Effects of low doses of estrone on the proliferation, differentiation and mineralization of osteoprecursor cells

Experimental and Therapeutic Medicine

Volumn 4, Issue 4, 2012, Pages 681-684

  Park, Jun Beom ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Differentiation; Estrogen receptor ; Estrogen receptor ; Estrone; Osteoblast; Osteopontin; Proliferation

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALIZARIN RED S; ALKALINE PHOSPHATASE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTRONE; OSTEOPONTIN;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; BONE MINERALIZATION; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; LOW DRUG DOSE; NONHUMAN; OSSIFICATION; PROTEIN EXPRESSION;

EID: 84865398004     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2012.655     Document Type: Article

References (17)

1. Dechering K, Boersma C and Mosselman S: Estrogen receptors alpha and beta: two receptors of a kind? Curr Med Chem 7: 561-576, 2000.
2. Syed F and Khosla S: Mechanisms of sex steroid effects on bone. Biochem Biophys Res Commun 328: 688-696, 2005.
3. Wang Y, Li LZ, Zhang YL, Zhu YQ, Wu J and Sun WJ: LC, a novel estrone-rhein hybrid compound, concurrently stimulates osteoprotegerin and inhibits receptor activator of NF-kappaB ligand (RANKL) and interleukin-6 production by human osteoblastic cells. MolCellEndocrinol337: 43-51, 2011.
4. López-Marcos JF, García-Valle S and García-Iglesias AA: Periodontal aspects in menopausal women undergoing hormone replacement therapy. MedOralPatolOralCirBucal 10: 132-141, 2005 (In English and Spanish).
5. Tarakji B, Nassani MZ and Sloan P: Immunohistochemical expression of estrogens and progesterone receptors in carcinoma ex pleomorphic adenoma-undifferentiated and adenocarcinoma types. MedOralPatolOralCirBucal15: e432-e436, 2010.
6. Coelingh Bennink HJ: Are all estrogens the same? Maturitas47: 269-275, 2004.
7. Qu Q, Perälä-Heape M, Kapanen A, et al: Estrogen enhances differentiation of osteoblasts in mouse bone marrow culture. Bone22: 201-209, 1998.
8. Wang Y, Li LZ, Zhang YL, et al: LC, a novel estrone-rhein hybrid compound, promotes proliferation and differentiation and protects against cell death in human osteoblastic MG-63 cells. Mol Cell Endocrinol 344: 59-68, 2011.
9. Park JB: Effects of fibroblast growth factor 2 on osteoblastic proliferation and differentiation by regulating bone morphogenetic protein receptor expression. JCraniofac Surg 22: 1880-1882, 2011.
10. Odabaş ME, Ertürk M, Çinar Ç, Tuzüner T and Tulunoǧlu Ö: Cytotoxicity of a new hemostatic agent on human pulp fibroblasts in vitro. Med Oral Patol Oral Cir Bucal 16: e584-e587, 2011.
11. Luo XH and Liao EY: Effects of estriol on the proliferation and differentiation of human osteoblastic MG-63 cells. Endocr Res 29: 343-351, 2003.
12. Park JB: The effects of dexamethasone, ascorbic acid, and beta-glycerophosphate on osteoblastic differentiation by regulating estrogen receptor and osteopontin expression. J Surg Res 173: 99-104, 2012.
13. Todorovic T, Dozic I, Vicente-Barrero M, et al: Salivary enzymes and periodontal disease. MedOralPatolOralCir Bucal 11: E115-E119, 2006 (In Spanish and English).
14. Fernández-Tresguerres-Hernández-Gil I, Alobera-Gracia MA, del-Canto-Pingarrón M and Blanco-Jerez L: Physiological bases of bone regeneration. I. Histology and physiology of bone tissue. Med Oral Patol Oral Cir Bucal 11: E47-E51, 2006 (In English and Spanish).
15. Park JB: Effects of doxycycline, minocycline, and tetracycline on cell proliferation, differentiation, and protein expression in osteoprecursor cells. JCraniofacSurg22: 1839-1842, 2011.
16. Pinzone JJ, Stevenson H, Strobl JS and Berg PE: Molecular and cellular determinants of estrogen receptor alpha expression. MolCellBiol24: 4605-4612, 2004.
17. Huang W, Carlsen B, Rudkin G, et al: Osteopontin is a negative regulator of proliferation and differentiation in MC3T3-E1 pre-osteoblastic cells. Bone34: 799-808, 2004.