Acinar structure in symptom-free adults by helium-3 magnetic resonance

American Journal of Respiratory and Critical Care Medicine

Volumn 173, Issue 8, 2006, Pages 847-851

  Waters, Barnaby ^b   Owers Bradley, John ^b   Silverman, Mike ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b NONE

Author keywords

Age; Diffusion; Hyperpolarized noble gas; Smoking

Indexed keywords

HELIUM;

ADULT; AGED; AGING; ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DIFFUSION WEIGHTED IMAGING; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPERPOLARIZATION; LUNG DIFFUSION; LUNG INFLATION; LUNG STRUCTURE; LUNG VOLUME; MALE; MORPHOMETRICS; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SPIROMETRY;

ADOLESCENT; ADULT; AGE FACTORS; AGED; DIFFUSION; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; FORCED EXPIRATORY VOLUME; HELIUM; HUMANS; ISOTOPES; LUNG; MALE; MIDDLE AGED; REFERENCE VALUES;

EID: 33646360205     PISSN: 1073449X     EISSN: 1073449X     Source Type: Journal    
DOI: 10.1164/rccm.200411-1595OC     Document Type: Article

References (30)

1. Brand P, Rieger C, Beinert T, Heyder J. Aerosol derived airway morphometry in healthy subjects. Eur Respir J 1995;8:1639-1646.
2. Zeman KL, Bennett WD. Measuring alveolar dimensions at total lung capacity by aerosol-derived airway morphometry. J Aerosol Med 1995;8:135-147.
3. Thurlbeck WM. Postnatal human lung growth. Thorax 1982;37:564-571.
4. Langston C, Kida K, Reed M, Thurlbeck WM. Human lung growth in late gestation and in the neonate. Am Rev Respir Dis 1984;129:607-613.
5. Angus GE, Thurlbeck WM. Number of alveoli in the human lung. J Appl Physiol 1972;32:483-485.
6. Ochs M, Nyengaard JR, Jung A, Knudsen L, Voigt M, Wahlers T, Richter J, Gundersen HJ. The number of alveoli in the human lung. Am J Respir Crit Care Med 2004;169:120-124.
7. Armour J, Donnelly PM, Bye PT. The large lungs of elite swimmers: an increased alveolar number? Eur Respir J 1993;6:237-247.
8. Thurlbeck WM. The internal surface area of nonemphysematous lungs. Am Rev Respir Dis 1967;95:765-773.
9. Gillooly M, Lamb D. Airspace size in lungs of lifelong non-smokers: effect of age and sex. Thorax 1993;48:39-43.
10. Colebatch HJ, Ng CK. Estimating alveolar surface area during life. Respir Physiol 1992;88:163-170.
11. Gillooly M, Lamb D. Microscopic emphysema in relation to age and smoking habit. Thorax 1993;48:491-495.
12. Massaro GD, Massaro D. Retinoic acid treatment partially rescues failed septation in rats and in mice. Am J Physiol Lung Cell Mol Physiol 2000;278:L955-L960.
13. Hind M, Maden M. Retinoic acid induces alveolar regeneration in the adult mouse lung. Eur Respir J 2004;23:20-27.
14. 3He gas. Magn Reson Med 1995;33:271-275.
15. Peces-Barba G, Ruiz-Cabello J, Cremillieux Y, Rodriguez I, Dupuich D, Callot V, Ortega M, Rubio Arbo ML, Cortijo M, Gonzalez-Mangado N. Helium-3 MRI diffusion coefficient: correlation to morphometry in a model of mild emphysema. Eur Respir J 2003;22:14-19.
16. Yablonskiy DA, Sukstanskii AL, Leawoods JC, Gierada DS, Bretthorst GL, Lefrak SS, Cooper JD, Conradi MS. Quantitative in vivo assessment of lung microstructure at the alveolar level with hyperpolarized 3He diffusion MRI. Proc Natl Acad Sci USA 2002;99:3111-3116.
17. Salerno M, de Lange EE, Altes TA, Truwit JD, Brookeman JR, Mugler JP III. Emphysema: hyperpolarized helium 3 diffusion MR imaging of the lungs compared with spirometric indexes - initial experience. Radiology 2002;222:252-260.
18. Samee S, Altes T, Powers P, de Lange EE, Knight-Scott J, Rakes G, Mugler JP III, Ciambotti JM, Alford BA, Brookeman JR, et al. Imaging the lungs in asthmatic patients by using hyperpolarized helium-3 magnetic resonance: assessment of response to methacholine and exercise challenge. J Allergy Clin Immunol 2003;111:1205-1211.
19. Wild JM, Paley MN, Kasuboski L, Swift A, Fichele S, Woodhouse N, Griffiths PD, van Beek EJ. Dynamic radial projection MRI of inhaled hyperpolarised 3He gas. Magn Reson Med 2003;49:991-997.
20. 3He in the lungs. Proceedings of the 10th annual meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, 2002.
21. 3He gas. J Magn Reson Imaging 2003;17:142-146.
22. Waters BA, Owers-Bradley JR, Silverman M. Alveolar size in symptom-free adults. Proceedings of the British Chapter of the International Society for Magnetic Resonance in Medicine Conference, 2004; Oxford, UK.
23. 3He-magnetic resonance. Proceedings of European Respiratory Society Annual Congress, 2005; Copenhagen, Denmark.
24. Waters BA, Owers-Bradley JR, Silverman M. Alveolar size in symptom-free adults. Proceedings of International Society for Magnetic Resonance in Medicine, 2005; Miami, Florida.
25. Medical Section of the American Lung Association. Standardization of spirometry, 1994 update, American Thoracic Society. Am J Respir Crit Care Med 1995;152:1107-1136.
26. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault J-C. Lung volumes and forced ventilatory flows: report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal: official Statement of the European Respiratory Society. Eur Respir J 1993;6:5-40.
27. Cotes JE. Lung function assessment and application in medicine, 3rd ed. Oxford, UK: Blackwell Scientific Publications; 1975.
28. 3He. Magn Reson Med 1996;36:192-196.
29. Schreiber WG, Morbach AE, Stavngaard T, Gast KK, Herweling A, Søgaard LV, Windirsch M, Schmiedeskamp J, Heussel CP, Kauczor HU. Assessment of lung microstructure with magnetic resonance imaging of hyperpolarized Helium-3. Respir Physiol Neurobiol 2005;148:23-42.
30. Cosio MG, Shiner RJ, Saetta M, Wang NS, King M, Ghezzo H, Angus E. Alveolar fenestrae in smokers: relationship with light microscopic and functional abnormalities. Am Rev Respir Dis 1986;133:126-131.