Novel inhibitors of hepatitis C virus RNA-dependent RNA polymerases

Journal of Molecular Biology

Volumn 357, Issue 4, 2006, Pages 1051-1057

  Lee, Gary ^a   Piper, Derek E ^a   Wang, Zhulun ^a   Anzola, John ^a   Powers, Jay ^a   Walker, Nigel ^a   Li, Yang ^a  

^a AMGEN INC   (United States)

Author keywords

HCV; Inhibitor; NS5B; RNA dependent RNA polymerase; Structure

Indexed keywords

5 (4 BROMOPHENYL METHYLENE) 3 (BENZENESULFONYLAMINO) 4 OXXO 2 THIONOTHIAZOLIDINE; 5 (4 CHLOROPHENYLMETHYLENE) 3 (BENZENESULFONYLAMINO) 4 OXXO 2 THIONOTHIAZOLIDINE; BENZYLIDENE DERIVATIVE; CYSTEINE; ENZYME INHIBITOR; NUCLEOTIDE; RNA DIRECTED RNA POLYMERASE; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CHRONIC HEPATITIS; ENZYME ACTIVITY; ENZYME INHIBITION; GENOTYPE; HEPATITIS C VIRUS; IC 50; IN VITRO STUDY; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; VIRUS RESISTANCE;

HEPATITIS C VIRUS;

EID: 33644826759     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.01.032     Document Type: Article

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