Phosphorylation of Tara by Plk1 is essential for faithful chromosome segregation in mitosis

Experimental Cell Research

Volumn 318, Issue 18, 2012, Pages 2344-2352

  Zhu, Yuanyuan ^a   Wang, Chong ^b   Lan, Jianping ^c   Yu, Jian ^a   Jin, Changjiang ^d   Huang, He ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^c ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Chromosome segregation; Mitosis; Phosphorylation; Plk1; Tara

Indexed keywords

ALANINE; CYCLIN B; HISTONE H3; POLO LIKE KINASE 1; PROTEIN; THREONINE; TRIO ASSOCIATED REPEAT ON ACTIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CENTROSOME; CHROMOSOME SEGREGATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METAPHASE; MITOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

EID: 84865297929     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2012.07.001     Document Type: Article

References (34)

1. Compton D.A. Spindle assembly in animal cells. Annu. Rev. Biochem. 2000, 69:95-114.
2. Katayama H., Sasai K., Kawai H., Yuan Z.M., Bondaruk J., Suzuki F., Fujii S., Arlinghaus R.B., Czerniak B.A., Sen S. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nat. Genet. 2004, 36:55-62.
3. Saunders W.S., Shuster M., Huang X., Gharaibeh B., Enyenihi A.H., Petersen I., Gollin S.M. Chromosomal instability and cytoskeletal defects in oral cancer cells. Proc. Natl. Acad. Sci. USA 2000, 97:303-308.
4. Okada S., Ouchi T. Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization. J. Biol. Chem. 2003, 278:2015-2020.
5. Dodson H., Bourke E., Jeffers L.J., Vagnarelli P., Sonoda E., Takeda S., Earnshaw W.C., Merdes A., Morrison C. Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM. EMBO J. 2004, 23:3864-3873.
6. Kramer A., Neben K., Ho A.D. Centrosome replication, genomic instability and cancer. Leukemia 2002, 16:767-775.
7. Lingle W.L., Lukasiewicz K., Salisbury J.L. Deregulation of the centrosome cycle and the origin of chromosomal instability in cancer. Adv. Exp. Med. Biol. 2005, 570:393-421.
8. Seipel K., O'Brien S.P., Iannotti E., Medley Q.G., Streuli M. Tara, a novel F-actin binding protein, associates with the Trio guanine nucleotide exchange factor and regulates actin cytoskeletal organization. J. Cell Sci. 2001, 114:389-399.
9. Seipel K., Medley Q.G., Kedersha N.L., Zhang X.A., O'Brien S.P., Serra-Pages C., Hemler M.E., Streuli M. Trio amino-terminal guanine nucleotide exchange factor domain expression promotes actin cytoskeleton reorganization, cell migration and anchorage-independent cell growth. J. Cell Sci. 1999, 112:1825-1834.
10. O'Brien S.P., Seipel K., Medley Q.G., Bronson R., Segal R., Streuli M. Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos. Proc. Natl. Acad. Sci. USA 2000, 97:12074-12078.
11. Yu J., Lan J., Zhu Y., Li X., Lai X., Xue Y., Jin C., Huang H. The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara. Biochem. Biophys. Res. Commun. 2008, 367:805-812.
12. Dai W., Wang X. Grabbing Plk1 by the PBD. Mol. Cell 2006, 24:489-490.
13. Zhou T., Aumais J.P., Liu X., Yu-Lee L.Y., Erikson R.L. A role for Plk1 phosphorylation of NudC in cytokinesis. Dev. Cell 2003, 5:127-138.
14. Lowery D.M., Lim D., Yaffe M.B. Structure and function of Polo-like kinases. Oncogene 2005, 24:248-259.
15. Seki A., Coppinger J.A., Jang C.Y., Yates J.R., Fang G. Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry. Science 2008, 320:1655-1658.
16. Jang C.Y., Coppinger J.A., Seki A., Yates J.R., Fang G. Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a. J. Cell Sci. 2009, 122:1334-1341.
17. Spankuch B., Kurunci-Csacsko E., Kaufmann M., Strebhardt K. Rational combinations of siRNAs targeting Plk1 with breast cancer drugs. Oncogene 2007, 26:5793-5807.
18. Zhao C., Gong L., Li W., Chen L. Overexpression of Plk1 promotes malignant progress in human esophageal squamous cell carcinoma. J. Cancer Res. Clin. Oncol. 2010, 136:9-16.
19. Takahashi T., Sano B., Nagata T., Kato H., Sugiyama Y., Kunieda K., Kimura M., Okano Y., Saji S. Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers. Cancer Sci. 2003, 94:148-152.
20. Gleixner K.V., Ferenc V., Peter B., Gruze A., Meyer R.A., Hadzijusufovic E., Cerny-Reiterer S., Mayerhofer M., Pickl W.F., Sillaber C., Valent P. Polo-like kinase 1 (Plk1) as a novel drug target in chronic myeloid leukemia: overriding imatinib resistance with the Plk1 inhibitor BI 2536. Cancer Res. 2010, 70:1513-1523.
21. Yamada S., Ohira M., Horie H., Ando K., Takayasu H., Suzuki Y., Sugano S., Hirata T., Goto T., Matsunaga T., Hiyama E., Hayashi Y., Ando H., Suita S., Kaneko M., Sasaki F., Hashizume K., Ohnuma N., Nakagawara A. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. Oncogene 2004, 23:5901-5911.
22. Weichert W., Denkert C., Schmidt M., Gekeler V., Wolf G., Kobel M., Dietel M., Hauptmann S. Polo-like kinase isoform expression is a prognostic factor in ovarian carcinoma. Br. J. Cancer 2004, 90:815-821.
23. Schmit T.L., Zhong W., Setaluri V., Spiegelman V.S., Ahmad N. Targeted depletion of Polo-like kinase (Plk) 1 through lentiviral shRNA or a small-molecule inhibitor causes mitotic catastrophe and induction of apoptosis in human melanoma cells. J. Invest. Dermatol. 2009, 129:2843-2853.
24. Strebhardt K., Ullrich A. Targeting polo-like kinase 1 for cancer therapy. Nat. Rev. Cancer 2006, 6:321-330.
25. Wang C., Yu J., Yuan K., Lan J., Jin C., Huang H. Plk1-mediated mitotic phosphorylation of PinX1 regulates its stability. Eur. J. Cell Biol. 2010, 89:748-756.
26. Li X., Lan J., Zhu Y., Yu J., Dou Z., Huang H. Expression, purification, and characterization of Tara, a novel telomere repeat-binding factor 1 (TRF1)-binding protein. Protein Expression Purif. 2007, 55:84-92.
27. Yuan K., Hu H., Guo Z., Fu G., Shaw A.P., Hu R., Yao X. Phospho-regulation of HsCdc14A By Polo-like kinase 1 is essential for mitotic progression. J. Biol. Chem. 2007, 282:27414-27423.
28. Yao X., Abrieu A., Zheng Y., Sullivan K.F., Cleveland D.W. CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nat. Cell. Biol. 2000, 2:484-491.
29. Yang Y., Wu F., Ward T., Yan F., Wu Q., Wang Z., McGlothen T., Peng W., You T., Sun M., Cui T., Hu R., Dou Z., Zhu J., Xie W., Rao Z., Ding X., Yao X. Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore. J. Biol. Chem. 2008, 283:26726-26736.
30. Xue Y., Ren J., Gao X., Jin C., Wen L., Yao X. GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol. Cell Proteomics 2008, 7:1598-1608.
31. Seki A., Coppinger J.A., Du H., Jang C.Y., Yates J.R., Fang G. Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression. J. Cell Biol. 2008, 181:65-78.
32. Lee Y.J., Kim E.H., Lee J.S., Jeoung D., Bae S., Kwon S.H., Lee Y.S. HSF1 as a mitotic regulator: phosphorylation of HSF1 by Plk1 is essential for mitotic progression. Cancer Res. 2008, 68:7550-7560.
33. Wu Z.Q., Yang X., Weber G., Liu X. Plk1 phosphorylation of TRF1 is essential for its binding to telomeres. J. Biol. Chem. 2008, 283:25503-25513.
34. Mamely I., van Vugt M.A., Smits V.A., Semple J.I., Lemmens B., Perrakis A., Medema R.H., Freire R. Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery. Curr. Biol. 2006, 16:1950-1955.