Enhanced preclinical efficacy of tamoxifen developed as alginate-cysteine/disulfide bond reduced albumin nanoparticles

International Journal of Pharmaceutics

Volumn 436, Issue 1-2, 2012, Pages 574-581

  Martinez A ^a   Muniz E ^a   Iglesias, I ^a   Teijon J M ^a   Blanco, M D ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Alginate cysteine; Bovine serum albumin; Breast cancer; Nanoparticles; Tamoxifen; Xenograft tumor

Indexed keywords

AFIMOXIFENE; ALBUMIN; ALGINIC ACID; BOVINE SERUM ALBUMIN; CYSTEINE; NANOPARTICLE; PLACEBO; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR XENOGRAFT;

ALGINATES; ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; CELL LINE, TUMOR; CYSTEINE; DISULFIDES; FEMALE; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; MICE; MICE, NUDE; NANOPARTICLES; NEOPLASMS; OVARY; SERUM ALBUMIN, BOVINE; TAMOXIFEN; TUMOR BURDEN; UTERUS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84865305533     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.07.045     Document Type: Article

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