Apparent diffusion coefficient of hyperpolarized 3He with minimal influence of the residual gas in small animals

NMR in Biomedicine

Volumn 25, Issue 9, 2012, Pages 1026-1032

  Carrero Gonzalez L ^a   Kaulisch, T ^a   Ruiz Cabello, J ^b,c   Perez Sanchez J M ^b,d   Peces Barba, G ^e   Stiller, D ^a   Rodriguez I ^b,c  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d CNRS   (France)

^e UAM)   (Spain)

Author keywords

Apparent diffusion coefficient; Hyperpolarized 3He MRI; In vivo lung imaging; Positive end expiratory pressure

Indexed keywords

APPARENT DIFFUSION COEFFICIENT; BREATH-HOLD; HYPERPOLARIZED; LUNG IMAGING; LUNG MICROSTRUCTURES; REPRODUCIBILITIES; RESIDUAL GAS; SMALL ANIMAL; STANDARD METHOD;

BIOLOGICAL ORGANS; HELIUM; MIXTURES; PHYSIOLOGICAL MODELS;

SURFACE DIFFUSION;

HELIUM; OXYGEN;

APPARENT DIFFUSION COEFFICIENT; ARTICLE; DIFFUSION COEFFICIENT; EMPHYSEMA; HELIUM OXYGEN BREATHING; HYPERPOLARIZATION; INFORMATION PROCESSING; LUNG DIFFUSION; LUNG VENTILATION; MEDICAL RECORD; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARAMETERS; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RAT; RESIDUAL VOLUME; SPECTROMETER;

ANIMALS; DIFFUSION; HELIUM; HUMANS; LUNG; MALE; POSITIVE-PRESSURE RESPIRATION; PULMONARY VENTILATION; RATS; RATS, WISTAR; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

ANIMALIA; RATTUS;

EID: 84865283773     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.2765     Document Type: Article

References (23)

1. 3He diffusion. Proc. Natl. Acad. Sci. 2000; 97: 11478-11481.
2. Peces-Barba G, Ruiz-Cabello J, Cremillieux Y, Rodriguez I, Dupuich D, Callot V, Ortega M, Rubio Arbo ML, Cortijo M, Gonzalez-Mangado N. Helium-3 MRI diffusion coefficient: correlation to morphometry in a model of mild emphysema. Eur. Respir. J. 2003; 22: 14-19.
3. Saam BT, Yablonskiy DA, Kodibagkar VD, Leawoods JC, Gierada DS, Cooper JD, Lefrak SS, Conradi MS. MR imaging of diffusion of (3)He gas in healthy and diseased lungs. Magn. Reson. Med. 2000; 44: 174-179.
4. Salerno M, de Lange EE, Altes TA, Truwit JD, Brookeman JR, Mugler JP III. Emphysema: hyperpolarized helium 3 diffusion MR imaging of the lungs compared with spirometric indexes-initial experience. Radiology 2002; 222: 252-260.
5. 3He apparent diffusion coefficients in severe chronic obstructive pulmonary disease. J. Magn. Reson. Imaging, 2007; 26: 1537-1547.
6. Fichele S, Woodhouse N, Swift AJ, Said Z, Paley MN, Kasuboski L, Mills GH, van Beek EJ, Wild JM. MRI of helium-3 gas in healthy lungs: posture related variations of alveolar size. J. Magn. Reson. Imaging, 2004; 20: 331-335.
7. Schreiber WG, Morbach AE, Stavngaard T, Gast KK, Herweling A, Sogaard LV, Windirsch M, Schmiedeskamp J, Heussel CP, Kauczor HU. Assessment of lung microstructure with magnetic resonance imaging of hyperpolarized helium-3. Respir. Physiol. Neurobiol. 2005; 148: 23-42.
8. 3He apparent diffusion coefficient MRI of the lung: reproducibility and volume dependency in healthy volunteers and patients with emphysema. J. Magn. Reson. Imaging 2008; 27: 763-770.
9. Waters B, Owers-Bradley J, Silverman M. Acinar structure in symptom-free adults by helium-3 magnetic resonance. Am. J. Respir. Crit. Care Med. 2006; 173: 847-851.
10. Gierada DS, Woods JC, Bierhals AJ, Bartel ST, Ritter JH, Choong CK, Das NA, Hong C, Pilgram TK, Chang YV, Jacob RE, Hogg JC, Battafarano RJ, Cooper JD, Meyers BF, Patterson GA, Yablonskiy DA, Conradi MS. Effects of diffusion time on short-range hyperpolarized (3)He diffusivity measurements in emphysema. J. Magn. Reson. Imaging 2009; 30: 801-808.
11. 3He diffusion MRI. J. Appl. Physiol. 2009; 107(4): 1258-1265.
12. Hirschfelder JO, Bird RB, Spotz EL. The transport properties of gases and gaseous mixtures. Chem. Rev. 1949; 44: 205-231.
13. Hirschfelder JO, Curtis CF, Bird RB. Molecular Theory of Gases and Liquids. Wiley: New York; 1954.
14. 3He in the human lung at very low magnetic fields. J. Magn. Reson. 2003; 162: 122-132.
15. Rudersdorf D. Entwicklung und Anwendung eines Beatmungssystems zur Untersuchung der Lungenfeinstruktur mittels He-3-Magnetresonanztomographie, Dissertation, Institut für Physik, Johannes Gutenberg-Universität Mainz; 2010.
16. 3He. Nucl. Instr. and Meth. A 1998; 402: 327-336.
17. 3He MRI. Magn. Reson. Med. 2010; 63: 137-150.
18. Chen XJ, Moller HE, Chawla MS, Cofer GP, Driehuys B, Hedlund LW, Johnson GA. Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part I: diffusion coefficient. Magn. Reson. Med. 1999; 42: 721-728.
19. Rodriguez I, Perez de Alejo R, Cortijo M, Ruiz-Cabello J. COMSPIRA: A common approach to spiral and radial MRI. Concepts Magn. Reson. Part B (Magn. Reson. Eng.) 2004; 20B: 40-44.
20. 3He MRI. Proceedings of the 17th Annual Meeting ISMRM, Honolulu, Hawaii, USA, 2009; 2181.
21. 3He diffusion MRI as a local in vivo morphometric tool to evaluate emphysematous rat lungs. J. Appl. Physiol. 2008; 105: 1291-1300.
22. Dugas JP, Garbow JR, Kobayashi DK, Conradi MS. Hyperpolarized (3)He MRI of mouse lung. Magn. Reson. Med. 2004; 52: 1310-1317.
23. Cereda M, Emami K, Kadlecek S, Xin Y, Mongkolwisetwara P, Profka H, Barulic A, Pickup S, Mansson S, Wollmer P, Ishii M, Deutschman CS, Rizi RR. Quantitative imaging of alveolar recruitment with hyperpolarized gas MRI during mechanical ventilation. J. Appl. Physiol. 2011; 110: 499-511.