Correlates of potentially inappropriate prescriptions of benzodiazepines among older adults: Results from the ESA study

Canadian Journal on Aging

Volumn 31, Issue 3, 2012, Pages 313-322

  Préville, Michel ^a,b   Bossé, Cindy ^a   Vasiliadis, Helen Maria ^a,b   Voyer, Philippe ^c   Laurier, Claudine ^d   Berbiche, Djamal ^b   Pérodeau, Guiilhème ^b,e   Grenier, Sébastien ^b   Béland, Sarah Gabrielle ^d   Dionne, Pierre Alexandre ^a   Gentil, Lia ^a   Moride, Yola ^d  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

^b HÔPITAL CHARLES LEMOYNE   (Canada)

^c UNIVERSITÉ LAVAL   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e UNIVERSITÉ DU QUÉBEC EN OUTAOUAIS   (Canada)

Author keywords

aging; benzodiazepine use; epidemiology

Indexed keywords

BENZODIAZEPINE DERIVATIVE;

AGED; ARTICLE; CANADA; DRUG UTILIZATION; FEMALE; HUMAN; INAPPROPRIATE PRESCRIBING; INFORMATION PROCESSING; INSURANCE; MALE; PRESCRIPTION; PREVALENCE; STATISTICAL MODEL; STATISTICS;

AGED; AGED, 80 AND OVER; BENZODIAZEPINES; DATA COLLECTION; DRUG PRESCRIPTIONS; DRUG UTILIZATION; FEMALE; HUMANS; INAPPROPRIATE PRESCRIBING; INSURANCE CLAIM REVIEW; LOGISTIC MODELS; MALE; PREVALENCE; QUEBEC;

EID: 84865428530     PISSN: 07149808     EISSN: 17101107     Source Type: Journal    
DOI: 10.1017/S0714980812000232     Document Type: Review

References (53)

1. Aguilera, D.C. (1995). Intervention en situation de crise: Théorie et méthodologie [Crisis intervention: Theory and methodology]. Paris, France: InterEditions.
2. Allain, H., Bentue-Ferrer, D., Polard, E., Akwa, Y., & Patat, A. (2005). Postural instability and consequent falls and hip fractures associated with use of hypnotics in the elderly: A comparative review. Drugs and Aging, 22(9), 749-765.
3. American Psychiatric Association. (1994). Diagnostic and Statistical Manual of Mental Disorders DSM-IV. (4th Ed.). Washington, DC: American Psychiatric Association.
4. Ankri, J., Collin, J., Pérodeau, G., & Beaufils, B. (2002). Médicaments psychotropes et sujets âgés: une problématique commune France-Québec [Psychotropic drugs and elderly: the same problem in France and Quebec]. Sciences sociales et Santé, 20(1), 35-62.
5. Aparasu, R.R., Mort, J.R., & Brandt, H. (2003). Psychotropic prescription use by community-dwelling elderly in the United States. Journal of American Geriatrics Society, 51(5), 671-677.
6. Bartlett, G., Abrahamowicz, M., Tamblyn, R., Grad, R., Capek, R., & du Berger, R. (2004). Longitudinal patterns of new benzodiazepine use in the elderly. Pharmacoepide-miological Drug & Safety, 13(10), 669-682.
7. Ben Amar, M. (2007). La polyconsommation de psychotropes et les principales interactions pharmacologiques associées. [Poly-psychotropic drug use and its main associated pharmacological interactions ]Centre Québécois de lutte aux dépendances [Addiction prevention Center]. Comité permanent de lutte à la toxicomanie [Addiction prevention Committee], p. 30.
8. Bierman, E.J., Comijs, H.C., Gundy, C.M., Sonnenberg, C., Jonker, C., & Beekman, A.T. (2007). The effect of chronic benzodiazepine use on cognitive functioning in older persons: Good, bad or indifferent? International Journal of Geriatric Psychiatry, 22(12), 1194-1200.
9. Bolton, J.M., Metge, C., Lix, L., Prior, H., Sareen, J., & Leslie, W.D. (2008). Fracture risk from psychotropic medications: A population-based analysis. Journal of Clinical Psycho-pharmacology, 28(4), 384-391.
10. Chung, K.F., Cheung, R.C., & Tam, J.W. (1999). Long-term benzodiazepine users-characteristics, views and effectiveness of benzodiazepine reduction information leafl et. Singapore Medical Journal, 40(3), 138-143.
11. Collège des Médecins du Québec. (1997). L'utilisation prolongée des benzodiazépines [Long-term use of benzodi-azepines]. Le Collège; XXXVIL(3), 23. Retrieved from http://www.cmq.org/DocumentLibrary/Uploaded Contents/CmsDocuments/ lignesrecommandationbzd. pdf.
12. Conseil Consultatif de Pharmacologie. (1997). L'utilisation appropriée des benzodiazépines chez les personnes âgées [Appropriate use of benzodiazepines in older adults]. Info-médicament personnes âgées, Gouvernement du Québec, 7, 1-16.
13. Crum, R.M., Anthony, J.C., Basset, S.S., & Folstein, M.F. (1993). Population-based norms for the mini-mental state examination by age and educational level. Journal of American Medical Association, 269(18), 2386-2391.
14. Cumming, R.G., & Le Couteur, D.G. (2003). Benzodiazepines and risk of hip fractures in older people: A review of the evidence. Central Nervous System Drugs, 17(11), 825-837.
15. Dealberto, M.J., Seeman, T., McAvay, G.J., & Berkman, L. (1997). Factors related to current and subsequent psychotropic drug use in an elderly cohort. Journal of Clinical Epidemiology, 50(3), 357-364.
16. Egan, M., Moride, Y., Wolfson, C., & Monette, J. (2000). Longterm continuous use of benzodiazepines by older adults in Quebec: Prevalence, incidence and risk factors. Journal of American Geriatrics Society, 48(7), 811-816.
17. Fick, D.M., Waller, J.L., Maclean, J.R., Vanden Heuvel, R., Tadlock, J.G., Gottlieb, M., et al. (2001). Potentially inappropriate medication use in a medicare managed care population: Association with higher costs and utilization. Journal of Managing Care Pharmacology, 7(5), 407-413.
18. Gleason, P.P., Schulz, R., Smith, N.L., Newsom, J.T., Kroboth, P.D., Kroboth, F.J., et al. (1998). Correlates and prevalence of benzodiazepine use in community-dwelling elderly. Journal of General International Medicine, 13(4), 243-250.
19. Gray, S.L., LaCroix, A.Z., Blough, D., Wagner, E.H., Koepsell, T.D., & Buchner, D. (2002). Is the use of benzo-diazepines associated with incident disability? Journal of American Geriatrics Society, 50(6), 1012-1018.
20. Gray, S.L., LaCroix, A.Z., Hanlon, J.T., Penninx, B.W., Blough, D.K., Leveille, S.G., et al. (2006). Benzodiazepine use and physical disability in community-dwelling older adults. Journal of American Geriatrics Society, 54(2), 224-230.
21. Grymonpre, R.E., Mitenko, P.A., Sitar, D.S., Aoki, F.Y., & Montgomery, P.R. (1988). Drug-associated hospital admissions in older medical patients. Journal of American Geriatrics Society, 36(12), 1092-1098.
22. Hanlon, J.T., Schmader, K.E., Boult, C., Artz, M.B., Gross, C.R., Fillenbaum, G.G., et al. (2002). Use of inappropriate prescription drugs by older people. Journal of American Geriatrics Society, 50(1), 26-34.
23. Hosmer, D.W., & Lemeshow, S. (1989). Applied logistic regression. New York: John Wiley & Sons.
24. Institut de la Statistique du Québec. (2005). Lexique du système du code géographique du Québec [Glossary of the system of geographical codes in Quebec] Québec, Gouvernement du Québec.
25. Isacson, D. (1997). Long-term benzodiazepine use: Factors of importance and the development of individual use patterns over time-a 13-year follow-up in a Swedish community. Social Science in Medicine, 44(12), 1871-1880.
26. Kassam, A., & Patten, S.B. (2006). Canadian trends in benzo-diazepine and zopiclone use. Canadian Journal of Clinical Pharmacology, 13(1), 121-127.
27. Keri Yang, H.W., Simoni-Wastila, L., Zuckerman, I.H., & Stuart, B. (2008). Benzodiazepine use and expenditures for medicare benefi ciaries and the implications of medicare part D exclusions. Psychiatric Services, 59(4), 384-391.
28. Landi, F., Onder, G., Cesari, M., Barillaro, C., Russo, A., Bernabei, R., et al. (2005). Psychotropic medications and risk for falls among community-dwelling frail older people: An observational study. Journal of Gerontology Series A: Biological Sciences and Medical Sciences, 60(5), 622-626.
29. Lechevallier, N., Fourrier, A., & Berr, C. (2003). Utilisation de benzodiazépines chez le sujet âgé: données de la cohorte EVA [Use of benzodiazepines in older adults: Data from the EVA cohort]. Revue épidémiologique de Santé publique, 51(3), 317-326.
30. Luijendijk, H.J., Tiemeier, H., Hofman, A., Heeringa, J., & Stricker, B.H. (2008). Determinants of chronic benzodi-azepine use in the elderly: A longitudinal study. British Journal of Clinical Pharmacology, 65(4), 593-599.
31. McLeod, P.J., Huang, A.R., Tamblyn, R.M., & Gayton, D.C. (1997). Defi ning inappropriate practices in prescribing for elderly people: A national consensus panel. Canadian Medical Association Journal, 156(3), 385-391.
32. Morgan, K., Dallosso, H., Ebrahim, S., Arie, T., & Fentem, P.H. (1988). Prevalence, frequency, and duration of hypnotic drug use among the elderly living at home. British Medical Journal (Clinical Research Edition), 296(6622), 601-602.
33. Mort, J.R., & Aparasu, R.R. (2000). Prescribing potentially inappropriate psychotropic medications to the ambulatory elderly. Archives of Internal Medicine, 160(18), 2825-2831.
34. Panneman, M.J., Goettsch, W.G., Kramarz, P., & Herings, R.M. (2003). The costs of benzodiazepine-associated hospital-treated fall injuries in the EU: A Pharmo study. Drugs and Aging, 20(11), 833-839.
35. Pepper, G.A. (1999). Drug use and misuse. In J.T. Stone, J.F. Wyman, & S.A. Salisbury (Eds.), Clinical Gerontological Nursing, A Guide to Advanced Practice. Montréal, Quebec, Canada: Saunders.
36. Pérodeau, G., Jomphe Hill, A., Hay-Paquin, L., & Amyot, E. (1996). Les psychotropes et le vieillissement normal: une perspective psychosociale et socioéconomique [Psycho-tropic drugs and normal aging: A psychosocial and socioeconomic perspective]. Canadian Journal of Aging, 15(4), 559-582.
37. Préville, M., Boyer, R., Grenier, S., Dubé, M., Voyer, P., Punti, R., et al. (2008). The epidemiology of psychiatric disorders in Quebec's older adult population. Canadian Journal of Psychiatry, 53(12), 822-832.
38. Préville, M., Hébert, R., Boyer, R., & Bravo, G. (2001). Correlates of psychotropic drug use in the elderly compared to adults aged 18-64: Results from the Quebec Health Survey. Aging and Mental Health, 5(3), 216-224.
39. Rancourt, C., Moisan, J., Baillargeon, L., Verreault, R., Laurin, D., & Grégoire, J.P. (2004). Potentially inappropriate prescriptions for older patients in long-term care. BioMed Central Geriatrics, 4, 9.
40. Régie de l'assurance maladie du Québec (RAMQ). (2001). Portrait quotidien de la consommation médicamenteuse des personnes âgées non hébergées, Gouvernement du Québec. Retrieved from http://www.ramq.gouv.qc.ca/fr/publications/documents/ depliantscitoyens/consom. pdf.
41. Riska, E., & Klaukka, T. (1984). Use of psychotropic drugs in Finland. Social Science in Medicine, 19(9), 983-989.
42. Roberts, A.R. (2002). Assessment, crisis intervention, and trauma treatment: The integrative ACT intervention model. Brief Treatment in Crisis Intervention, 2(1), 1-21.
43. Robitaille, L., Courchesne, M., Sylvain, J., & Vadnais, M. (1991). Anxiolytiques et hypnotiques [Anxiolytics and hypnotics]. In G. Barbeau, J. Guimond, & L. Mallet (Eds.), Médicaments et personnes âgées (pp. 257-274). Canada: Edisem et Maloine.
44. Souchet, E., Lapeyre-Mestre, M., & Montastruc, J.L. (2005). Drug related falls: A study in the French pharmacovigi-lance database. Pharmacoepidemiology and Drug Safety, 14(1), 11-16.
45. Swartz, M., Landerman, R., George, L.K., Melville, M.L., Blazer, D., & Smith, K. (1991). Benzodiazepine anti-anxiety agents: Prevalence and correlates of use in a southern community. American Journal of Public Health, 81(5), 592-596.
46. Tamblyn, R. (1996). Medication use in seniors: Challenges and solutions. Therapy, 51(3), 269-282.
47. Tamblyn, R.M., McLeod, P.J., Abrahamowicz, M., Monette, J., Gayton, D.C., Berkson, L., et al. (1994). Questionable prescribing for elderly patients in Quebec. Canadian Medical Association Journal, 150(11), 1801-1809.
48. Tatro, D.S., & Hartshorn, E.A. (2001). Drug interaction facts on disc. St Louis, MO: Facts and Comparisons Inc.
49. Voyer, P., Cappeliez, P., Pérodeau, G., & Préville, M. (2005). Mental health for older adults and benzodiazpine use. Journal of Community Health Nursing, 22(4), 213-229.
50. Voyer, P., McCubbin, M., Cohen, D., Lauzon, S., Collin, J., & Boivin, C. (2004). Unconventional indicators of drug dependence among elderly long-term users of benzodi-azepines. Issues in Mental Health Nursing, 25(6), 603-628.
51. Voyer, P., Préville, M., Roussel, M.E., Berbiche, D., & Beland, S.G. (2009). Factors associated with benzodi-azepine dependence among community-dwelling seniors. Journal of Community Health Nursing, 26(3), 101-113.
52. Wagner, A.K., Zhang, F., Soumerai, S.B., Walker, A.M., Gurwitz, J.H., Glynn, R.J., et al. (2004). Benzodiazepine use and hip fractures in the elderly: Who is at greatest risk? Archives of Internal Medicine, 164(14), 1567-1572.
53. Woolcott, J.C., Richardson, K.J., Wiens, M.O., Patel, B., Marin, J., Khan, K.M., et al. (2009). Meta-analysis of the impact of 9 medication classes on falls in elderly persons. Archives of Internal Medicine, 169(21), 1952-1960.