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Volumn 904, Issue , 2012, Pages 107-114
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Simultaneous quantification of niacin and its three main metabolites in human plasma by LC-MS/MS
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Author keywords
N methyl 2 pyridone 5 carboxamide; Niacin; Nicotinamide; Nicotinuric acid; Pharmacokinetics
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Indexed keywords
ANALYTES;
BIOANALYTICAL METHODS;
CALIBRATION CURVES;
CONCENTRATION RANGES;
DEPROTEINIZATION;
HUMAN PLASMAS;
ISOCRATIC ELUTION;
LC-MS/MS;
MULTIPLE REACTION MONITORING;
N-METHYL-2-PYRIDONE-5-CARBOXAMIDE;
NIACIN;
NICOTINAMIDE;
ORAL DOSE;
PLASMA SAMPLES;
POSITIVE ELECTROSPRAY IONIZATION;
SIMVASTATIN;
ACETONITRILE;
AMIDES;
BIOMOLECULES;
CENTRIFUGATION;
COLUMN CHROMATOGRAPHY;
ELECTROSPRAY IONIZATION;
FORMIC ACID;
METABOLITES;
METHANOL;
PHARMACOKINETICS;
PYRIDINE;
PLASMA (HUMAN);
ACETONITRILE;
N METHYL 2 PYRIDONE 5 CARBOXAMIDE;
NICOTINAMIDE;
NICOTINIC ACID;
NICOTINIC ACID PLUS SIMVASTATIN;
NICOTINURIC ACID;
OXIRACETAM;
UNCLASSIFIED DRUG;
ADULT;
AGED;
ARTICLE;
CALIBRATION;
CENTRIFUGATION;
CHINESE;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
ELECTROSPRAY;
EVAPORATION;
FEMALE;
HUMAN;
HUMAN EXPERIMENT;
LIQUID CHROMATOGRAPHY;
MALE;
NORMAL HUMAN;
PRIORITY JOURNAL;
QUANTITATIVE ANALYSIS;
SINGLE DRUG DOSE;
SUSTAINED RELEASE FORMULATION;
TANDEM MASS SPECTROMETRY;
VALIDATION STUDY;
ADULT;
CHROMATOGRAPHY, LIQUID;
DELAYED-ACTION PREPARATIONS;
DRUG STABILITY;
FEMALE;
HUMANS;
LINEAR MODELS;
MALE;
NIACIN;
NICOTINIC ACIDS;
PYRIDONES;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
TANDEM MASS SPECTROMETRY;
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EID: 84865395801
PISSN: 15700232
EISSN: 1873376X
Source Type: Journal
DOI: 10.1016/j.jchromb.2012.07.030 Document Type: Article |
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Times cited : (22)
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References (27)
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