Dynamics of the primary cilium in shear flow

Biophysical Journal

Volumn 103, Issue 4, 2012, Pages 629-639

  Young, Y N ^a   Downs, M ^b   Jacobs, C R ^b  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

^b Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIOMECHANICS; CYTOLOGY; ELASTICITY; EPITHELIUM CELL; EUKARYOTIC FLAGELLUM; HYDRODYNAMICS; MECHANICS; METABOLISM;

ANIMALS; BIOMECHANICS; CILIA; ELASTICITY; EPITHELIAL CELLS; HYDRODYNAMICS; MECHANICAL PROCESSES; MODELS, BIOLOGICAL;

EID: 84865385190     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2012.07.009     Document Type: Article

References (40)

1. R.A. Bloodgood From central to rudimentary to primary: the history of an underappreciated organelle whose time has come. The primary cilium R.D. Sloboda, Methods in Cell Biology, Vol. 94: Primary Cilia 2009 Academic Press San Diego, CA 3 52
2. P. Satir, L.B. Pedersen, and S.T. Christensen The primary cilium at a glance J. Cell Sci. 123 2010 499 503
3. E.S. Seeley, and M.V. Nachury Constructing and deconstructing roles for the primary cilium in tissue architecture and cancer R.D. Sloboda, Methods in Cell Biology, Vol. 94: Primary Cilia 2009 Academic Press San Diego, CA 300 311
4. H. Hagiwara, and A. Kano N. Ohwada Immunocytochemistry of the striated rootlets associated with solitary cilia in human oviductal secretory cells Histochem. Cell Biol. 114 2000 205 212
5. H. Ishikawa, and W.F. Marshall Ciliogenesis: building the cell's antenna Nat. Rev. Mol. Cell Biol. 12 2011 222 234
6. R. Rohatgi, and W.J. Snell The ciliary membrane Curr. Opin. Cell Biol. 22 2010 541 546
7. R.Y. Kwon, D.A. Hoey, and C.R. Jacobs Mechanobiology of Primary Cilia A. Gefen, Cellular and Biomolecular Mechanics and Mechanobiology 2011 Springer NJ 99 124
8. J.R. Marszalek, and P. Ruiz-Lozano L.S. Goldstein Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II Proc. Natl. Acad. Sci. USA 96 1999 5043 5048 (Pubitemid 29214532)
9. C.J. Haycraft, and R. Serra Cilia involvement in patterning and maintenance of the skeleton Curr. Top. Dev. Biol. 85 2008 303 332
10. H.W. Ehlen, L.A. Buelens, and A. Vortkamp Hedgehog signaling in skeletal development Birth Defects Res. C Embryo Today 78 2006 267 279
11. H.A. Praetorius, and K.R. Spring Bending the MDCK cell primary cilium increases intracellular calcium J. Membr. Biol. 184 2001 71 79 (Pubitemid 33016173)
12. H.A. Praetorius, and K.R. Spring Removal of the MDCK cell primary cilium abolishes flow sensing J. Membr. Biol. 191 2003 69 76 (Pubitemid 37011467)
13. E.J. Arnsdorf, P. Tummala, and C.R. Jacobs Non-canonical Wnt signaling and N-cadherin related β-catenin signaling play a role in mechanically induced osteogenic cell fate PLoS ONE 4 2009 e5388
14. S.M. Nauli, and F.J. Alenghat J. Zhou Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells Nat. Genet. 33 2003 129 137 (Pubitemid 36177063)
15. 2+ and cAMP signaling Gastroenterology 131 2006 911 920 (Pubitemid 44307075)
16. E.A. Schwartz, and M.L. Leonard S.S. Bowser Analysis and modeling of the primary cilium bending response to fluid shear Am. J. Physiol. 272 1997 F132 F138
17. A. Resnick, and U. Hopfer Mechanical stimulation of primary cilia Front. Biosci. 13 2008 1665 1680 (Pubitemid 351611609)
18. 2+ concentration is attenuated in collecting duct of monocilium-impaired Orpk mice Am. J. Physiol. Renal Physiol. 289 2005 F978 F988
19. S. Rydholm, and G. Zwartz H. Brismar Mechanical properties of primary cilia regulate the response to fluid flow Am. J. Physiol. Renal Physiol. 298 2010 F1096 F1102
20. A.-K. Tornberg, and M.J. Shelley Simulating the dynamics and interactions of flexible fibers in stokes flows J. Comput. Phys. 196 2004 8 40 (Pubitemid 38521660)
21. C.H. Wiggins, and D. Riveline R.E. Goldstein Trapping and wiggling: elastohydrodynamics of driven microfilaments Biophys. J. 74 1998 1043 1060 (Pubitemid 28345299)
22. C.H. Wiggins Biopolymer mechanics: stability, dynamics and statistics Math. Methods Appl. Sci. 24 2001 1325 1335 (Pubitemid 34124819)
23. T. Munk, and O. Hallatschek E. Frey Dynamics of semiflexible polymers in a flow field Phys. Rev. E Stat. Nonlin. Soft Matter Phys. 74 2006 041911
24. C. Pozrikidis Introduction to Theoretical and Computational Fluid Dynamics 1997 Oxford University Press New York
25. R.E. Johnson, and C.J. Brokaw Flagellar hydrodynamics. A comparison between resistive-force theory and slender-body theory Biophys. J. 25 1979 113 127 (Pubitemid 9107850)
26. Y.-N. Young Hydrodynamic interactions between two semiflexible inextensible filaments in Stokes flow Phys. Rev. E. 79 2009 046317
27. C. Pozrikidis Shear flow over cylindrical rods attached to a substrate Fluids Struct. 26 2010 393 405
28. C. Pozrikidis Shear flow past slender elastic rods attached to a plane Int. J. Solids Struct. 48 2011 137 143
29. S. Gueron, and N. Liron Ciliary motion modeling, and dynamic multicilia interactions Biophys. J. 63 1992 1045 1058
30. S. Gueron, and K. Levit-Gurevich A three-dimensional model for ciliary motion based on the internal 9+2 structure Proc. Biol. Sci. 268 2001 599 607 (Pubitemid 32269848)
31. M.E. Downs, and A.M. Nguyen C.R. Jacobs An experimental and computational analysis of primary cilia deflection under fluid flow Comput. Methods Biomech. Biomed. Engin. 2011 10.1080/10255842.2011.653784
32. N.F. Berbari, and A.D. Johnson K. Mykytyn Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors Mol. Biol. Cell 19 2008 1540 1547 (Pubitemid 351805107)
33. B. Ruhfus, H.G. Bauernschmitt, and R.K.H. Kinne Properties of a polarized primary culture from rat renal inner medullary collecting duct (IMCD) cells In Vitro Cell. Dev. Biol. Anim. 34 1998 227 231 (Pubitemid 29077075)
34. T.L.H. Donahue, and T.R. Haut C.R. Jacobs Mechanosensitivity of bone cells to oscillating fluid flow induced shear stress may be modulated by chemotransport J. Biomech. 36 2003 1363 1371 (Pubitemid 36951999)
35. R.G. Bacabac, and T.H. Smit J. Klein-Nulend Dynamic shear stress in parallel-plate flow chambers J. Biomech. 38 2005 159 167 (Pubitemid 39424990)
36. K.R. Schumacher, and A.S. Popel A.A. Spector Modeling the mechanics of tethers pulled from the cochlear outer hair cell membrane J. Biomech. Eng. 130 2008 031007
37. K.R. Schumacher, and A.S. Popel A.A. Spector Computational analysis of the tether-pulling experiment to probe plasma membrane-cytoskeleton interaction in cells Phys. Rev. E. 80 2009 041905
38. E. Perozo, and A. Kloda B. Martinac Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating Nat. Struct. Biol. 9 2002 696 703 (Pubitemid 34977304)
39. P. Wiggins, and R. Phillips Analytic models for mechanotransduction: gating a mechanosensitive channel Proc. Natl. Acad. Sci. USA 101 2004 4071 4076 (Pubitemid 38405885)
40. R. Phillips, J. Kondev, and J. Theriot Physical Biology of the Cell 2009 Garland Science New York