The DJ-1 concentration in cerebrospinal fluid does not differentiate among Parkinsonian syndromes

Parkinsonism and Related Disorders

Volumn 18, Issue 7, 2012, Pages 899-901

  Salvesen, Lisette ^a   Bech, Sara ^a,b   Lokkegaard, Annemette ^a   Hjermind, Lena E ^a,b,c   Nielsen, Jorgen E ^b,c   Pakkenberg, Bente ^a   Tanassi, Julia T ^d   Heegaard, Niels H H ^d   Winge, Kristian ^a  

^a BISPEBJERG HOSPITAL   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c Rigshospitalet   (Denmark)

^d STATENS SERUM INSTITUT   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; DJ 1 PROTEIN;

ADULT; AGED; DIAGNOSTIC VALUE; DIFFUSE LEWY BODY DISEASE; FEMALE; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; PARKINSONISM; PRIORITY JOURNAL; PROGRESSIVE SUPRANUCLEAR PALSY; PROTEIN CEREBROSPINAL FLUID LEVEL; SHY DRAGER SYNDROME;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; FEMALE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; ONCOGENE PROTEINS; PARKINSONIAN DISORDERS;

EID: 84865324419     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2012.03.013     Document Type: Letter

References (5)

1. Bonifati V., Rizzu P., van Baren M.J., Schaap O., Breedveld G.J., Krieger E., et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003, 299:256-259.
2. Batelli S., Albani D., Rametta R., Polito L., Prato F., Pesaresi M., et al. DJ-1 modulates α-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70. PLoS ONE 2008, 3(4):e1884. 10.1371/journal.pone.0001884.
3. Shi M., Bradner J., Hancock A.M., Chung K.A., Quinn J., Peskind E.R., et al. Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression. Ann Neurol 2011, 69:570-580.
4. Hong Z., Shi M., Chung K.A., Quinn J.F., Peskind E.R., Galasko D., et al. DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain 2010, 133:713-726.
5. Teunissen C.E., Petzold A., Bennett J.L., Berven F.S., Brundin L., Comabella M., et al. A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking. Neurology 2009, 73:1914-1922.