A novel automated bioreactor for scalable process optimisation of haematopoietic stem cell culture

Journal of Biotechnology

Volumn 161, Issue 3, 2012, Pages 387-390

  Ratcliffe, E ^a   Glen, K E ^a   Workman, V L ^a   Stacey, A J ^b   Thomas, R J ^a  

^a LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^b SARTORIUS STEDIM BIOTECH GMBH   (Germany)

Author keywords

; Ambr ; ANOVA; Bioreactor; Cell culture automation; DO2; EPO; FITC; Haematopoietic stem cells; HSCs; IGF 1; IL 3; Process development; Rpm; SCF; SEM; Suspension culture

Indexed keywords

DO2; EPO; FITC; HAEMATOPOIETIC STEM CELLS; HSCS; IGF-1; IL-3; PROCESS DEVELOPMENT; RPM; SCF; SUSPENSION CULTURES;

ANALYSIS OF VARIANCE (ANOVA); AUTOMATION; BLOOD; CELL CULTURE; CELL PROLIFERATION; MANUFACTURE; OPTIMIZATION; SCANNING ELECTRON MICROSCOPY; STEM CELLS;

BIOREACTORS;

ARTICLE; BIOREACTOR; BIOREACTOR EQUIPMENT; CELL DENSITY; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; ERYTHROID CELL; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; OXYGEN TENSION; PRIORITY JOURNAL; PROCESS CONTROL; PROCESS MONITORING; PROCESS OPTIMIZATION; SUSPENSION CELL CULTURE;

AUTOMATION; BIOREACTORS; CELL COUNT; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; HEMATOPOIETIC STEM CELLS; HUMANS; OXYGEN;

EID: 84865414297     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2012.06.025     Document Type: Article

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