Crystal structure of the Rab binding domain of OCRL1 in complex with Rab8 and functional implications of the OCRL1/Rab8 module for Lowe syndrome

Small GTPases

Volumn 3, Issue 2, 2012, Pages 107-110

  Hagemann, Nina ^a   Hou, Xiaomin ^b   Goody, Roger S ^b   Itzen, Aymelt ^b   Erdmann, Kai S ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

Biosynthetic pathway; Cilia; Endocytosis; OCRL; Rab8

Indexed keywords

OCRL1 PROTEIN; RAB PROTEIN; RAB8 PROTEIN; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DISEASE ASSOCIATION; ENDOCYTOSIS; GENE EXPRESSION REGULATION; GENE MUTATION; HUMAN; LOWE SYNDROME; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS; TRANS GOLGI NETWORK;

EID: 84865293012     PISSN: 21541248     EISSN: 21541256     Source Type: Journal    
DOI: 10.4161/sgtp.19380     Document Type: Article

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