light chains by renal proximal tubule cells. Am J Physiol 1997, 272(4 Pt 2):F521-F530.
-
(1997)
Am J Physiol
, vol.272
, Issue.4 PART 2
-
-
Batuman, V.1
Guan, S.2
-
9
-
-
85105423700
-
Urinary immunoglobulin components in normal, tubular, and glomerular proteinuria: quantities and characteristics of free light chains, IgG, IgA, and Fc-gamma fragment
-
Peterson P.A., Berggard I. Urinary immunoglobulin components in normal, tubular, and glomerular proteinuria: quantities and characteristics of free light chains, IgG, IgA, and Fc-gamma fragment. Eur J Clin Invest 1971, 1:255-264.
-
(1971)
Eur J Clin Invest
, vol.1
, pp. 255-264
-
-
Peterson, P.A.1
Berggard, I.2
-
10
-
-
17044458969
-
Adult Fanconi syndrome secondary to light chain gammopathy. Clinicopathologic heterogeneity and unusual features in 11 patients
-
Messiaen T., Deret S., Mougenot B., et al. Adult Fanconi syndrome secondary to light chain gammopathy. Clinicopathologic heterogeneity and unusual features in 11 patients. Medicine (Baltimore) 2000, 79:135-154.
-
(2000)
Medicine (Baltimore)
, vol.79
, pp. 135-154
-
-
Messiaen, T.1
Deret, S.2
Mougenot, B.3
-
11
-
-
84925946359
-
Role of proximal tubules in the pathogenesis of kidney disease
-
Nakhoul N., Batuman V. Role of proximal tubules in the pathogenesis of kidney disease. Contrib Nephrol 2011, 169:37-50.
-
(2011)
Contrib Nephrol
, vol.169
, pp. 37-50
-
-
Nakhoul, N.1
Batuman, V.2
-
12
-
-
77953949376
-
Myeloma light chain-induced renal injury in mice
-
Khan A.M., Li M., Balamuthusamy S., Maderdrut J.L., Simon E.E., Batuman V. Myeloma light chain-induced renal injury in mice. Nephron Exp Nephrol 2010, 116:e32-e41.
-
(2010)
Nephron Exp Nephrol
, vol.116
-
-
Khan, A.M.1
Li, M.2
Balamuthusamy, S.3
Maderdrut, J.L.4
Simon, E.E.5
Batuman, V.6
-
13
-
-
42449118069
-
Myeloma light chains induce epithelial-mesenchymal transition in human renal proximal tubule epithelial cells
-
Li M., Hering-Smith K.S., Simon E.E., Batuman V. Myeloma light chains induce epithelial-mesenchymal transition in human renal proximal tubule epithelial cells. Nephrol Dial Transplant 2008, 23:860-870.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 860-870
-
-
Li, M.1
Hering-Smith, K.S.2
Simon, E.E.3
Batuman, V.4
-
14
-
-
30444455781
-
Potential protective action of pituitary adenylate cyclase-activating polypeptide (PACAP38) on in vitro and in vivo models of myeloma kidney injury
-
Arimura A., Li M., Batuman V. Potential protective action of pituitary adenylate cyclase-activating polypeptide (PACAP38) on in vitro and in vivo models of myeloma kidney injury. Blood 2006, 107:661-668.
-
(2006)
Blood
, vol.107
, pp. 661-668
-
-
Arimura, A.1
Li, M.2
Batuman, V.3
-
15
-
-
0037609534
-
Role of MAPK pathways in light chain-induced cytokine production in human proximal tubule cells
-
Sengul S., Zwizinski C., Batuman V. Role of MAPK pathways in light chain-induced cytokine production in human proximal tubule cells. Am J Physiol Renal Physiol 2003, 284:F1245-F1254.
-
(2003)
Am J Physiol Renal Physiol
, vol.284
-
-
Sengul, S.1
Zwizinski, C.2
Batuman, V.3
-
16
-
-
0033820718
-
Cytotoxicity of myeloma light chains in cultured human kidney proximal tubule cells
-
Pote A., Zwizinski C., Simon E.E., Meleg-Smith S., Batuman V. Cytotoxicity of myeloma light chains in cultured human kidney proximal tubule cells. Am J Kidney Dis 2000, 36:735-744.
-
(2000)
Am J Kidney Dis
, vol.36
, pp. 735-744
-
-
Pote, A.1
Zwizinski, C.2
Simon, E.E.3
Meleg-Smith, S.4
Batuman, V.5
-
17
-
-
0033228045
-
Inhibition of Na-K-ATPase activity and gene expression by a myeloma light chain in proximal tubule cells
-
Guan S., El-Dahr S., Dipp S., Batuman V. Inhibition of Na-K-ATPase activity and gene expression by a myeloma light chain in proximal tubule cells. J Invest Med 1999, 47:496-501.
-
(1999)
J Invest Med
, vol.47
, pp. 496-501
-
-
Guan, S.1
El-Dahr, S.2
Dipp, S.3
Batuman, V.4
-
18
-
-
0028076024
-
Effect of myeloma light chains on phosphate and glucose transport in renal proximal tubule cells
-
Batuman V., Guan S., O'Donovan R., Puschett J.B. Effect of myeloma light chains on phosphate and glucose transport in renal proximal tubule cells. Renal Physiol Biochem 1994, 17:294-300.
-
(1994)
Renal Physiol Biochem
, vol.17
, pp. 294-300
-
-
Batuman, V.1
Guan, S.2
O'Donovan, R.3
Puschett, J.B.4
-
19
-
-
0025330182
-
Light-chain binding sites on renal brush-border membranes
-
Batuman V., Dreisbach A.W., Cyran J. Light-chain binding sites on renal brush-border membranes. Am J Physiol 1990, 258(5 Pt 2):F1259-F1265.
-
(1990)
Am J Physiol
, vol.258
, Issue.5 PART 2
-
-
Batuman, V.1
Dreisbach, A.W.2
Cyran, J.3
-
20
-
-
0022817885
-
Light chain effects on alanine and glucose uptake by renal brush border membranes
-
Batuman V., Sastrasinh M., Sastrasinh S. Light chain effects on alanine and glucose uptake by renal brush border membranes. Kidney Int 1986, 30:662-665.
-
(1986)
Kidney Int
, vol.30
, pp. 662-665
-
-
Batuman, V.1
Sastrasinh, M.2
Sastrasinh, S.3
-
21
-
-
77954613885
-
Immunoglobulin light chains activate tubular epithelial cells through redox signaling
-
Basnayake K., Ying W.Z., Wang P.X., Sanders P.W. Immunoglobulin light chains activate tubular epithelial cells through redox signaling. J Am Soc Nephrol 2010, 21:1165-1173.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1165-1173
-
-
Basnayake, K.1
Ying, W.Z.2
Wang, P.X.3
Sanders, P.W.4
-
22
-
-
0027142560
-
Bence Jones proteins bind to a common peptide segment of Tamm-Horsfall glycoprotein to promote heterotypic aggregation
-
Huang Z.Q., Kirk K.A., Connelly K.G., Sanders P.W. Bence Jones proteins bind to a common peptide segment of Tamm-Horsfall glycoprotein to promote heterotypic aggregation. J Clin Invest 1993, 92:2975-2983.
-
(1993)
J Clin Invest
, vol.92
, pp. 2975-2983
-
-
Huang, Z.Q.1
Kirk, K.A.2
Connelly, K.G.3
Sanders, P.W.4
-
23
-
-
0029564962
-
Biochemical interaction between Tamm-Horsfall glycoprotein and Ig light chains in the pathogenesis of cast nephropathy
-
Huang Z.Q., Sanders P.W. Biochemical interaction between Tamm-Horsfall glycoprotein and Ig light chains in the pathogenesis of cast nephropathy. Lab Invest 1995, 73:810-817.
-
(1995)
Lab Invest
, vol.73
, pp. 810-817
-
-
Huang, Z.Q.1
Sanders, P.W.2
-
24
-
-
0031029279
-
Localization of a single binding site for immunoglobulin light chains on human Tamm-Horsfall glycoprotein
-
Huang Z.Q., Sanders P.W. Localization of a single binding site for immunoglobulin light chains on human Tamm-Horsfall glycoprotein. J Clin Invest 1997, 99:732-736.
-
(1997)
J Clin Invest
, vol.99
, pp. 732-736
-
-
Huang, Z.Q.1
Sanders, P.W.2
-
25
-
-
79551482312
-
Light chain-mediated tubulopathies
-
Sanders P.W. Light chain-mediated tubulopathies. Contrib Nephrol 2011, 169:262-269.
-
(2011)
Contrib Nephrol
, vol.169
, pp. 262-269
-
-
Sanders, P.W.1
-
26
-
-
0026607225
-
Pathobiology of cast nephropathy from human Bence Jones proteins
-
Sanders P.W., Booker B.B. Pathobiology of cast nephropathy from human Bence Jones proteins. J Clin Invest 1992, 89:630-639.
-
(1992)
J Clin Invest
, vol.89
, pp. 630-639
-
-
Sanders, P.W.1
Booker, B.B.2
-
27
-
-
0025020662
-
Mechanisms of intranephronal proteinaceous cast formation by low molecular weight proteins
-
Sanders P.W., Booker B.B., Bishop J.B., Cheung H.C. Mechanisms of intranephronal proteinaceous cast formation by low molecular weight proteins. J Clin Invest 1990, 85:570-576.
-
(1990)
J Clin Invest
, vol.85
, pp. 570-576
-
-
Sanders, P.W.1
Booker, B.B.2
Bishop, J.B.3
Cheung, H.C.4
-
28
-
-
0024209926
-
Differential nephrotoxicity of low molecular weight proteins including Bence Jones proteins in the perfused rat nephron in vivo
-
Sanders P.W., Herrera G.A., Chen A., Booker B.B., Galla J.H. Differential nephrotoxicity of low molecular weight proteins including Bence Jones proteins in the perfused rat nephron in vivo. J Clin Invest 1988, 82:2086-2096.
-
(1988)
J Clin Invest
, vol.82
, pp. 2086-2096
-
-
Sanders, P.W.1
Herrera, G.A.2
Chen, A.3
Booker, B.B.4
Galla, J.H.5
-
29
-
-
0023579996
-
Human Bence Jones protein toxicity in rat proximal tubule epithelium in vivo
-
Sanders P.W., Herrera G.A., Galla J.H. Human Bence Jones protein toxicity in rat proximal tubule epithelium in vivo. Kidney Int 1987, 32:851-861.
-
(1987)
Kidney Int
, vol.32
, pp. 851-861
-
-
Sanders, P.W.1
Herrera, G.A.2
Galla, J.H.3
-
30
-
-
0026408092
-
Spectrum of glomerular and tubulointerstitial renal lesions associated with monotypical immunoglobulin light chain deposition
-
Sanders P.W., Herrera G.A., Kirk K.A., Old C.W., Galla J.H. Spectrum of glomerular and tubulointerstitial renal lesions associated with monotypical immunoglobulin light chain deposition. Lab Invest 1991, 64:527-537.
-
(1991)
Lab Invest
, vol.64
, pp. 527-537
-
-
Sanders, P.W.1
Herrera, G.A.2
Kirk, K.A.3
Old, C.W.4
Galla, J.H.5
-
31
-
-
0023949795
-
Morphologic alterations of the proximal tubules in light chain-related renal disease
-
Sanders P.W., Herrera G.A., Lott R.L., Galla J.H. Morphologic alterations of the proximal tubules in light chain-related renal disease. Kidney Int 1988, 33:881-889.
-
(1988)
Kidney Int
, vol.33
, pp. 881-889
-
-
Sanders, P.W.1
Herrera, G.A.2
Lott, R.L.3
Galla, J.H.4
-
32
-
-
0035016941
-
Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall protein
-
Ying W.Z., Sanders P.W. Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall protein. Am J Pathol 2001, 158:1859-1866.
-
(2001)
Am J Pathol
, vol.158
, pp. 1859-1866
-
-
Ying, W.Z.1
Sanders, P.W.2
-
33
-
-
79251542049
-
Immunoglobulin light chains activate nuclear factor-kappaB in renal epithelial cells through a Src-dependent mechanism
-
Ying W.Z., Wang P.X., Aaron K.J., Basnayake K., Sanders P.W. Immunoglobulin light chains activate nuclear factor-kappaB in renal epithelial cells through a Src-dependent mechanism. Blood 2011, 117:1301-1307.
-
(2011)
Blood
, vol.117
, pp. 1301-1307
-
-
Ying, W.Z.1
Wang, P.X.2
Aaron, K.J.3
Basnayake, K.4
Sanders, P.W.5
-
34
-
-
0027207650
-
Monoclonal Ig L chain and L chain V domain fragment crystallization in myeloma-associated Fanconi's syndrome
-
Aucouturier P., Bauwens M., Khamlichi A.A., et al. Monoclonal Ig L chain and L chain V domain fragment crystallization in myeloma-associated Fanconi's syndrome. J Immunol 1993, 150(8 Pt 1):3561-3568.
-
(1993)
J Immunol
, vol.150
, Issue.8 PART 1
, pp. 3561-3568
-
-
Aucouturier, P.1
Bauwens, M.2
Khamlichi, A.A.3
-
35
-
-
0033570980
-
Mutational analysis in murine models for myeloma-associated Fanconi's syndrome or cast myeloma nephropathy
-
Decourt C., Rocca A., Bridoux F., et al. Mutational analysis in murine models for myeloma-associated Fanconi's syndrome or cast myeloma nephropathy. Blood 1999, 94:3559-3566.
-
(1999)
Blood
, vol.94
, pp. 3559-3566
-
-
Decourt, C.1
Rocca, A.2
Bridoux, F.3
-
36
-
-
79551471490
-
Toward understanding renal Fanconi syndrome: step by step advances through experimental models
-
Sirac C., Bridoux F., Essig M., Devuyst O., Touchard G., Cogne M. Toward understanding renal Fanconi syndrome: step by step advances through experimental models. Contrib Nephrol 2011, 169:247-261.
-
(2011)
Contrib Nephrol
, vol.169
, pp. 247-261
-
-
Sirac, C.1
Bridoux, F.2
Essig, M.3
Devuyst, O.4
Touchard, G.5
Cogne, M.6
-
37
-
-
0024222705
-
Differential toxicity of human Bence-Jones proteins in the rat proximal convoluted tubule in vivo
-
Galla J.H., Herrera G.A., Sanders P.W. Differential toxicity of human Bence-Jones proteins in the rat proximal convoluted tubule in vivo. Contrib Nephrol 1988, 68:198-202.
-
(1988)
Contrib Nephrol
, vol.68
, pp. 198-202
-
-
Galla, J.H.1
Herrera, G.A.2
Sanders, P.W.3
-
38
-
-
70349204642
-
Light chain proximal tubulopathy
-
Herlitz L.C., Roglieri J., Resta R., Bhagat G., Markowitz G.S. Light chain proximal tubulopathy. Kidney Int 2009, 76:792-797.
-
(2009)
Kidney Int
, vol.76
, pp. 792-797
-
-
Herlitz, L.C.1
Roglieri, J.2
Resta, R.3
Bhagat, G.4
Markowitz, G.S.5
-
39
-
-
33745952571
-
Role of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome
-
Sirac C., Bridoux F., Carrion C., et al. Role of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome. Blood 2006, 108:536-543.
-
(2006)
Blood
, vol.108
, pp. 536-543
-
-
Sirac, C.1
Bridoux, F.2
Carrion, C.3
-
40
-
-
34047234917
-
Immunoglobulin light chains generate hydrogen peroxide
-
Wang P.X., Sanders P.W. Immunoglobulin light chains generate hydrogen peroxide. J Am Soc Nephrol 2007, 18:1239-1245.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1239-1245
-
-
Wang, P.X.1
Sanders, P.W.2
-
41
-
-
0027352826
-
Potential role of colchicine in the prevention of cast nephropathy from Bence Jones proteins
-
Sanders P.W. Potential role of colchicine in the prevention of cast nephropathy from Bence Jones proteins. Contrib Nephrol 1993, 101:104-108.
-
(1993)
Contrib Nephrol
, vol.101
, pp. 104-108
-
-
Sanders, P.W.1
-
42
-
-
0022448370
-
Glomerular blood flow after single nephron obstruction in the rat kidney
-
Tanner G.A., Knopp L.C. Glomerular blood flow after single nephron obstruction in the rat kidney. Am J Physiol 1986, 250(1 Pt 2):F77-F85.
-
(1986)
Am J Physiol
, vol.250
, Issue.1 PART 2
-
-
Tanner, G.A.1
Knopp, L.C.2
-
43
-
-
0024842905
-
Glomerular and proximal tubular morphology after single nephron obstruction
-
Tanner G.A., Evan A.P. Glomerular and proximal tubular morphology after single nephron obstruction. Kidney Int 1989, 36:1050-1060.
-
(1989)
Kidney Int
, vol.36
, pp. 1050-1060
-
-
Tanner, G.A.1
Evan, A.P.2
-
44
-
-
0026432631
-
Nephrotoxic potential of Bence Jones proteins
-
Solomon A., Weiss D.T., Kattine A.A. Nephrotoxic potential of Bence Jones proteins. N Engl J Med 1991, 324:1845-1851.
-
(1991)
N Engl J Med
, vol.324
, pp. 1845-1851
-
-
Solomon, A.1
Weiss, D.T.2
Kattine, A.A.3
-
45
-
-
0028208249
-
Pathogenic potential of human monoclonal immunoglobulin light chains: relationship of in vitro aggregation to in vivo organ deposition
-
Myatt E.A., Westholm F.A., Weiss D.T., Solomon A., Schiffer M., Stevens F.J. Pathogenic potential of human monoclonal immunoglobulin light chains: relationship of in vitro aggregation to in vivo organ deposition. Proc Natl Acad Sci USA 1994, 91:3034-3038.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3034-3038
-
-
Myatt, E.A.1
Westholm, F.A.2
Weiss, D.T.3
Solomon, A.4
Schiffer, M.5
Stevens, F.J.6
-
46
-
-
77954613992
-
Bortezomib successfully reduces monoclonal serum free light chain levels in a patient with recurrent myeloma and cast nephropathy in the renal transplant
-
Kumar V., Elkins S., Gaston R.S., et al. Bortezomib successfully reduces monoclonal serum free light chain levels in a patient with recurrent myeloma and cast nephropathy in the renal transplant. Clin Transpl 2009, 439-441.
-
(2009)
Clin Transpl
, pp. 439-441
-
-
Kumar, V.1
Elkins, S.2
Gaston, R.S.3
-
47
-
-
79951891171
-
Renal impairment in patients with multiple myeloma: a consensus statement on behalf of the International Myeloma Working Group
-
Dimopoulos M.A., Terpos E., Chanan-Khan A., et al. Renal impairment in patients with multiple myeloma: a consensus statement on behalf of the International Myeloma Working Group. J Clin Oncol 2010, 28:4976-4984.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4976-4984
-
-
Dimopoulos, M.A.1
Terpos, E.2
Chanan-Khan, A.3
-
48
-
-
77951880822
-
Renal recovery with lenalidomide in a patient with bortezomib-resistant multiple myeloma
-
Ludwig H., Zojer N. Renal recovery with lenalidomide in a patient with bortezomib-resistant multiple myeloma. Nat Rev Clin Oncol 2010, 7:289-294.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 289-294
-
-
Ludwig, H.1
Zojer, N.2
-
49
-
-
66449132961
-
Treatment of acute renal failure secondary to multiple myeloma with chemotherapy and extended high cut-off hemodialysis
-
Hutchison C.A., Bradwell A.R., Cook M., et al. Treatment of acute renal failure secondary to multiple myeloma with chemotherapy and extended high cut-off hemodialysis. Clin J Am Soc Nephrol 2009, 4:745-754.
-
(2009)
Clin J Am Soc Nephrol
, vol.4
, pp. 745-754
-
-
Hutchison, C.A.1
Bradwell, A.R.2
Cook, M.3
|