Pharmacokinetic modeling for boronophenylalanine-fructose mediated neutron capture therapy: 10-B concentration predictions and dosimetric consequences

Journal of Neuro-Oncology

Volumn 62, Issue 1, 2003, Pages 171-186

  Kiger III, W S ^a,b   Palmer, M R ^b   Riley, K J ^a   Zamehof, R G ^b   Busse, P M ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Boron concentration prediction; Boron neutron capture therapy (BNCT); Boronophenylalanine fructose (BPA F); Pharmacokinetic model

Indexed keywords

4 BORONOPHENYLALANINE FRUCTOSE; BORON 10; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; BORON; BORON DERIVATIVE;

ADULT; AGED; ANALYTICAL ERROR; ARTICLE; BLOOD SAMPLING; BRAIN CANCER; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARTMENT MODEL; CONSTANTS AND COEFFICIENTS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSIMETRY; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INFUSION; FEMALE; GLIOBLASTOMA; HUMAN; IRRADIATION; MALE; MATHEMATICAL MODEL; MELANOMA; NEUTRON CAPTURE THERAPY; PHASE 1 CLINICAL TRIAL; PREDICTION; RADIATION BEAM; RETROSPECTIVE STUDY; SIMULATION; BLOOD; BRAIN TUMOR; HALF LIFE TIME; METASTASIS; METHODOLOGY; PREDICTION AND FORECASTING; RADIATION DOSE; SKIN TUMOR; THEORETICAL MODEL;

BORON; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; BRAIN NEOPLASMS; GLIOBLASTOMA; HALF-LIFE; HUMANS; MELANOMA; MODELS, THEORETICAL; PREDICTIVE VALUE OF TESTS; RADIOTHERAPY DOSAGE; SKIN NEOPLASMS;

EID: 0038030894     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023297107525     Document Type: Article

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