Thoracic Aortic Aneurysm (TAAD)-causing Mutation in Actin Affects Formin Regulation of Polymerization

Journal of Biological Chemistry

Volumn 287, Issue 34, 2012, Pages 28398-28408

  Malloy, Lindsey E ^a   Wen, Kuo Kuang ^a   Pierick, Alyson R ^a   Wedemeyer, Elesa W ^a   Bergeron, Sarah E ^a   Vanderpool, Nicole D ^a   McKane, Melissa ^a   Rubenstein, Peter A ^a   Bartlett, Heather L ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN CYTOSKELETON; ACTIN FILAMENT; ACTIN POLYMERIZATION; AORTIC ANEURYSMS; AUTOSOMAL DOMINANTS; BIOCHEMICAL EFFECTS; CRITICAL CONCENTRATION; CYTOSKELETAL; F-ACTIN; FILAMENT INSTABILITY; IN-VITRO; LATRUNCULIN A; MODEL SYSTEM; MOYAMOYA DISEASE; MUTANT CELLS; PATENT DUCTUS ARTERIOSUS; PHALLOIDIN; SACCHAROMYCES CEREVISIAE YEAST; SMOOTH MUSCLE ACTINS; TRANSIENT EXPOSURE; VASCULAR SMOOTH MUSCLE CELLS; WILD TYPES; YEAST ACTIN;

BLOOD VESSELS; NUCLEATION; POLYMERIZATION; YEAST;

PROTEINS;

ACTIN; FUNGAL PROTEIN; LATRUNCULIN A; PHALLOIDIN; PROTEIN; PROTEIN BNI1; PROTEIN FORMIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ARTICLE; CELL GROWTH; CELL SIZE; CONCENTRATION (PARAMETERS); DEPOLYMERIZATION; GENE MUTATION; GROWTH INHIBITION; HISTOLOGY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; SMOOTH MUSCLE FIBER; THORACIC AORTA ANEURYSM; VASCULAR SMOOTH MUSCLE;

ACTIN CYTOSKELETON; ACTINS; AMINO ACID SUBSTITUTION; AORTIC ANEURYSM; BICYCLO COMPOUNDS, HETEROCYCLIC; HUMANS; MICROFILAMENT PROTEINS; MODELS, BIOLOGICAL; MUTATION, MISSENSE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; THIAZOLIDINES;

EID: 84865230729     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.371914     Document Type: Article

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