Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal β-oxidation of unsaturated fatty acids

Journal of Biological Chemistry

Volumn 287, Issue 34, 2012, Pages 28956-28965

  Hua, Tian ^a   Wu, Dong ^a,b   Ding, Wei ^a   Wang, Jiangyun ^a   Shaw, Neil ^c   Liu, Zhi Jie ^a,b  

^a INSTITUTE OF BIOPHYSICS   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

^c NANKAI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ALIPHATIC CARBON; ASPARTATES; BIOCHEMICAL STUDIES; IN-VITRO; MOLECULAR LEVELS; STRUCTURAL EVIDENCE; TERNARY COMPLEX; VERY LONG-CHAIN FATTY ACIDS; VERY LONG-CHAIN POLYUNSATURATED FATTY ACIDS; WATER MOLECULE;

AMINO ACIDS; CYTOLOGY; MITOCHONDRIA; MOLECULES; OXIDATION; POLYUNSATURATED FATTY ACIDS; SUBSTRATES;

ENZYME ACTIVITY;

2,4 DIENOYL COENZYME A REDUCTASE (NADPH); NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNSATURATED FATTY ACID;

ARTICLE; BASE PAIRING; CATALYSIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; FATTY ACID OXIDATION; HUMAN; HYDROGEN BOND; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ACYL COENZYME A; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; FATTY ACIDS, UNSATURATED; HUMANS; NADP; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PEROXISOMES; PROTEIN STRUCTURE, TERTIARY;

EID: 84865217086     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.385351     Document Type: Article

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