-
1
-
-
81855199724
-
The role of environmental exposures in neurodegeneration and neurodegenerative diseases
-
Cannon JR, Greenamyre JT. The role of environmental exposures in neurodegeneration and neurodegenerative diseases. Toxicol Sci 2011;124:225-50
-
(2011)
Toxicol Sci
, vol.124
, pp. 225-250
-
-
Cannon, J.R.1
Greenamyre, J.T.2
-
2
-
-
60849093466
-
Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
-
Rothstein JD. Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann Neurol 2009;65(Suppl. 1):S3-9.
-
(2009)
Ann Neurol
, vol.65
, Issue.1 SUPPL.
-
-
Rothstein, J.D.1
-
5
-
-
0015504203
-
The pathogenesis of amyotrophic lateral sclerosis
-
Yase Y. The pathogenesis of amyotrophic lateral sclerosis. Lancet 1972;2:292-6
-
(1972)
Lancet
, vol.2
, pp. 292-296
-
-
Yase, Y.1
-
6
-
-
0030781471
-
Astrocyte metallothioneins (MTs) and their neuroprotective role
-
Aschner M. Astrocyte metallothioneins (MTs) and their neuroprotective role. Ann N Y Acad Sci 1997;825:334-47
-
(1997)
Ann N Y Acad Sci
, vol.825
, pp. 334-347
-
-
Aschner, M.1
-
7
-
-
36849027112
-
Manganese: Pharmacokinetics and molecular mechanisms of brain uptake
-
Aschner M, Dorman DC. Manganese: pharmacokinetics and molecular mechanisms of brain uptake. Toxicol Rev 2006;25:147-54
-
(2006)
Toxicol Rev
, vol.25
, pp. 147-154
-
-
Aschner, M.1
Dorman, D.C.2
-
8
-
-
0141560468
-
Brain barrier systems: A new frontier in metal neurotoxicological research
-
Zheng W, Aschner M, Ghersi-Egea JF. Brain barrier systems: a new frontier in metal neurotoxicological research. Toxicol Appl Pharmacol 2003;192:1-11
-
(2003)
Toxicol Appl Pharmacol
, vol.192
, pp. 1-11
-
-
Zheng, W.1
Aschner, M.2
Ghersi-Egea, J.F.3
-
10
-
-
0031569806
-
Essential trace element alterations in amyotrophic lateral sclerosis
-
Kapaki E, Zournas C, Kanias G, Zambelis T, Kakami A, Papageorgiou C. Essential trace element alterations in amyotrophic lateral sclerosis. J Neurol Sci 1997;147:171-5
-
(1997)
J Neurol Sci
, vol.147
, pp. 171-175
-
-
Kapaki, E.1
Zournas, C.2
Kanias, G.3
Zambelis, T.4
Kakami, A.5
Papageorgiou, C.6
-
11
-
-
78149414203
-
Review on metal speciation analysis in cerebrospinal fluid-current methods and results: A review
-
Michalke B, Nischwitz V. Review on metal speciation analysis in cerebrospinal fluid-current methods and results: a review. Anal Chim Acta 2010;682:23 36
-
(2010)
Anal Chim Acta
, vol.23
, Issue.36
, pp. 682
-
-
Michalke, B.1
Nischwitz, V.2
-
12
-
-
52049086213
-
Speciation analysis of selected metals and determination of their total contents in paired serum and cerebrospinal fluid samples: An approach to investigate the permeability of the human blood-cerebrospinal fluid-barrier
-
Nischwitz V, Berthele A, Michalke B. Speciation analysis of selected metals and determination of their total contents in paired serum and cerebrospinal fluid samples: an approach to investigate the permeability of the human blood-cerebrospinal fluid-barrier. Anal Chim Acta 2008;627:258-69
-
(2008)
Anal Chim Acta
, vol.258
, Issue.69
, pp. 627
-
-
Nischwitz, V.1
Berthele, A.2
Michalke, B.3
-
13
-
-
0032716522
-
Consensus guidelines for the design and implementation of clinical trials in ALS. World Federation of Neurology committee on Research
-
Miller RG, Munsat TL, Swash M, Brooks BR. Consensus guidelines for the design and implementation of clinical trials in ALS. World Federation of Neurology committee on Research. J Neurol Sci 1999;169:2-12
-
(1999)
J Neurol Sci
, vol.169
, pp. 2-12
-
-
Miller, R.G.1
Munsat, T.L.2
Swash, M.3
Brooks, B.R.4
-
15
-
-
34548852198
-
Separation of proteins including metallothionein in cerebrospinal fluid by size exclusion HPLC and determination of trace elements by HR-ICP-MS
-
Gellein K, Roos PM, Evje L, Vesterberg O, Flaten TP, Nordberg M, Syversen T. Separation of proteins including metallothionein in cerebrospinal fluid by size exclusion HPLC and determination of trace elements by HR-ICP-MS. Brain Res 2007;1174:136-42
-
(2007)
Brain Res
, vol.1174
, pp. 136-142
-
-
Gellein, K.1
Roos, P.M.2
Evje, L.3
Vesterberg, O.4
Flaten, T.P.5
Nordberg, M.6
Syversen, T.7
-
16
-
-
13944258588
-
Determination of low-abundance elements at ultra-trace levels in urine and serum by inductively coupled plasma-sector field mass spectrometry
-
Rodushkin I, Engstrom E, Stenberg A, Baxter DC. Determination of low-abundance elements at ultra-trace levels in urine and serum by inductively coupled plasma-sector field mass spectrometry. Anal Bioanal Chem 2004;380:247-57
-
(2004)
Anal Bioanal Chem
, vol.380
, pp. 247-257
-
-
Rodushkin, I.1
Engstrom, E.2
Stenberg, A.3
Baxter, D.C.4
-
18
-
-
84865334905
-
Manganese
-
Nordberg GF, Fowler BA, Nordberg M, Friberg LT, eds., 3rd edn. Amsterdam: Elsevier Academic Press
-
Šaric M, Lucchini R. Manganese. In: Nordberg GF, Fowler BA, Nordberg M, Friberg LT, eds. Handbook on the Toxicology of Metals. 3rd edn. Amsterdam: Elsevier Academic Press 2007
-
(2007)
Handbook On the Toxicology of Metals
-
-
Šaric, M.1
Lucchini, R.2
-
19
-
-
34248373301
-
Putative proteins involved in manganese transport across the blood brain barrier
-
Fitsanakis VA, Piccola G, Marreilha dos Santos AP, Aschner JL, Aschner M. Putative proteins involved in manganese transport across the blood brain barrier. Hum Exp Toxicol 2007;26:295-302
-
(2007)
Hum Exp Toxicol
, vol.26
, pp. 295-302
-
-
Fitsanakis, V.A.1
Piccola, G.2
Marreilha dos Santos, A.P.3
Aschner, J.L.4
Aschner, M.5
-
20
-
-
44649152946
-
Metallothionein in the central nervous system: Roles in protection, regeneration and cognition
-
West AK, Hidalgo J, Eddins D, Levin ED, Aschner M. Metallothionein in the central nervous system: roles in protection, regeneration and cognition. Neurotoxicology 2008;29:489-503
-
(2008)
Neurotoxicology
, vol.29
, pp. 489-503
-
-
West, A.K.1
Hidalgo, J.2
Eddins, D.3
Levin, E.D.4
Aschner, M.5
-
21
-
-
0000571322
-
State of binding of natural manganese in human cerebrospinal fluid, blood and plasma
-
Cotzias GC, Papavasiliou PS. State of binding of natural manganese in human cerebrospinal fluid, blood and plasma. Nature 1962;195:823-4
-
(1962)
Nature
, vol.195
, pp. 823-824
-
-
Cotzias, G.C.1
Papavasiliou, P.S.2
-
22
-
-
14444272313
-
Cerebrospinal fluid levels of transition metals in patients with Parkinson's disease
-
Jimenez-Jimenez FJ, Molina JA, Aguilar MV, Meseguer I, Mateos-Vega CJ, Gonzalez-Munoz MJ, de Bustos F, Martínez-Salio A, Ortí-Pareja M, Zurdo M, Martínez-Para MC. Cerebrospinal fluid levels of transition metals in patients with Parkinson's disease. J Neural Transm 1998;105:497-505
-
(1998)
J Neural Transm
, vol.105
, pp. 497-505
-
-
Jimenez-Jimenez, F.J.1
Molina, J.A.2
Aguilar, M.V.3
Meseguer, I.4
Mateos-Vega, C.J.5
Gonzalez-Munoz, M.J.6
de Bustos, F.7
Martínez-Salio, A.8
Ortí-Pareja, M.9
Zurdo, M.10
Martínez-Para, M.C.11
-
23
-
-
34347399955
-
Speciation and toxicological relevance of manganese in humans
-
Michalke B, Halbach S, Nischwitz V. Speciation and toxicological relevance of manganese in humans. J Environ Monit 2007;9:650-6.
-
(2007)
J Environ Monit
, vol.9
, pp. 650-656
-
-
Michalke, B.1
Halbach, S.2
Nischwitz, V.3
-
24
-
-
38849090668
-
Trace elements in cerebrospinal fluid and blood from patients with a rare progressive central and peripheral demyelinating disease
-
Gellein K, Skogholt JH, Aaseth J, Thoresen GB, Lierhagen S, Steinnes E, Syversen T, Flaten TP. Trace elements in cerebrospinal fluid and blood from patients with a rare progressive central and peripheral demyelinating disease. J Neurol Sci 2008;266:70-8.
-
(2008)
J Neurol Sci
, vol.266
, pp. 70-78
-
-
Gellein, K.1
Skogholt, J.H.2
Aaseth, J.3
Thoresen, G.B.4
Lierhagen, S.5
Steinnes, E.6
Syversen, T.7
Flaten, T.P.8
-
25
-
-
0042668325
-
Manganese, copper, and zinc in cerebrospinal fluid from patients with multiple sclerosis
-
Melo TM, Larsen C, White LR, Aasly J, Sjobakk TE, Flaten TP, Sonnewald U, Syversen T. Manganese, copper, and zinc in cerebrospinal fluid from patients with multiple sclerosis. Biol Trace Elem Res 2003;93:1-8
-
(2003)
Biol Trace Elem Res
, vol.93
, pp. 1-8
-
-
Melo, T.M.1
Larsen, C.2
White, L.R.3
Aasly, J.4
Sjobakk, T.E.5
Flaten, T.P.6
Sonnewald, U.7
Syversen, T.8
-
26
-
-
58549098084
-
Blood-brain barrier: Ageing and microvascular disease systematic review and meta-analysis
-
Farrall AJ, Wardlaw JM. Blood-brain barrier: ageing and microvascular disease systematic review and meta-analysis. Neurobiol Aging 2009;30:337-52.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 337-352
-
-
Farrall, A.J.1
Wardlaw, J.M.2
-
27
-
-
43049169876
-
Cerebrospinal fluid to brain transport of manganese in a non-human primate revealed by MRI
-
Bock NA, Paiva FF, Nascimento GC, Newman JD, Silva AC. Cerebrospinal fluid to brain transport of manganese in a non-human primate revealed by MRI. Brain Res 2008;1198:160-70.
-
(2008)
Brain Res
, vol.1198
, pp. 160-170
-
-
Bock, N.A.1
Paiva, F.F.2
Nascimento, G.C.3
Newman, J.D.4
Silva, A.C.5
-
28
-
-
44649108282
-
Duration of airborne-manganese exposure in rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity
-
Erikson KM, Dorman DC, Lash LH, Aschner M. Duration of airborne-manganese exposure in rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity. Neurotoxicology 2008;29:377-85
-
(2008)
Neurotoxicology
, vol.29
, pp. 377-385
-
-
Erikson, K.M.1
Dorman, D.C.2
Lash, L.H.3
Aschner, M.4
-
31
-
-
0028138473
-
Metallothionein in amyotrophic lateral sclerosis
-
Sillevis Smitt PA, Mulder TP, Verspaget HW, Blaauwgeers HG, Troost D, de Jong JM. Metallothionein in amyotrophic lateral sclerosis. Biol Signals 1994;3:193-7
-
(1994)
Biol Signals
, vol.3
, pp. 193-197
-
-
Sillevis, S.P.A.1
Mulder, T.P.2
Verspaget, H.W.3
Blaauwgeers, H.G.4
Troost, D.5
de Jong, J.M.6
-
32
-
-
0026653750
-
Increased metallothionein in the liver and kidney of patients with amyotrophic lateral sclerosis
-
Sillevis Smitt PA, van Beek H, Baars AJ, Troost D, Louwerse ES, Krops-Hermus AC, de Wolff FA, de Jong JM. Increased metallothionein in the liver and kidney of patients with amyotrophic lateral sclerosis. Arch Neurol 1992;49:721-4
-
(1992)
Arch Neurol
, vol.49
, pp. 721-724
-
-
Sillevis, S.P.A.1
van Beek, H.2
Baars, A.J.3
Troost, D.4
Louwerse, E.S.5
Krops-Hermus, A.C.6
de Wolff, F.A.7
de Jong, J.M.8
-
33
-
-
64049116675
-
Manganese neurotoxicity: Lessons learned from longitudinal studies in nonhuman primates
-
Burton NC, Guilarte TR. Manganese neurotoxicity: lessons learned from longitudinal studies in nonhuman primates. Environ Health Perspect 2009;117:325-32
-
(2009)
Environ Health Perspect
, vol.117
, pp. 325-332
-
-
Burton, N.C.1
Guilarte, T.R.2
-
34
-
-
2642541755
-
Manganese toxicokinetics at the blood-brain barrier
-
discussion 9-73
-
Yokel RA, Crossgrove JS. Manganese toxicokinetics at the blood-brain barrier. Res Rep Health Eff Inst 2004;119:7-58; discussion 9-73.
-
(2004)
Res Rep Health Eff Inst
, vol.119
, pp. 7-58
-
-
Yokel, R.A.1
Crossgrove, J.S.2
-
35
-
-
45049088251
-
Intracellular localization and subsequent redistribution of metal transporters in a rat choroid plexus model following exposure to manganese or iron
-
Wang X, Miller DS, Zheng W. Intracellular localization and subsequent redistribution of metal transporters in a rat choroid plexus model following exposure to manganese or iron. Toxicol Appl Pharmacol 2008;230:167-74
-
(2008)
Toxicol Appl Pharmacol
, vol.230
, pp. 167-174
-
-
Wang, X.1
Miller, D.S.2
Zheng, W.3
-
36
-
-
33845266489
-
Changes in blood manganese concentration and MRI t1 relaxation time during 180 days of stainless steel welding-fume exposure in cynomolgus monkeys
-
Sung JH, Kim CY, Yang SO, Khang HS, Cheong HK, Lee JS, Song CW Park JD, Han JH, Chung YH, Choi BS, Kwon IH, Cho MH, Yu IJ. Changes in blood manganese concentration and MRI t1 relaxation time during 180 days of stainless steel welding-fume exposure in cynomolgus monkeys. Inhal Toxicol 2007;19:47-55
-
(2007)
Inhal Toxicol
, vol.19
, pp. 47-55
-
-
Sung, J.H.1
Kim, C.Y.2
Yang, S.O.3
Khang, H.S.4
Cheong, H.K.5
Lee, J.S.6
Song, C.W.7
Park, J.D.8
Han, J.H.9
Chung, Y.H.10
Choi, B.S.11
Kwon, I.H.12
Cho, M.H.13
Yu, I.J.14
-
37
-
-
0345283186
-
Whole blood manganese correlates with high signal intensities on T1-weighted MRI in patients with liver cirrhosis
-
Park NH, Park JK, Choi Y, Yoo CI, Lee CR, Lee H, Kim HK, Kim SR, Jeong TH, Park J, Yoon CS, Kim Y. Whole blood manganese correlates with high signal intensities on T1-weighted MRI in patients with liver cirrhosis. Neurotoxicology 2003;24:909-15
-
(2003)
Neurotoxicology
, vol.24
, pp. 909-915
-
-
Park, N.H.1
Park, J.K.2
Choi, Y.3
Yoo, C.I.4
Lee, C.R.5
Lee, H.6
Kim, H.K.7
Kim, S.R.8
Jeong, T.H.9
Park, J.10
Yoon, C.S.11
Kim, Y.12
-
38
-
-
0023432785
-
Hepatic ultrastructural change and liver dysfunction in amyotrophic lateral sclerosis
-
Fisman M. Hepatic ultrastructural change and liver dysfunction in amyotrophic lateral sclerosis. Arch Neurol 1987;44-997
-
(1987)
Arch Neurol
, pp. 44-997
-
-
Fisman, M.1
-
39
-
-
0021816196
-
Functional and morphometric study of the liver in motor neuron disease
-
Masui Y, Mozai T, Kakehi K. Functional and morphometric study of the liver in motor neuron disease. J Neurol 1985;232:15-9
-
(1985)
J Neurol
, vol.232
, pp. 15-19
-
-
Masui, Y.1
Mozai, T.2
Kakehi, K.3
-
40
-
-
0023270442
-
Hepatic ultrastructural changes and liver dysfunction in amyotrophic lateral sclerosis
-
Nakano Y, Hirayama K, Terao K. Hepatic ultrastructural changes and liver dysfunction in amyotrophic lateral sclerosis. Arch Neurol 1987;44:103-6
-
(1987)
Arch Neurol
, vol.44
, pp. 103-106
-
-
Nakano, Y.1
Hirayama, K.2
Terao, K.3
-
41
-
-
0020523160
-
Increased manganese level in spinal cords of amyotrophic lateral sclerosis determined by radiochemical neutron activation analysis
-
Miyata S, Nakamura S, Nagata H, Kameyama M. Increased manganese level in spinal cords of amyotrophic lateral sclerosis determined by radiochemical neutron activation analysis. J Neurol Sci 1983;61:283-93
-
(1983)
J Neurol Sci
, vol.61
, pp. 283-293
-
-
Miyata, S.1
Nakamura, S.2
Nagata, H.3
Kameyama, M.4
|