메뉴 건너뛰기




Volumn 38, Issue 5, 2012, Pages 1003-1011

Pharmacological augmentation strategies for schizophrenia patients with insufficient response to clozapine: A quantitative literature review

Author keywords

augmentation; clozapine; resistant; schizophrenia

Indexed keywords

6 QUINOXALINECARBOXYLIC ACID PIPERIDIDE; AMISULPRIDE; ARIPIPRAZOLE; CITALOPRAM; CLOZAPINE; CYCLOSERINE; FLUOXETINE; GLYCINE; HALOPERIDOL; LAMOTRIGINE; MIRTAZAPINE; PLACEBO; RISPERIDONE; SARCOSINE; SERINE; SULPIRIDE; TOPIRAMATE;

EID: 84865334678     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbr004     Document Type: Article
Times cited : (128)

References (80)
  • 1
    • 0030689616 scopus 로고    scopus 로고
    • Evaluation of treatment-resistant schizophrenia
    • Conley RR, Buchanan RW. Evaluation of treatment-resistant schizophrenia. Schizophr Bull. 1997;23:663-674.
    • (1997) Schizophr Bull , vol.23 , pp. 663-674
    • Conley, R.R.1    Buchanan, R.W.2
  • 2
    • 0024242021 scopus 로고
    • A selective review of recent North American long-term followup studies of schizophrenia
    • McGlashan TH. A selective review of recent North American long-term followup studies of schizophrenia. Schizophr Bull. 1988;14:515-542.
    • (1988) Schizophr Bull , vol.14 , pp. 515-542
    • McGlashan, T.H.1
  • 3
    • 0024995710 scopus 로고
    • Economic grand rounds: Cost-effectiveness of clozapine for treatment-resistant schizophrenic patients
    • Revicki DA, Luce BR, Weschler JM, Brown RE, Adler MA. Economic grand rounds: cost-effectiveness of clozapine for treatment-resistant schizophrenic patients. Hosp Community Psychiatry. 1990;41:850-854.
    • (1990) Hosp Community Psychiatry , vol.41 , pp. 850-854
    • Revicki, D.A.1    Luce, B.R.2    Weschler, J.M.3    Brown, R.E.4    Adler, M.A.5
  • 5
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine
    • Kane J, Honigfeld G, Singer J, Meltzer H. Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Arch Gen Psychiatry. 1988;5:789-796.
    • (1988) Arch Gen Psychiatry , vol.5 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3    Meltzer, H.4
  • 6
    • 0035065899 scopus 로고    scopus 로고
    • Effectiveness of second-generation antipsychotics in patients with treatment-resistant schizophrenia: A review and meta-analysis of randomized trials
    • Chakos M, Lieberman J, Hoffman E, Bradford D, Sheitman B. Effectiveness of second-generation antipsychotics in patients with treatment-resistant schizophrenia: a review and meta-analysis of randomized trials. Am J Psychiatry. 2001;158:518-526.
    • (2001) Am J Psychiatry , vol.158 , pp. 518-526
    • Chakos, M.1    Lieberman, J.2    Hoffman, E.3    Bradford, D.4    Sheitman, B.5
  • 7
    • 33748768220 scopus 로고    scopus 로고
    • Randomized controlled trial of effect of prescription of clozapine versus other second-generation antipsychotic drugs in resistant schizophrenia
    • Lewis SW, Barnes TRE, Davies L, et al. Randomized controlled trial of effect of prescription of clozapine versus other second-generation antipsychotic drugs in resistant schizophrenia. Schizophr Bull. 2006;32:715-723.
    • (2006) Schizophr Bull , vol.32 , pp. 715-723
    • Lewis, S.W.1    Barnes, T.R.E.2    Davies, L.3
  • 8
    • 85047698267 scopus 로고    scopus 로고
    • Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment
    • McEvoy JP, Lieberman JA, Stroup TS, et al. Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment. Am J Psychiatry. 2006;163:600-610.
    • (2006) Am J Psychiatry , vol.163 , pp. 600-610
    • McEvoy, J.P.1    Lieberman, J.A.2    Stroup, T.S.3
  • 9
    • 0043205845 scopus 로고    scopus 로고
    • What is an adequate trial with clozapine?
    • Schulte PFJ. What is an adequate trial with clozapine? Clin Pharmacokinet. 2003;42:607-618.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 607-618
    • Schulte, P.F.J.1
  • 10
    • 0028007550 scopus 로고
    • Clinical effects of clozapine in chronic schizophrenia: Response to treatment and predictors of outcome
    • Lieberman JA, Safferman AZ, Pollack S, et al. Clinical effects of clozapine in chronic schizophrenia: response to treatment and predictors of outcome. Am J Psychiatry. 1994;151: 1744-1752.
    • (1994) Am J Psychiatry , vol.151 , pp. 1744-1752
    • Lieberman, J.A.1    Safferman, A.Z.2    Pollack, S.3
  • 12
    • 0035060791 scopus 로고    scopus 로고
    • Double-blind comparison of olanzapine versus clozapine in schizophrenic patients eligible for treatment with clozapine
    • Lilly Resistant Schizophrenia Study Group
    • Tollefson GD, Birkett MA, Kiesler GM, Wood AJ. Lilly Resistant Schizophrenia Study Group. Double-blind comparison of olanzapine versus clozapine in schizophrenic patients eligible for treatment with clozapine. Biol Psychiatry. 2001; 49:59-60.
    • (2001) Biol Psychiatry , vol.49 , pp. 59-60
    • Tollefson, G.D.1    Birkett, M.A.2    Kiesler, G.M.3    Wood, A.J.4
  • 13
    • 0034674724 scopus 로고    scopus 로고
    • Cognitive behavioural psychotherapy for schizophrenia: A review of recent empirical studies
    • Dickerson FB. Cognitive behavioural psychotherapy for schizophrenia: a review of recent empirical studies. Schizophr Res. 2000;43:71-90.
    • (2000) Schizophr Res , vol.43 , pp. 71-90
    • Dickerson, F.B.1
  • 15
    • 77955297524 scopus 로고    scopus 로고
    • Should we expand the toolbox of psychiatric treatment methods to include Repetitive Transcranial Magnetic Stimulation (rTMS)? A meta-analysis of the efficacy of rTMS in psychiatric disorders
    • Slotema CW, Blom JD, Hoek HW, Sommer IE. Should we expand the toolbox of psychiatric treatment methods to include Repetitive Transcranial Magnetic Stimulation (rTMS)? A meta-analysis of the efficacy of rTMS in psychiatric disorders. J Clin Psychiatry. 2010;71:873-884.
    • (2010) J Clin Psychiatry , vol.71 , pp. 873-884
    • Slotema, C.W.1    Blom, J.D.2    Hoek, H.W.3    Sommer, I.E.4
  • 17
    • 32044435123 scopus 로고    scopus 로고
    • The choice of drugs for schizophrenia
    • Davis JM. The choice of drugs for schizophrenia. N Engl J Med. 2006;354:518-520.
    • (2006) N Engl J Med , vol.354 , pp. 518-520
    • Davis, J.M.1
  • 18
    • 34147137079 scopus 로고    scopus 로고
    • Risperidone augmentation for schizophrenia partially responsive to clozapine: A double-blind, placebocontrolled trial
    • Freudenreich O, Henderson DC, Walsh JP, Culhane MA, Goff DC. Risperidone augmentation for schizophrenia partially responsive to clozapine: a double-blind, placebocontrolled trial. Schizophr Res. 2007;92:90-94.
    • (2007) Schizophr Res , vol.92 , pp. 90-94
    • Freudenreich, O.1    Henderson, D.C.2    Walsh, J.P.3    Culhane, M.A.4    Goff, D.C.5
  • 19
    • 32044464964 scopus 로고    scopus 로고
    • Clozapine alone versus clozapine and risperidone with refractory schizophrenia
    • Honer WG, Thornton AE, Chen EY, et al. Clozapine alone versus clozapine and risperidone with refractory schizophrenia. N Engl J Med. 2006;354:472-482.
    • (2006) N Engl J Med , vol.354 , pp. 472-482
    • Honer, W.G.1    Thornton, A.E.2    Chen, E.Y.3
  • 20
    • 34247156726 scopus 로고    scopus 로고
    • Augmentation with a second antipsychotic in patients with schizophrenia who partially respond to clozapine: A meta-analysis
    • Paton C, Whittington C, Barnes TR. Augmentation with a second antipsychotic in patients with schizophrenia who partially respond to clozapine: a meta-analysis. J Clin Psychopharmacol. 2007;27:198-204.
    • (2007) J Clin Psychopharmacol , vol.27 , pp. 198-204
    • Paton, C.1    Whittington, C.2    Barnes, T.R.3
  • 21
    • 33947273551 scopus 로고    scopus 로고
    • Prevalence utilization patterns and predictors of antipsychotic polypharmacy: Experience in a multistate Medicaid population 1998-2003
    • Morrato EH, Dodd S, Oderda G, Haxby DG, Allen R, Valuck RJ. Prevalence, utilization patterns, and predictors of antipsychotic polypharmacy: experience in a multistate Medicaid population, 1998-2003. Clin Ther. 2007;29:183-195.
    • (2007) Clin Ther , vol.29 , pp. 183-195
    • Morrato, E.H.1    Dodd, S.2    Oderda, G.3    Haxby, D.G.4    Allen, R.5    Valuck, R.J.6
  • 22
    • 0029743798 scopus 로고    scopus 로고
    • Risperidone as an adjunct to clozapine therapy in chronic schizophrenics
    • Henderson DC, Goff DC. Risperidone as an adjunct to clozapine therapy in chronic schizophrenics. J Clin Psychiatry. 1996;57:395-397.
    • (1996) J Clin Psychiatry , vol.57 , pp. 395-397
    • Henderson, D.C.1    Goff, D.C.2
  • 23
    • 0030691937 scopus 로고    scopus 로고
    • Sulpiride augmentation in people with schizophrenia partially responsive to clozapine. A double-blind, placebo-controlled study
    • Shiloh R, Zemishlany Z, Aizenberg D, et al. Sulpiride augmentation in people with schizophrenia partially responsive to clozapine. A double-blind, placebo-controlled study. Br J Psychiatry. 1997;171:569-573.
    • (1997) Br J Psychiatry , vol.171 , pp. 569-573
    • Shiloh, R.1    Zemishlany, Z.2    Aizenberg, D.3
  • 24
    • 0029903904 scopus 로고    scopus 로고
    • Fluoxetine augmentation of clozapine treatment in patients with schizophrenia
    • Buchanan RW, Kirkpatrick B, Bryant N, Ball P, Breier A. Fluoxetine augmentation of clozapine treatment in patients with schizophrenia. Am J Psychiatry. 1996;153:1625-1627.
    • (1996) Am J Psychiatry , vol.153 , pp. 1625-1627
    • Buchanan, R.W.1    Kirkpatrick, B.2    Bryant, N.3    Ball, P.4    Breier, A.5
  • 25
    • 0030273281 scopus 로고    scopus 로고
    • Fluvoxamine augmentation in clozapine-resistant schizophrenia: An open pilot study
    • Silver H, Kushnir M, Kaplan A. Fluvoxamine augmentation in clozapine-resistant schizophrenia: an open pilot study. Biol Psychiatry. 1996;40:671-674.
    • (1996) Biol Psychiatry , vol.40 , pp. 671-674
    • Silver, H.1    Kushnir, M.2    Kaplan, A.3
  • 26
    • 0038722347 scopus 로고    scopus 로고
    • Tolerability and efficacy of clozapine combined with lithium in schizophrenia and schizoaffective disorder
    • Small JG, Klapper MH, Malloy FW, Steadman TM. Tolerability and efficacy of clozapine combined with lithium in schizophrenia and schizoaffective disorder. J Clin Psychopharmacol. 2003;23:223-228.
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 223-228
    • Small, J.G.1    Klapper, M.H.2    Malloy, F.W.3    Steadman, T.M.4
  • 27
    • 0028070783 scopus 로고
    • Concurrent use of clozapine and valproate in affective and psychotic disorders
    • Kando JC, Tohen M, Castillo J, Centorrino F. Concurrent use of clozapine and valproate in affective and psychotic disorders. J Clin Psychiatry. 1994;55:255-257.
    • (1994) J Clin Psychiatry , vol.55 , pp. 255-257
    • Kando, J.C.1    Tohen, M.2    Castillo, J.3    Centorrino, F.4
  • 28
    • 0027000622 scopus 로고
    • The use of carbamazepine in the treatment of schizophrenic and schizoaffective psychosis: A review
    • Simhandl C, Meszaros K. The use of carbamazepine in the treatment of schizophrenic and schizoaffective psychosis: a review. J Psychiatry Neurosci. 1992;17:1-14.
    • (1992) J Psychiatry Neurosci , vol.17 , pp. 1-14
    • Simhandl, C.1    Meszaros, K.2
  • 29
    • 0142095347 scopus 로고    scopus 로고
    • Lamotrigine in treatment-resistant schizophrenia: A randomized placebocontrolled crossover trial
    • Tiihonen J, Hallikainen T, Ryynanen OP, et al. Lamotrigine in treatment-resistant schizophrenia: a randomized placebocontrolled crossover trial. Biol Psychiatry. 2003;54:1241-1248.
    • (2003) Biol Psychiatry , vol.54 , pp. 1241-1248
    • Tiihonen, J.1    Hallikainen, T.2    Ryynanen, O.P.3
  • 30
    • 0029828805 scopus 로고    scopus 로고
    • Bromocriptine as adjunctive therapy to clozapine in treatment-resistant schizophrenia
    • Al-Semaan Y. Bromocriptine as adjunctive therapy to clozapine in treatment-resistant schizophrenia. Can J Psychiatry. 1996;41:484-485.
    • (1996) Can J Psychiatry , vol.41 , pp. 484-485
    • Al-Semaan, Y.1
  • 33
    • 0036140127 scopus 로고    scopus 로고
    • E-E Multicentre Study Group. A dose-ranging exploratory study of the effects of ethyleicosapentaenoate in patients with persistent schizophrenic symptoms
    • Peet M, Horrobin DF. E-E Multicentre Study Group. A dose-ranging exploratory study of the effects of ethyleicosapentaenoate in patients with persistent schizophrenic symptoms. J Psychiatr Res. 2002;36:7-18.
    • (2002) J Psychiatr Res , vol.36 , pp. 7-18
    • Peet, M.1    Horrobin, D.F.2
  • 34
    • 0033931444 scopus 로고    scopus 로고
    • Clozapine augmentation: Safety and efficacy
    • Chong SA, Remington G. Clozapine augmentation: safety and efficacy. Schizophr Bull. 2000;26:421-440.
    • (2000) Schizophr Bull , vol.26 , pp. 421-440
    • Chong, S.A.1    Remington, G.2
  • 35
    • 0346734341 scopus 로고    scopus 로고
    • Combination of atypical antipsychotic medication in the management of treatment-resistant schizophrenia and schizoaffective disorder
    • Lerner V, Libov I, Kotler M, Strous RD. Combination of "atypical" antipsychotic medication in the management of treatment-resistant schizophrenia and schizoaffective disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2004;28: 89-98.
    • (2004) Prog Neuropsychopharmacol Biol Psychiatry , vol.28 , pp. 89-98
    • Lerner, V.1    Libov, I.2    Kotler, M.3    Strous, R.D.4
  • 37
    • 77954735701 scopus 로고    scopus 로고
    • Publication bias and its implications for evidence-based clinical decision making
    • Crawford JM, Briggs CL, Engeland CG. Publication bias and its implications for evidence-based clinical decision making. J Dent Educ. 2010;74:593-600.
    • (2010) J Dent Educ , vol.74 , pp. 593-600
    • Crawford, J.M.1    Briggs, C.L.2    Engeland, C.G.3
  • 38
    • 31344459099 scopus 로고    scopus 로고
    • Augmentation strategies in clozapine-resistant schizophrenia
    • Remington G, Saha A, Chong S, Shammi C. Augmentation strategies in clozapine-resistant schizophrenia. CNS Drugs. 2005;19:843-872.
    • (2005) CNS Drugs , vol.19 , pp. 843-872
    • Remington, G.1    Saha, A.2    Chong, S.3    Shammi, C.4
  • 39
    • 0002278234 scopus 로고    scopus 로고
    • The expert consensus guideline series: Treatment of schizophrenia
    • Frances A, Docherty JP, Kahn DA. The expert consensus guideline series: treatment of schizophrenia. J Clin Psychiatry. 1996;57:1-50.
    • (1996) J Clin Psychiatry , vol.57 , pp. 1-50
    • Frances, A.1    Docherty, J.P.2    Kahn, D.A.3
  • 41
    • 69449100622 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • PRISMA Group doi: 10.1136/bmj.b2535
    • Moher D, Liberati A, Tetzlaff J, Altman DG. PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339:b2535 doi: 10.1136/bmj.b2535.
    • (2009) BMJ , vol.339
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 44
    • 0023606101 scopus 로고
    • The positive and negative syndrome scale (PANSS) for schizophrenia
    • Kay SR, Fiszbein A, Opler LA. The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13:261-276.
    • (1987) Schizophr Bull , vol.13 , pp. 261-276
    • Kay, S.R.1    Fiszbein, A.2    Opler, L.A.3
  • 45
    • 0000503515 scopus 로고
    • The brief psychiatric rating scale
    • Overall JE, Gorham DR. The brief psychiatric rating scale. Psychol Rep. 1962;10:790-812.
    • (1962) Psychol Rep , vol.10 , pp. 790-812
    • Overall, J.E.1    Gorham, D.R.2
  • 48
    • 0002526947 scopus 로고    scopus 로고
    • Metaanalysis of experiments with matched groups or repeated measures designs
    • Dunlap WP, Cortina JM, Vaslow JB, Burke MJ. Metaanalysis of experiments with matched groups or repeated measures designs. Psychol Methods. 1996;1:170-177.
    • (1996) Psychol Methods , vol.1 , pp. 170-177
    • Dunlap, W.P.1    Cortina, J.M.2    Vaslow, J.B.3    Burke, M.J.4
  • 49
    • 0001424765 scopus 로고
    • Combining estimates of effect size
    • Cooper H Hedges LV eds New York NY: Russell Sage Foundation
    • Shadish WR, Haddock CK. Combining estimates of effect size. In: Cooper H, Hedges LV, eds. The Handbook of Research Synthesis. New York, NY: Russell Sage Foundation; 1994:261-281.
    • (1994) The Handbook of Research Synthesis , pp. 261-281
    • Shadish, W.R.1    Haddock, C.K.2
  • 52
    • 18844441253 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled, crossover trial of clozapine plus glycine in refractory schizophrenia negative results
    • Diaz P, Bhaskara S, Dursun SM, Deakin B. Double-blind, placebo-controlled, crossover trial of clozapine plus glycine in refractory schizophrenia negative results. J Clin Psychopharmacol. 2005;25:277-278.
    • (2005) J Clin Psychopharmacol , vol.25 , pp. 277-278
    • Diaz, P.1    Bhaskara, S.2    Dursun, S.M.3    Deakin, B.4
  • 53
    • 0033557737 scopus 로고    scopus 로고
    • A placebocontrolled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia
    • Goff DC, Henderson DC, Evins AE, Amico E. A placebocontrolled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia. Biol Psychiatry. 1999;45: 512-514.
    • (1999) Biol Psychiatry , vol.45 , pp. 512-514
    • Goff, D.C.1    Henderson, D.C.2    Evins, A.E.3    Amico, E.4
  • 54
    • 33645215658 scopus 로고    scopus 로고
    • Amisulpride treatment of clozapine-induced hypersalivation in schizophrenia patients: A randomized, double-blind, placebo-controlled cross-over study
    • Kreinin A, Novitski D, Weizman A. Amisulpride treatment of clozapine-induced hypersalivation in schizophrenia patients: a randomized, double-blind, placebo-controlled cross-over study. Int Clin Psychopharmacol. 2006;21:99-103.
    • (2006) Int Clin Psychopharmacol , vol.21 , pp. 99-103
    • Kreinin, A.1    Novitski, D.2    Weizman, A.3
  • 55
    • 23944506267 scopus 로고    scopus 로고
    • Topiramate add-on in treatment-resistant schizophrenia: A randomized, doubleblind, placebo-controlled, crossover trial
    • Tiihonen J, Halonen P, Wahlbeck K. Topiramate add-on in treatment-resistant schizophrenia: a randomized, doubleblind, placebo-controlled, crossover trial. J Clin Psychiatry. 2005;66:1012-1015.
    • (2005) J Clin Psychiatry , vol.66 , pp. 1012-1015
    • Tiihonen, J.1    Halonen, P.2    Wahlbeck, K.3
  • 56
    • 34249323746 scopus 로고    scopus 로고
    • The effect of lamotrigine augmentation of clozapine in a sample of treatment-resistant schizophrenic patients: A double-blind, placebo-controlled study
    • Zoccali R, Muscatello MR, Bruno A, et al. The effect of lamotrigine augmentation of clozapine in a sample of treatment-resistant schizophrenic patients: a double-blind, placebo-controlled study. Schizophr Res. 2007;93:109-116.
    • (2007) Schizophr Res , vol.93 , pp. 109-116
    • Zoccali, R.1    Muscatello, M.R.2    Bruno, A.3
  • 57
    • 67649177544 scopus 로고    scopus 로고
    • Topiramate addon treatment in schizophrenia: A randomized, double-blind, placebo-controlled clinical trial
    • Afshar H, Roohafza H, Mousavi G, et al. Topiramate addon treatment in schizophrenia: a randomized, double-blind, placebo-controlled clinical trial. J Psychopharmacol. 2009; 23:157-162.
    • (2009) J Psychopharmacol , vol.23 , pp. 157-162
    • Afshar, H.1    Roohafza, H.2    Mousavi, G.3
  • 58
    • 79955375973 scopus 로고    scopus 로고
    • Topiramate augmentation of clozapine in schizophrenia: A double-blind, placebo-controlled study
    • July 8 doi:10.117/0269881110372548
    • Muscatello MRA, Bruno A, Pandolfo G. Topiramate augmentation of clozapine in schizophrenia: a double-blind, placebo-controlled study. J Psychopharmacol. July 8, 2010; doi:10.117/0269881110372548.
    • (2010) J Psychopharmacol
    • Muscatello, M.R.A.1    Bruno, A.2    Pandolfo, G.3
  • 59
    • 84866689003 scopus 로고    scopus 로고
    • A randomized, placebo-controlled clinical trial of combined citalopram and clozapine in the treatment of negative symptoms of schizophrenia
    • Lan GX, Li ZC, Li L. A randomized, placebo-controlled clinical trial of combined citalopram and clozapine in the treatment of negative symptoms of schizophrenia. Chin Ment Health J. 2006;20:696-698.
    • (2006) Chin Ment Health J , vol.20 , pp. 696-698
    • Lan, G.X.1    Li, Z.C.2    Li, L.3
  • 60
    • 1542286227 scopus 로고    scopus 로고
    • The effect of mirtazapine augmentation of clozapine in the treatment of negative symptoms of schizophrenia: A double-blind, placebo-controlled study
    • Zoccali R, Muscatello MR, Cedro C, et al. The effect of mirtazapine augmentation of clozapine in the treatment of negative symptoms of schizophrenia: a double-blind, placebo-controlled study. Int Clin Psychopharmacol. 2004; 19:71-76.
    • (2004) Int Clin Psychopharmacol , vol.19 , pp. 71-76
    • Zoccali, R.1    Muscatello, M.R.2    Cedro, C.3
  • 61
    • 67649723855 scopus 로고    scopus 로고
    • Mirtazapine add-on therapy in the treatment of schizophrenia with atypical antipsychotics: A double-blind, randomised, placebo-controlled clinical trial
    • Berk M, Gama CS, Sundram S, et al. Mirtazapine add-on therapy in the treatment of schizophrenia with atypical antipsychotics: a double-blind, randomised, placebo-controlled clinical trial. Hum Psychopharmacol. 2009;24:233-238.
    • (2009) Hum Psychopharmacol , vol.24 , pp. 233-238
    • Berk, M.1    Gama, C.S.2    Sundram, S.3
  • 62
    • 4444352847 scopus 로고    scopus 로고
    • Placebo-controlled trial of lamotrigine added to conventional and atypical antipsychotics in schizophrenia
    • Kremer I, Vass A, Gorelik I, et al. Placebo-controlled trial of lamotrigine added to conventional and atypical antipsychotics in schizophrenia. Biol Psychiatry. 2004;56:441-446.
    • (2004) Biol Psychiatry , vol.56 , pp. 441-446
    • Kremer, I.1    Vass, A.2    Gorelik, I.3
  • 63
    • 13844311144 scopus 로고    scopus 로고
    • A double-blind controlled study of adjunctive treatment with risperidone in schizophrenic patients partially responsive to clozapine: Efficacy and safety
    • Anil Yagcioglu AE, Kiviricik Akdede BB, Turgut TI, et al. A Double-Blind Controlled Study of Adjunctive Treatment With Risperidone in Schizophrenic Patients Partially Responsive to Clozapine: efficacy and Safety. J Clin Psychiatry. 2005;66:63-72.
    • (2005) J Clin Psychiatry , vol.66 , pp. 63-72
    • Anil Yagcioglu, A.E.1    Kiviricik Akdede, B.B.2    Turgut, T.I.3
  • 64
    • 11844304940 scopus 로고    scopus 로고
    • A clozapine augmented with risperidone in the treatment of schizophrenia: A Randomized, double-blind, placebo-controlled trial
    • Josiassen RC, Joseph A, Kohegyi E, et al. A Clozapine Augmented With Risperidone in the Treatment of Schizophrenia: a Randomized, Double-Blind, Placebo-Controlled Trial. Am J Psychiatry. 2005;162:130-136.
    • (2005) Am J Psychiatry , vol.162 , pp. 130-136
    • Josiassen, R.C.1    Joseph, A.2    Kohegyi, E.3
  • 65
    • 39649116488 scopus 로고    scopus 로고
    • Lamotrigine as add-on therapy in schizophrenia: Results of 2 placebo-controlled trials
    • Goff DC, Keefe R, Citrome L, et al. Lamotrigine as add-on therapy in schizophrenia: results of 2 placebo-controlled trials. J Clin Psychopharmacol. 2007;27:582-589.
    • (2007) J Clin Psychopharmacol , vol.27 , pp. 582-589
    • Goff, D.C.1    Keefe, R.2    Citrome, L.3
  • 66
    • 45249113944 scopus 로고    scopus 로고
    • Aripiprazole augmentation in clozapine-treated patients with refractory schizophrenia: An 8-week, randomized, double-blind, placebo-controlled trial
    • Chang JS, Ahn YM, Park HJ, et al. Aripiprazole augmentation in clozapine-treated patients with refractory schizophrenia: An 8-week, randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2008;69(5):720-731.
    • (2008) J Clin Psychiatry , vol.69 , Issue.5 , pp. 720-731
    • Chang, J.S.1    Ahn, Y.M.2    Park, H.J.3
  • 67
    • 77957230409 scopus 로고    scopus 로고
    • Effects of adjunctive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: A randomized, double-blind, placebo-controlled trial
    • Fleischhacker WW, Heikkinen ME, Olié JP, et al. Effects of adjunctive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: a randomized, double-blind, placebo-controlled trial. Int J Neuropsychopharmacol. 2010;13(8):1115-1125.
    • (2010) Int J Neuropsychopharmacol , vol.13 , Issue.8 , pp. 1115-1125
    • Fleischhacker, W.W.1    Heikkinen, M.E.2    Olié, J.P.3
  • 68
    • 65749099791 scopus 로고    scopus 로고
    • Haloperidol in combination with clozapine in treatment-refractory patients with schizophrenia
    • Mossaheb N, Sacher J, Wiesegger G, et al. Haloperidol in combination with clozapine in treatment-refractory patients with schizophrenia. Eur Neuropsychopharmacol. 2006; 16(suppl. 4):416.
    • (2006) Eur Neuropsychopharmacol , vol.16 , Issue.SUPPL. 4 , pp. 416
    • Mossaheb, N.1    Sacher, J.2    Wiesegger, G.3
  • 69
    • 78651343292 scopus 로고    scopus 로고
    • Adjunctive risperidone for partially responsive people with schizophrenia treated with clozapine
    • July 21 doi:10. 1038/npp.2010.101
    • Weiner E, Conley RR, Ball MP, et al. July 21, 2010. Adjunctive risperidone for partially responsive people with schizophrenia treated with clozapine. Neuropsychopharmacol. doi:10. 1038/npp.2010.101.
    • (2010) Neuropsychopharmacol
    • Weiner, E.1    Conley, R.R.2    Ball, M.P.3
  • 70
    • 0034796599 scopus 로고    scopus 로고
    • A placebo-controlled pilot study of the ampakine CX516 added to clozapine in schizophrenia
    • Goff DC, Leahy L, Berman I, et al. A placebo-controlled pilot study of the ampakine CX516 added to clozapine in schizophrenia. J Clin Psychopharmacol. 2001;21:484-487.
    • (2001) J Clin Psychopharmacol , vol.21 , pp. 484-487
    • Goff, D.C.1    Leahy, L.2    Berman, I.3
  • 72
    • 0032955821 scopus 로고    scopus 로고
    • Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia
    • Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry. 1999;156: 145-147.
    • (1999) Am J Psychiatry , vol.156 , pp. 145-147
    • Potkin, S.G.1    Jin, Y.2    Bunney, B.G.3    Costa, J.4    Gulasekaram, B.5
  • 73
    • 33748751382 scopus 로고    scopus 로고
    • Glycine transporter i inhibitor N-methylglycine (sarcosine) added to clozapine for the treatment of schizophrenia
    • Lane HY, Huang CL, Wu PL, et al. Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to clozapine for the treatment of schizophrenia. Biol Psychiatry. 2006;60: 645-649.
    • (2006) Biol Psychiatry , vol.60 , pp. 645-649
    • Lane, H.Y.1    Huang, C.L.2    Wu, P.L.3
  • 74
    • 38849155770 scopus 로고    scopus 로고
    • Amisulpride augmentation in patients with schizophrenia partially responsive or unresponsive to clozapine. A randomized, double-blind, placebo-controlled trial
    • Assion HJ, Reinbold H, Lemanski S, Basilowski M, Juckel G. Amisulpride augmentation in patients with schizophrenia partially responsive or unresponsive to clozapine. A randomized, double-blind, placebo-controlled trial. Pharmacopsychiatry. 2008;41:24-28.
    • (2008) Pharmacopsychiatry , vol.41 , pp. 24-28
    • Assion, H.J.1    Reinbold, H.2    Lemanski, S.3    Basilowski, M.4    Juckel, G.5
  • 76
    • 65749098355 scopus 로고    scopus 로고
    • Augmentation of clozapine with a second antipsychotic - A meta-analysis of randomized, placebo-controlled studies
    • Taylor DM, Smith L. Augmentation of clozapine with a second antipsychotic-a meta-analysis of randomized, placebo-controlled studies. Acta Psychiatr Scand. 2009;119: 419-425.
    • (2009) Acta Psychiatr Scand , vol.119 , pp. 419-425
    • Taylor, D.M.1    Smith, L.2
  • 77
    • 65349163482 scopus 로고    scopus 로고
    • Does the addition of a second antipsychotic drug improve clozapine treatment?
    • Barbui C, Signoretti A, Mulè S, Boso M, Cipriani A. Does the addition of a second antipsychotic drug improve clozapine treatment? Schizophr Bull. 2009;35:458-468.
    • (2009) Schizophr Bull , vol.35 , pp. 458-468
    • Barbui, C.1    Signoretti, A.2    Mulè, S.3    Boso, M.4    Cipriani, A.5
  • 79
    • 62649086513 scopus 로고    scopus 로고
    • The efficacy of lamotrigine in clozapine-resistant schizophrenia: A systematic review and meta-analysis
    • Tiihonen J, Wahlbeck K, Kiviniemi V. The efficacy of lamotrigine in clozapine-resistant schizophrenia: a systematic review and meta-analysis. Schizophr Res. 2009;109: 10-14.
    • (2009) Schizophr Res , vol.109 , pp. 10-14
    • Tiihonen, J.1    Wahlbeck, K.2    Kiviniemi, V.3
  • 80
    • 9644279552 scopus 로고    scopus 로고
    • Effect sizes in cumulative meta-analyses of mental health randomized trials evolved over time
    • EU-PSI project
    • Trikalinos TA, Churchill R, Ferri M, et al. EU-PSI project. Effect sizes in cumulative meta-analyses of mental health randomized trials evolved over time. J Clin Epidemiol. 2004; 57:1124-1130.
    • (2004) J Clin Epidemiol , vol.57 , pp. 1124-1130
    • Trikalinos, T.A.1    Churchill, R.2    Ferri, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.