The unusual case of porcupine

Science

Volumn 337, Issue 6097, 2012, Pages 922-923

  Lum, Lawrence ^a   Clevers, Hans ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AXIN; GHRELIN; SONIC HEDGEHOG PROTEIN; TANKYRASE; WNT PROTEIN; ANTINEOPLASTIC AGENT; DNA BINDING PROTEIN; ENZYME INHIBITOR; MEMBRANE PROTEIN; ONCOPROTEIN; PALMITIC ACID; PORCN PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; RNF43 PROTEIN, HUMAN; STK11 PROTEIN, HUMAN;

BIOACCUMULATION; CANCER; ORGANIC COMPOUND; POLLUTION EFFECT; RODENT; SIGNALING; TOXICITY;

BASAL CELL CARCINOMA; CANCER CELL; COLORECTAL CANCER; DISTANT METASTASIS; DROSOPHILA; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; HUMAN; NONHUMAN; PALMITOYLATION; PORCUPINE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; WNT SIGNALING PATHWAY; ARTICLE; DRUG ANTAGONISM; DRUG DEVELOPMENT; DRUG EFFECT; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; MUTATION; NEOPLASM; PHASE 1 CLINICAL TRIAL (TOPIC);

ANTINEOPLASTIC AGENTS; CLINICAL TRIALS, PHASE I AS TOPIC; DNA-BINDING PROTEINS; DRUG DISCOVERY; ENZYME INHIBITORS; HUMANS; MEMBRANE PROTEINS; MOLECULAR TARGETED THERAPY; MUTATION; NEOPLASMS; ONCOGENE PROTEINS; PALMITIC ACID; PROTEIN-SERINE-THREONINE KINASES; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84865281576     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1228179     Document Type: Review

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