Haptoglobin alters oxygenation and oxidation of hemoglobin and decreases propagation of peroxide-induced oxidative reactions

Free Radical Biology and Medicine

Volumn 53, Issue 6, 2012, Pages 1317-1326

  Banerjee, Sambuddha ^a   Jia, Yiping ^b   Parker Siburt, Claire J ^a   Abraham, Bindu ^b   Wood, Francine ^b   Bonaventura, Celia ^c   Henkens, Robert ^c   Crumbliss, Alvin L ^a   Alayash, Abdu I ^b  

^a DUKE UNIVERSITY   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^c DUKE UNIVERSITY MARINE LABORATORY   (United States)

Author keywords

Ferryl hemoglobin; Haptoglobin; Hemoglobin; Oxygen; Peroxidase; Redox potential

Indexed keywords

CARBON MONOXIDE; HAPTOGLOBIN; HEME; HEMOGLOBIN; HYDROGEN PEROXIDE; OXYGEN; PHOSPHATE;

ANAEROBIC METABOLISM; ARTICLE; BINDING AFFINITY; CHEMICAL REACTION KINETICS; COMPLEX FORMATION; CONTROLLED STUDY; DEOXYGENATION; DIMERIZATION; DISSOCIATION; ELECTROCHEMISTRY; ENZYME ACTIVE SITE; LIGAND BINDING; OXIDATION REDUCTION POTENTIAL; OXYGENATION; PH; PRIORITY JOURNAL;

CARBON MONOXIDE; CYCLIC N-OXIDES; FREE RADICAL SCAVENGERS; HAPTOGLOBINS; HEMOGLOBINS; HUMANS; HYDROGEN PEROXIDE; HYDROGEN-ION CONCENTRATION; KINETICS; OXIDANTS; OXIDATION-REDUCTION; OXYGEN; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN SUBUNITS;

EID: 84865325486     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.07.023     Document Type: Article

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