Concentration-dependent cytotoxicity of copper ions on mouse fibroblasts in vitro: Effects of copper ion release from TCu380A vs TCu220C intra-uterine devices

Biomedical Microdevices

Volumn 14, Issue 4, 2012, Pages 709-720

  Cao, Bianmei ^a,d   Zheng, Yudong ^a   Xi, Tingfei ^a,b   Zhang, Chuanchuan ^b   Song, Wenhui ^c   Burugapalli, Krishna ^c   Yang, Huai ^a   Ma, Yanxuan ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY BEIJING   (China)

^b NATIONAL INSTITUTE FOR THE CONTROL OF PHARMACEUTICAL AND BIOLOGICAL PRODUCTS   (China)

^c BRUNEL UNIVERSITY   (United Kingdom)

^d Beijing Institute of Medical Device Testing   (China)

Author keywords

Cell behavior; Copper; Intrauterine devices; Material cell interactions

Indexed keywords

96-WELL PLATE; APOPTOTIC CELLS; BURST RELEASE; CELL BEHAVIORS; CELL CYCLE; CELL CYCLE ANALYSIS; CELL DIVISIONS; CELL SEEDING; CELL SEEDING DENSITY; CELL VIABILITY; CONCENTRATION-DEPENDENT; COPPER IONS; CU IONS; CU SURFACES; CULTURE MEDIA; CULTURE TIME; CYTOTOXIC; CYTOTOXIC EFFECTS; CYTOTOXICITY ASSAYS; FUNCTION OF TIME; H-BASED; IN-VITRO; INTRA-UTERINE DEVICES; ION CONCENTRATIONS; ION TOXICITY; ION TREATMENT; LETHAL CONCENTRATION; MOUSE-FIBROBLASTS; SUSTAINED RELEASE; TISSUE CULTURE PLATES;

ASSAYS; BROMINE COMPOUNDS; CELL DEATH; CELL PROLIFERATION; CONCENTRATION (PROCESS); COPPER; CYTOTOXICITY; FIBROBLASTS; MAMMALS; METAL IONS; TISSUE; TISSUE CULTURE; TOXICITY;

HEAVY IONS;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; COPPER ION;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL CULTURE; CELL DENSITY; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTACT INHIBITION; CONTRACEPTION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; FIBROBLAST; IN VITRO STUDY; INTRAUTERINE CONTRACEPTIVE DEVICE; ION TRANSPORT; MICROSCOPY; MITOSIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TISSUE CULTURE; TREATMENT RESPONSE;

ANIMALS; ANNEXIN A5; APOPTOSIS; CELL CYCLE; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; INTRAUTERINE DEVICES; MICE; PROPIDIUM; TIME FACTORS;

EID: 84865417106     PISSN: 13872176     EISSN: 15728781     Source Type: Journal    
DOI: 10.1007/s10544-012-9651-x     Document Type: Article

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