Manipulating antioxidant intake in asthma: A randomized controlled trial1-3

American Journal of Clinical Nutrition

Volumn 96, Issue 3, 2012, Pages 534-543

  Wood, Lisa G ^a,c   Garg, Manohar L ^b   Smart, Joanne M ^a   Scott, Hayley A ^a   Barker, Daniel ^c   Gibson, Peter G ^a,c  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c JOHN HUNTER HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; C REACTIVE PROTEIN; CAROTENOID; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; INTERLEUKIN 6; INTERLEUKIN 8; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LYCOPENE; THEOPHYLLINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; ASTHMA; ATOPY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIET; DIETARY INTAKE; DISEASE EXACERBATION; FEMALE; FORCED EXPIRATORY VOLUME; FRUIT; HIGH ANTIOXIDANT DIET; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LOW ANTIOXIDANT DIET; MAJOR CLINICAL STUDY; MALE; NUTRITIONAL ASSESSMENT; OUTCOME ASSESSMENT; PLACEBO EFFECT; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL; SMOKING; SPIROMETRY; SPUTUM EXAMINATION; TOMATO; VEGETABLE;

ADULT; AGED; ANTIOXIDANTS; ASTHMA; C-REACTIVE PROTEIN; CAROTENOIDS; DIET; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; FRUIT; HUMANS; INFLAMMATION MEDIATORS; LYCOPERSICON ESCULENTUM; MALE; MIDDLE AGED; OXIDATIVE STRESS; PATIENT DROPOUTS; PLANT EXTRACTS; RESPIRATORY SYSTEM; VEGETABLES;

EID: 84865322444     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.111.032623     Document Type: Article

References (56)

1. Wood LG, Gibson PG, Garg ML. Biomarkers of lipid peroxidation, airway inflammation and asthma. Eur Respir J 2003;21:177-86.
2. Rhoden KJ, Barnes PJ. Effect of hydrogen peroxide on guinea-pig tracheal muscle in vitro: role of cyclo-oxygenase and airway epithelium. Br J Pharmacol 1989;98:325-30.
3. Adler KB, Holden-Stauffer WJ, Repine JE. Oxygen metabolites stimulate release of high-molecular weight glycoconjugates by cell and organ cultures of rodent respiratory epithelium via arachidonic acid dependent mechanism. J Clin Invest 1990;85:75-85.
4. Doelman CJA, Leurs R, Oosterom WC, Bast A. Mineral dust exposure and free radical-mediated lung damage. Exp Lung Res 1990;16:41-55.
5. Tate RM, van Benthuysen KM, Shasby DM, McMurtry IF, Repine JE. Oxygen-radical-mediated permability edema and vasoconstriction in isolated perfused rabbit lungs. Am Rev Respir Dis 1982;126:802-6.
6. Katsumata U, Miura M, Ichinose M, Kimura K, Takahashi T, Inoue H, Takishima T. Oxygen radicals produce airway constriction and hyperresponsiveness in anesthetized cats. Am Rev Respir Dis 1990;141: 1158-61.
7. Butland BK, Strachan DP, Anderson HR. Fresh fruit intake and asthma symptoms in young British adults: confounding or effect modification by smoking? Eur Respir J 1999;13:744-50.
8. Miedema I, Feskens EJM, Heederik D, Kromhout D. Dietary determinants of long-term incidence of chronic non-specific lung diseases: the Zutphen study. Am J Epidemiol 1993;138:37-45.
9. Cook DG, Carey IM, Whincup PH. Effect of fresh fruit consumption on lung function and wheeze in children. Thorax 1997;52:628-33.
10. Carey IM, Strachan D, Cook D. Effects of changes in fresh fruit consumption on ventilatory function in healthy British adults. Am J Respir Crit Care Med 1998;158:728-33.
11. Shaheen SO, Sterne JAC, Thompson RL, Songhurst CE, Margetts BM, Burney PGJ. Dietary antioxidants and asthma in adults. Am J Respir Crit Care Med 2001;164:1823-8.
12. Dow L, Tracey M, Villar A. Does dietary intake of vitamin C and E influence lung function in older people? Am J Respir Crit Care Med 1996;154:1401-4.
13. Morabia A, Sorenson A, Kumanyika SK, Abbey H, Cohen BH, Chee E. Vitamin A, cigarette smoking, and airway obstruction. Am Rev Respir Dis 1989;140:1312-6.
14. Troisi RJ, Willett WC, Weiss ST, Trichopoulis D, Rosner B, Speizer FE. A prospective study of diet and adult-onset asthma. Am J Respir Crit Care Med 1995;151:1401-8.
15. La Vecchia C, Decarli A, Pagano R. Vegetable consumption and risk of chronic disease. Epidemiology 1998;9:208-10.
16. Ellwood P, Asher MI, Bjorksten B, Burr M, Pearce N, Robertson CF, Group IPOS. Diet and asthma, allergic rhinoconjunctivitis and atopic eczema symptom prevalence: an ecological analysis of the International Study of Asthma and Allergies in Childhood (ISAAC) data. Eur Respir J 2001;17:436-43.
17. Wood LG, Garg ML, Blake RJ, Garcia-Caraballo S, Gibson PG. Airway and circulating levels of carotenoids in asthma and healthy controls. J Am Coll Nutr 2005;24:448-55.
18. Hazlewood LC, Wood LG, Hansbro PM, Foster PS. Dietary lycopene supplementation suppresses Th2 responses and lung eosinophilia in a mouse model of allergic asthma. J Nutr Biochem 2011;22:95-100.
19. Saedisomeolia A, Wood LG, Garg ML, Gibson PG, Wark PA. Lycopene enrichment of cultured airway epithelial cells decreases the inflammation induced by rhinovirus infection and lipopolysaccharide. J Nutr Biochem 2009;20:577-85.
20. Wood LG, Garg ML, Powell H, Gibson PG. Lycopene-rich treatments modify noneosinophilic airway inflammation in asthma: proof of concept. Free Radic Res 2008;42:94-102.
21. Neuman I, Nahum H. Reduction of exercise-induced asthma oxidative stress by lycopene, a natural antioxidant. Allergy 2000;55:1184-9.
22. National Institutes of Health. Global strategy for asthma management and prevention revised: workshop report. Global Initiative for Asthma. Bethesda, MD: 2002.
23. Juniper EF, O'Byrne PM, Guyatt GH, Ferrie PJ, King DR. Development and validation of a questionnaire to measure asthma control. Eur Respir J 1999;14:902-7.
24. Gibson PG, Wlodarczyk J, Hensley M, Gleeson M, Henry RL, Cripps AW, Clancy RL. Epidemiological association of airway inflammation with asthma symptoms and airway hyperresponsiveness in childhood. Am J Respir Crit Care Med 1998;158:36-41.
25. Simpson JL, Scott RJ, Boyle MJ, Gibson PG. Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma. Am J Respir Crit Care Med 2005;172:559-65.
26. Wood LG, Garg ML, Simpson JL, Mori TA, Croft KD, Wark PAB, Gibson PG. Induced sputum 8-isoprostane concentrations in inflammatory airway diseases. Am J Respir Crit Care Med 2005;171:426-30.
27. Barua AB, Kostic D, Olson JA. New simplified procedures for the extraction and simultaneous high-performance liquid chromatographic analysis of retinol, tocopherols, and carotenoids in human serum. J Chromatogr 1993;617:257-64.
28. Devereux G, Seaton A. Diet as a risk factor for atopy and asthma. J Allergy Clin Immunol 2005;115:1109-17.
29. McKeever TM, Britton J. Diet and asthma. Am J Respir Crit Care Med 2004;170:725-9.
30. Fogarty AW, Antoniak M, Venn AJ, Davies L, Goodwin A, Salfield N, Britton JR, Lewis SA. A natural experiment on the impact of fruit supplementation on asthma symptoms in children. Eur Respir J 2009; 33:481-5.
31. Keranis E, Makris D, Rodopoulou P, Martinou H, Papamakarios G, Daniil Z, Zintzaras E, Gourgoulianis KI. Impact of dietary shift to higher-antioxidant foods in COPD: a randomised trial. Eur Respir J 2010;36:774-80.
32. Watzl B, Kulling SE, Moseneder J, Barth SW, Bub A. A 4-wk intervention with high intake of carotenoid-rich vegetables and fruit reduces plasma C-reactive protein in healthy, nonsmoking men. Am J Clin Nutr 2005;82:1052-8.
33. Esposito K, Marfella R, Ciotola M, Di Palo C, Giugliano F, Giugliano G, D'Armiento M, D'Andrea F, Giugliano D. Effect of Mediterranean- Style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome. JAMA 2004;292:1440-6.
34. Gao X, Bermudez OI, Tucker KL. Plasma C-reactive protein and homocysteine concentrations are related to frequent fruit and vegetable intake in Hispanic and non-Hispanic white elders. J Nutr 2004;134: 913-8.
35. Wannamethee SG, Lowe GD, Rumley A, Bruckdorfer KR, Whincup PH. Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis. Am J Clin Nutr 2006;83:567-74, quiz 726-7.
36. Esmaillzadeh A, Kimiagar M, Mehrabi Y, Azadbakht L, Hu FB,Willett WC. Fruit and vegetable intakes, C-reactive protein, and the metabolic syndrome. Am J Clin Nutr 2006;84:1489-97.
37. Wood LG, Baines KJ, Fu J, Scott HA, Gibson PG. The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma. Chest (Epub ahead of print 16 February 2012).
38. Olafsdottir IS, Gislason T, Thjodleifsson B, Olafsson I, Gislason D, Jogi R, Janson C. C reactive protein levels are increased in non-allergic but not allergic asthma: a multicentre epidemiological study. Thorax 2005;60:451-4.
39. Takemura M, Matsumoto H, Niimi A, Ueda T, Matsuoka H, Yamaguchi M, Jinnai M, Muro S, Hirai T, Ito Y, et al. High sensitivity C-reactive protein in asthma. Eur Respir J 2006;27:908-12.
40. SchmitzML, Baeuerle PA. The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B. EMBO J 1991;10: 3805-17.
41. Kim GY, Kim JH, Ahn SC, Lee HJ, Moon DO, Lee CM, Park YM. Lycopene suppresses the lipopolysaccharide-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and nuclear factor-kappaB. Immunology 2004;113:203-11.
42. Wang XD. Review: absorption and metabolism of beta-carotene. J Am Coll Nutr 1994;13:314-25.
43. Karas M, Amir H, Fishman D, Danilenko M, Segal S, Nahum A, Koifmann A, Giat Y, Levy J, Sharoni Y. Lycopene interferes with cell cycle progression and insulin-like growth factor I signaling in mammary cancer cells. Nutr Cancer 2000;36:101-11.
44. Martin KR, Wu D, Meydani M. The effect of carotenoids on the expression of cell surface adhesion molecules and binding of monocytes to human aortic endothelial cells. Atherosclerosis 2000;150:265-74.
45. Ben-Dor A, Steiner M, Gheber L, Danilenko M, Dubi N, Linnewiel K, Zick A, Sharoni Y, Levy J. Carotenoids activate the antioxidant response element transcription system. Mol Cancer Ther 2005;4:177-86.
46. Australian Government Department for Health and Aging. National Health and Medical Research Council. Dietary guidelines for Australians: a guide to healthy eating. Available from: http://www.nhmrc.gov.au/-files-nhmrc/file/ publications/synopses/n31.pdf (cited January 2011).
47. US Department of Health and Human Services. US Department of Agriculture. Dietary guidelines for Americans 2005. Available from: www.healthierus.gov/ dietaryguidelines (cited January 2011).
48. NSW Department of Health Epidemiology and Surveillance Branch. NSW Health Surveys 1997 and 1998 (HOIST). 2001. Available from: www.health.nsw.gov.au (cited April 2006).
49. AnahCO. High dose ascorbic acid in nigerian asthmatics. Trop Geogr Med 1980;32:132-7.
50. Schachter EN, Schlesinger A. The attenuation of exercise-induced bronchospasm by ascorbic acid. Ann Allergy 1982;49:146-51.
51. Mohsenin V, Dubois AB, Douglas JS. Effect of ascorbic acid on response to methacholine challenge in asthmatic subjects. Am Rev Respir Dis 1983;127:143-7.
52. Zuskin E, Lewis AJ, Bouhuys A. Inhibition of histamine-induced airway constriction by ascorbic acid. J Allergy Clin Immunol 1973;51:218-26.
53. Malo JL, Cartier A, Pineau L, L'Archeveque J, Ghezzo H, Martin RR. Lack of acute effects of ascorbic acid on spirometry and airway responsiveness to histamine in subjects with asthma. J Allergy Clin Immunol 1986;78:1153-8.
54. Ting S, Mansfield LE, Yarbrough J. Effects of ascorbic acid on pulmonary functions in mild asthma. J Asthma 1983;20:39-42.
55. Hasselmark L, Malmgren R, Zetterstrom O, Unge G. Selenium supplementation in intrinsic asthma. Allergy 1993;48:30-6.
56. Pearson PJ, Lewis SA, Britton J, Fogarty A. Vitamin E supplements in asthma: a parallel group randomised placebo controlled trial. Thorax 2004;59:652-6.