A splice site mutation in Laminin-α2 results in a severe muscular dystrophy and growth abnormalities in Zebrafish

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Gupta, Vandana A ^a   Kawahara, Genri ^a   Myers, Jennifer A ^a   Chen, Aye T ^a   Hall, Thomas E ^b   Manzini, M Chiara ^a   Currie, Peter D ^b   Zhou, Yi ^a   Zon, Leonard I ^a,c   Kunkel, Louis M ^a   Beggs, Alan H ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b MONASH UNIVERSITY   (Australia)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LAMININ ALPHA2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SIZE; CELL DAMAGE; CONTROLLED STUDY; DISEASE SEVERITY; FRAMESHIFT MUTATION; GENE; GENE MAPPING; GENE MUTATION; GROWTH DISORDER; HETEROZYGOSITY; HOMOZYGOSITY; LAMA GENE; MOTOR PERFORMANCE; MUSCLE CELL; MUSCULAR DYSTROPHY; NONHUMAN; PATHOGENESIS; PHENOTYPE; PROTEIN DEPLETION; PROTEIN EXPRESSION; RNA SPLICING; SKELETAL MUSCLE; ZEBRA FISH;

ANIMALS; BASE SEQUENCE; EXTRACELLULAR MATRIX; HUMANS; LAMININ; MUSCLE FIBERS, SKELETAL; MUSCULAR DYSTROPHIES; MUTATION; RNA SPLICE SITES; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84865424405     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043794     Document Type: Article

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