Transferrin-conjugated boron nitride nanotubes: Protein grafting, characterization, and interaction with human endothelial cells

International Journal of Pharmaceutics

Volumn 436, Issue 1-2, 2012, Pages 444-453

  Ciofani, Gianni ^a   Del Turco, Serena ^b   Genchi, Giada Graziana ^a,c   D'Alessandro, Delfo ^d   Basta, Giuseppina ^b   Mattoli, Virgilio ^a  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^b INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^c SCUOLA SUPERIORE SANT ANNA   (Italy)

^d UNIVERSITY OF PISA   (Italy)

Author keywords

Boron nitride nanotubes; Cell targeting; HUVECs; Selective up take; Transferrin

Indexed keywords

BORON NITRIDE NANOTUBE; TRANSFERRIN; UREA;

ARTICLE; BIOCOMPATIBILITY; CELL INTERACTION; CELL STRUCTURE; CHEMICAL MODIFICATION; CONFOCAL LASER MICROSCOPY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; NANOTECHNOLOGY; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SPECTROPHOTOMETRY; TRANSMISSION ELECTRON MICROSCOPY; UMBILICAL VEIN ENDOTHELIAL CELL; ZETA POTENTIAL;

BIOLOGICAL TRANSPORT; BORON COMPOUNDS; CELL SURVIVAL; CELLS, CULTURED; DRUG CARRIERS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOTUBES; RECEPTORS, TRANSFERRIN; TRANSFERRIN;

EID: 84865295074     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.06.037     Document Type: Article

References (46)

1. N.J. Abbott, A.A. Patabendige, D.E. Dolman, S.R. Yusof, and D.J. Begley Structure and function of the blood-brain barrier Neurobiol. Dis. 37 2010 13 25
2. L. Calucci, G. Ciofani, D. De Marchi, C. Forte, A. Menciassi, L. Menichetti, and V. Positano Boron nitride nanotubes as T2-weighted MRI contrast agents J. Phys. Chem. Lett. 1 2010 2561 2565
3. J. Capala, B.H. Stenstam, K. Sköld, P. Munck af Rosenschöld, V. Giusti, C. Persson, E. Wallin, A. Brun, L. Franzen, J. Carlsson, L. Salford, C. Ceberg, B. Persson, L. Pellettieri, and R. Henriksson Boron neutron capture therapy for glioblastoma multiforme: clinical studies in Sweden J. Neurooncol. 62 2003 135 144
4. X. Chen, P. Wu, M. Rousseas, D. Okawa, Z. Gartner, A. Zettl, and C.R. Bertozzi Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells J. Am. Chem. Soc. 131 2009 890 891
5. G. Ciofani, V. Raffa, A. Menciassi, and A. Cuschieri Boron nitride nanotubes: an innovative tool for nanomedicine Nano Today 4 2009 8 10
6. G. Ciofani, G.G. Genchi, I. Liakos, A. Athanassiou, D. Dinucci, F. Chiellini, and V. Mattoli A simple approach to covalent functionalization of boron nitride nanotubes J. Colloid. Interf. Sci. 374 2012 308 314
7. T.R. Daniels, E. Bernabeu, J.A. Rodríguez, S. Patel, M. Kozman, D.A. Chiappetta, E. Holler, J.Y. Ljubimova, G. Helguera, and M.L. Penichet The transferrin receptor and the targeted delivery of therapeutic agents against cancer Biochim. Biophys. Acta 1820 2012 291 317
8. A.G. de Boer, I.C. van der Sandt, and P.J. Gaillard The role of drug transporters at the blood-brain barrier Annu. Rev. Pharmacol. Toxicol. 43 2003 629 656
9. R. De Caterina, H. Tanaka, T. Nakagawa, P.J. Hauptman, and P. Libby The direct effect of injectable cyclosporine and its vehicle, cromophor, on endothelial vascular cell adhesion molecule-1 expression. Ricinoleic acid inhibits coronary artery endothelial activation Transplantation 60 1995 270 275
10. S. Del Turco, G. Basta, G. Lazzerini, M. Evangelista, G. Rainaldi, P. Tanganelli, M. Camera, E. Tremoli, and R. De Caterina Parallel decrease of tissue factor surface exposure and increase of tissue factor microparticle release by the n-3 fatty acid docosahexaenoate in endothelial cells Thromb. Haemost. 98 2007 210-209
11. U. Dembereldorj, E.O. Ganbold, J.H. Seo, S.Y. Lee, S.I. Yang, and S.W. Joo Conformational changes of proteins adsorbed onto ZnO nanoparticle surfaces investigated by concentration-dependent infrared spectroscopy Vib. Spectrosc. 59 2012 23 28
12. F. Dilnawaz, A. Singh, and S.K. Sahoo Transferrin-conjugated curcumin-loaded superparamagnetic iron oxide nanoparticles induce augmented cellular uptake and apoptosis in K562 cells Acta Biomater. 8 2012 704 719
13. Z. Gao, C.Y. Zhi, Y. Bando, D. Golberg, and T. Serizawa Isolation of individual boron nitride nanotubes via peptide wrapping J. Am. Chem. Soc. 132 2010 4976 4977
14. L. Horvath, A. Magrez, D. Golberg, C.Y. Zhi, Y. Bando, R. Smajda, E. Horvath, L. Forro, and B. Schwaller In Vitro Investigation of the Cellular Toxicity of Boron Nitride Nanotubes ACS Nano 5 2011 3800 3810
15. W.A. Jefferies, M.R. Brandon, S.V. Hunt, A.F. Williams, K.C. Gatter, and D.Y. Mason Transferrin receptor on endothelium of brain capillaries Nature 312 1984 162 163
16. Y.Y. Jiang, C. Liu, M.H. Hong, S.J. Zhu, and Y.Y. Pei Tumor cell targeting of transferrin-PEG TNF-alpha conjugate via a receptor-mediated delivery system: design, synthesis, and biological evaluation Bioconjug. Chem. 18 2007 41 49
17. M. Kaasalainen, E. Mäkilä, J. Riikonen, M. Kovalainen, K. Järvinen, K.H. Herzig, V.P. Lehto, and J. Salonen Effect of isotonic solutions and peptide adsorption on zeta potential of porous silicon nanoparticle drug delivery formulations Int. J. Pharmaceut. 431 2012 230 236
18. I.A. Kaltashov, C.E. Bobst, M. Zhang, R. Leverence, and D.R. Gumerov Transferrin as a model system for method development to study structure, dynamics and interactions of metalloproteins using mass spectrometry BBA-Gen. Subjects 1820 2012 417 426
19. 10 B concentration predictions and dosimetric consequences J. Neurooncol. 62 2003 171 186
20. C.H. Lee, J. Wang, V.K. Kayatsha, J.Y. Huang, and Y.K. Yap Effective growth of boron nitride nanotubes by thermal chemical vapor deposition Nanotechnology 19 2008 455605
21. H.Y. Li, and Z.M. Qian Transferrin/transferrin receptor-mediated drug delivery Med. Res. Rev. 22 2002 225 250
22. J.L. Li, D. Day, and M. Gu Ultra-low energy threshold for photothermal therapy of cancer using transferrin-conjugated gold nanorods Adv. Mater. 20 2008 3886-3871
23. L. Li, W. Feng, and P. Ji Protein adsorption on functionalized multiwalled carbon nanotubes with amino-cyclodextrin Bioeng.; Food,Nat. Prod. 57 2011 3507 3513
24. Z. Pang, H. Gao, Y. Yu, J. Chen, L. Guo, J. Ren, Z. Wen, J. Su, and X. Jiang Brain delivery and cellular internalization mechanisms for transferrin conjugated biodegradable polymersomes Int. J. Pharmaceut. 415 2011 284 292
25. W.M. Pardridge Vector-mediated drug delivery to the brain Adv. Drug. Deliver. Rev. 36 1999 299 321
26. W.M. Pardridge Blood-brain barrier delivery Drug Discov. Today 12 2007 54 61
27. J.H. Park, J. Park, U. Dembereldorj, K. Cho, K. Lee, S.I. Yang, S.Y. Lee, and S.W. Joo Raman detection of localized transferrin-coated gold nanoparticles inside a single cell Anal. Bioanal. Chem. 401 2011 1631 1639
28. P. Prieto, B.J. Blaauboer, A.G. de Boer, M. Boveri, R. Cecchelli, C. Clemedson, S. Coecke, A. Forsby, H.J. Galla, P. Garberg, J. Greenwood, A. Price, and H. Tähti Blood-brain barrier in vitro models and their application in toxicology. The report and recommendations of ECVAM Workshop 49 Altern. Lab Anim. 32 2004 37 50
29. Z. Qian, H. Li, H. Sun, and K. Ho Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway Pharmacol. Rev. 54 2002 561 587
30. K. Rausch, A. Reuter, K. Fischer, and M. Schmidt Evaluation of nanoparticle aggregation in human blood serum Biomacromolecules 11 2010 2836 2839
31. R.M. Silverstein, G. Clayton Bassler, and T.C. Morrill Spectrometric Identification of Organic Compounds 1991 Wiley
32. 99 mTc: preparation, physicochemical characterization, biodistribution study, and scintigraphic imaging in Swiss mice Int. J. Pharmaceut. 423 2012 489 495
33. C.M. Stoscheck Quantitation of protein Method Enzymol. 182 1990 50 69
34. C.C. Tang, M.L. la Chapelle, P. Li, Y.M. Liu, H.Y. Dang, and S.S. Fan Catalytic growth of nanotube and nanobamboo structures of boron nitride Chem. Phys. Lett. 342 2001 492 496
35. N.T.K. Thanh, and L.A.W. Green Functionalisation of nanoparticles for biomedical applications Nano Today 5 2010 213 230
36. K. Ulbrich, T. Hekmatara, E. Herbert, and J. Kreuter Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood-brain barrier (BBB) Eur. J. Pharm. Biopharm. 71 2009 251 256
37. P.H. Yang, X.S. Sun, J.F. Chiu, H.Z. Sun, and Q.Y. He Transferrin-mediated gold nanoparticle cellular uptake Bioconjugate Chem. 16 2005 494 496
38. K.T. Yong, J. Qian, I. Roy, H.H. Lee, E.J. Bergey, K.M. Tramposch, S. He, M.T. Swihart, A. Maitra, and P.N. Prasad Quantum rod bioconjugates as targeted probes for confocal and two-photon fluorescence imaging of cancer cells Nano Lett. 7 2007 761 765
39. C.Y. Zhi, Y. Bando, C.C. Tang, R.G. Xie, T. Sekiguchi, and D. Golberg Perfectly dissolved boron nitride nanotubes due to polymer wrapping J. Am. Chem. Soc. 127 2005 15996 15997
40. C.Y. Zhi, Y. Bando, C. Tang, S. Honda, K. Sato, H. Kuwahara, and D. Golberg Covalent functionalization: towards soluble multiwalled boron nitride nanotubes Angew. Chem. Int. Edit. 44 2005 7932 7935
41. C.Y. Zhi, Y. Bando, C. Tang, and D. Golberg Immobilization of proteins on boron nitride nanotubes J. Am. Chem. Soc. 127 2005 17144 17145
42. C.Y. Zhi, Y. Bando, C.C. Tang, D. Golberg, R. Xie, and T. Sekiguchi Phonon characteristics and cathodolumininescence of boron nitride nanotubes Appl. Phys. Lett. 86 2005 213110
43. C.Y. Zhi, Y. Bando, T. Terao, C.C. Tang, H. Kuwahara, and D. Golberg Chemically activated boron nitride nanotubes Chem. Asian J. 4 2009 1536 1540
44. C.Y. Zhi, Y. Bando, C.C. Tang, and D. Golberg Boron nitride nanotubes Mater. Sci. Eng. R-Rep. 70 2010 92 111
45. C.Y. Zhi, N. Hanagata, Y. Bando, and D. Golberg Dispersible shortened boron nitride nanotubes with improved molecule-loading capacity Chem. Asian J. 6 2011 2530 2535
46. C.Y. Zhi, W. Meng, T. Yamazaki, Y. Bando, D. Golberg, C. Tang, and N. Hanagata BN nanospheres as CpG ODN carriers for activation of toll-like receptor 9 J. Mater. Chem. 21 2011 5219 5222