Coronary artery remodeling in a model of left ventricular pressure overload is influenced by platelets and inflammatory cells

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Yang, Fanmuyi ^a   Dong, Anping ^a   Mueller, Paul ^a   Caicedo, Jessica ^a   Sutton, Alyssa Moore ^a   Odetunde, Juliana ^a   Barrick, Cordelia J ^b   Klyachkin, Yuri M ^a   Abdel Latif, Ahmed ^a,c   Smyth, Susan S ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c LEXINGTON VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY ARTERY REMODELING; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE FIBROSIS; HISTOPATHOLOGY; INFLAMMATORY CELL; LEFT CORONARY ARTERY; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; T LYMPHOCYTE; THROMBOCYTE; THROMBOCYTE AGGREGATION; THROMBOCYTOPENIA; UPREGULATION; WILD TYPE;

ANIMALS; BLOOD PLATELETS; CORONARY VESSELS; ECHOCARDIOGRAPHY, DOPPLER; FLOW CYTOMETRY; HEART VENTRICLES; MACROPHAGES; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; POLYMERASE CHAIN REACTION; T-LYMPHOCYTES;

EID: 84865176076     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040196     Document Type: Article

References (63)

1. Rohr S, ((2009)) Myofibroblasts in diseased hearts: new players in cardiac arrhythmias? Heart Rhythm 6:: 848--856.
2. Nicoletti A, Michel JB, ((1999)) Cardiac fibrosis and inflammation: interaction with hemodynamic and hormonal factors. Cardiovasc Res 41:: 532--543.
3. Kwon DH, Smedira NG, Rodriguez ER, Tan C, Setser R, et al. ((2009)) Cardiac magnetic resonance detection of myocardial scarring in hypertrophic cardiomyopathy: correlation with histopathology and prevalence of ventricular tachycardia. J Am Coll Cardiol 54:: 242--249.
4. Dellsperger KC, Marcus ML, ((1990)) Effects of left ventricular hypertrophy on the coronary circulation. Am J Cardiol 65:: 1504--1510.
5. Bache RJ, ((1988)) Effects of hypertrophy on the coronary circulation. Prog Cardiovasc Dis 30:: 403--440.
6. Dellsperger KC, Marcus ML, ((1988)) The effects of pressure-induced cardiac hypertrophy on the functional capacity of the coronary circulation. Am J Hypertens 1:: 200--207.
7. Marcus ML, Gascho JA, Mueller TM, Eastham C, Wright CB, et al. ((1981)) The effects of ventricular hypertrophy on the coronary circulation. Basic Res Cardiol 76:: 575--581.
8. Marcus ML, Mueller TM, Gascho JA, Kerber RE, ((1979)) Effects of cardiac hypertrophy secondary to hypertension on the coronary circulation. Am J Cardiol 44:: 1023--1028.
9. Bache RJ, Wright L, Laxson DD, Dai XZ, ((1990)) Effect of coronary stenosis on myocardial blood flow during exercise in the chronically pressure-overloaded hypertrophied left ventricle. Circulation 81:: 1967--1973.
10. Kagitani S, Ueno H, Hirade S, Takahashi T, Takata M, et al. ((2004)) Tranilast attenuates myocardial fibrosis in association with suppression of monocyte/macrophage infiltration in DOCA/salt hypertensive rats. J Hypertens 22:: 1007--1015.
11. Kai H, Kuwahara F, Tokuda K, Imaizumi T, ((2005)) Diastolic dysfunction in hypertensive hearts: roles of perivascular inflammation and reactive myocardial fibrosis. Hypertens Res 28:: 483--490.
12. Kuwahara F, Kai H, Tokuda K, Niiyama H, Tahara N, et al. ((2003)) Roles of intercellular adhesion molecule-1 in hypertensive cardiac remodeling. Hypertension 41:: 819--823.
13. Kuwahara F, Kai H, Tokuda K, Takeya M, Takeshita A, et al. ((2004)) Hypertensive myocardial fibrosis and diastolic dysfunction: another model of inflammation? Hypertension 43:: 739--745.
14. Ishimaru K, Ueno H, Kagitani S, Takabayashi D, Takata M, et al. ((2007)) Fasudil attenuates myocardial fibrosis in association with inhibition of monocyte/macrophage infiltration in the heart of DOCA/salt hypertensive rats. J Cardiovasc Pharmacol 50:: 187--194.
15. Zernecke A, Liehn EA, Gao JL, Kuziel WA, Murphy PM, et al. ((2006)) Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10. Blood 107:: 4240--4243.
16. Gawaz M, ((2004)) Role of platelets in coronary thrombosis and reperfusion of ischemic myocardium. Cardiovasc Res 61:: 498--511.
17. van Gils JM, Zwaginga JJ, Hordijk PL, ((2008)) Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases. J Leukoc Biol.
18. Galkina E, Ley K, ((2007)) Vascular adhesion molecules in atherosclerosis. Arterioscler Thromb Vasc Biol 27:: 2292--2301.
19. Gleissner CA, von Hundelshausen P, Ley K, ((2008)) Platelet chemokines in vascular disease. Arterioscler Thromb Vasc Biol 28:: 1920--1927.
20. McNicol A, Israels SJ, ((2008)) Beyond hemostasis: the role of platelets in inflammation, malignancy and infection. Cardiovasc Hematol Disord Drug Targets 8:: 99--117.
21. Kleinschnitz C, Pozgajova M, Pham M, Bendszus M, Nieswandt B, et al. ((2007)) Targeting platelets in acute experimental stroke: impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding. circulation 115:: 2323--2330.
22. Nieswandt B, Aktas B, Moers A, Sachs UJ, ((2005)) Platelets in atherothrombosis: lessons from mouse models. J Thromb Haemost 3:: 1725--1736.
23. Klinger MH, ((1997)) Platelets and inflammation. Anat Embryol (Berl) 196:: 1--11.
24. Schmitt-Sody M, Metz P, Gottschalk O, Zysk S, Birkenmaier C, et al. ((2007)) Selective inhibition of platelets by the GPIIb/IIIa receptor antagonist Tirofiban reduces leukocyte-endothelial cell interaction in murine antigen-induced arthritis. Inflamm Res 56:: 414--420.
25. Zago AC, Simon DI, Wang Y, Sakuma M, Chen Z, et al. ((2008)) The importance of the interaction between leukocyte integrin Mac-1 and platelet glycoprotein Ib-a for leukocyte recruitment by platelets and for the inflammatory response to vascular injury. Arq Bras Cardiol 90:: 54--63.
26. Wagner DD, Frenette PS, ((2008)) The vessel wall and its interactions. Blood 111:: 5271--5281.
27. Barrick CJ, Rojas M, Schoonhoven R, Smyth SS, Threadgill DW, ((2007)) Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy. Am J Physiol Heart Circ Physiol 292:: H2119--2130.
28. Hartley CJ, Reddy AK, Michael LH, Entman ML, Taffet GE, ((2009)) Coronary flow reserve as an index of cardiac function in mice with cardiovascular abnormalities. Conf Proc IEEE Eng Med Biol Soc 2009:: 1094--1097.
29. Hartley CJ, Reddy AK, Madala S, Michael LH, Entman ML, et al. ((2008)) Doppler estimation of reduced coronary flow reserve in mice with pressure overload cardiac hypertrophy. Ultrasound Med Biol 34:: 892--901.
30. Hartley CJ, Reddy AK, Madala S, Michael LH, Entman ML, et al. ((2007)) Effects of isoflurane on coronary blood flow velocity in young, old and ApoE(-/-) mice measured by Doppler ultrasound. Ultrasound Med Biol 33:: 512--521.
31. Livak KJ, Schmittgen TD, ((2001)) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:: 402--408.
32. Teekakirikul P, Eminaga S, Toka O, Alcalai R, Wang L, et al. ((2010)) Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-beta. J Clin Invest 120:: 3520--3529.
33. He K, Fu Y, Zhang W, Yuan J, Li Z, et al. ((2011)) Single-molecule imaging revealed enhanced dimerization of transforming growth factor beta type II receptors in hypertrophic cardiomyocytes. Biochem Biophys Res Commun 407:: 313--317.
34. Schultz Jel J, Witt SA, Glascock BJ, Nieman ML, Reiser PJ, et al. ((2002)) TGF-beta1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II. J Clin Invest 109:: 787--796.
35. Rosenkranz S, Flesch M, Amann K, Haeuseler C, Kilter H, et al. ((2002)) Alterations of beta-adrenergic signaling and cardiac hypertrophy in transgenic mice overexpressing TGF-beta(1). Am J Physiol Heart Circ Physiol 283:: H1253--1262.
36. von Hundelshausen P, Weber KS, Huo Y, Proudfoot AE, Nelson PJ, et al. ((2001)) RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium. Circulation 103:: 1772--1777.
37. Schafer A, Bauersachs J, ((2008)) Endothelial dysfunction, impaired endogenous platelet inhibition and platelet activation in diabetes and atherosclerosis. Curr Vasc Pharmacol 6:: 52--60.
38. Shoji T, Koyama H, Fukumoto S, Maeno T, Yokoyama H, et al. ((2006)) Platelet activation is associated with hypoadiponectinemia and carotid atherosclerosis. Atherosclerosis 188:: 190--195.
39. Cyrus T, Tang LX, Rokach J, FitzGerald GA, Pratico D, ((2001)) Lipid peroxidation and platelet activation in murine atherosclerosis. Circulation 104:: 1940--1945.
40. Nieswandt B, Bergmeier W, Rackebrandt K, Gessner JE, Zirngibl H, ((2000)) Identification of critical antigen-specific mechanisms in the development of immune thrombocytopenic purpura in mice. Blood 96:: 2520--2527.
41. Mombaerts P, Iacomini J, Johnson RS, Herrup K, Tonegawa S, et al. ((1992)) RAG-1-deficient mice have no mature B and T lymphocytes. Cell 68:: 869--877.
42. Hagihara M, Higuchi A, Tamura N, Ueda Y, Hirabayashi K, et al. ((2004)) Platelets, after exposure to a high shear stress, induce IL-10-producing, mature dendritic cells in vitro. J Immunol 172:: 5297--5303.
43. Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, et al. ((2007)) Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. J Am Coll Cardiol 49:: 2379--2393.
44. Stone PH, Coskun AU, Kinlay S, Clark ME, Sonka M, et al. ((2003)) Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up study. Circulation 108:: 438--444.
45. Harry BL, Sanders JM, Feaver RE, Lansey M, Deem TL, et al. ((2008)) Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 28:: 2003--2008.
46. Tzima E, Irani-Tehrani M, Kiosses WB, Dejana E, Schultz DA, et al. ((2005)) A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature 437:: 426--431.
47. Chen Z, Tzima E, ((2009)) PECAM-1 is necessary for flow-induced vascular remodeling. Arterioscler Thromb Vasc Biol 29:: 1067--1073.
48. Liu Y, Sweet DT, Irani-Tehrani M, Maeda N, Tzima E, ((2008)) Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation. J Cell Biol 182:: 185--196.
49. Goel R, Schrank BR, Arora S, Boylan B, Fleming B, et al. ((2008)) Site-specific effects of PECAM-1 on atherosclerosis in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol 28:: 1996--2002.
50. Elzey BD, Sprague DL, Ratliff TL, ((2005)) The emerging role of platelets in adaptive immunity. Cell Immunol 238:: 1--9.
51. Sowa JM, Crist SA, Ratliff TL, Elzey BD, ((2009)) Platelet influence on T- and B-cell responses. Arch Immunol Ther Exp (Warsz) 57:: 235--241.
52. Wang Y, Niu J, ((2008)) Platelets inhibit in vitro response of lymphocytes to mitogens. Immunol Lett 119:: 57--61.
53. Guzik TJ, Hoch NE, Brown KA, McCann LA, Rahman A, et al. ((2007)) Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction. J Exp Med 204:: 2449--2460.
54. Strom A, Wigren M, Hultgardh-Nilsson A, Saxena A, Gomez MF, et al. ((2007)) Involvement of the CD1d-natural killer T cell pathway in neointima formation after vascular injury. Circ Res 101:: e83--89.
55. Kvakan H, Kleinewietfeld M, Qadri F, Park JK, Fischer R, et al. ((2009)) Regulatory T cells ameliorate angiotensin II-induced cardiac damage. Circulation 119:: 2904--2912.
56. Cheng X, Liao YH, Ge H, Li B, Zhang J, et al. ((2005)) TH1/TH2 functional imbalance after acute myocardial infarction: coronary arterial inflammation or myocardial inflammation. J Clin Immunol 25:: 246--253.
57. Yu Q, Watson RR, Marchalonis JJ, Larson DF, ((2005)) A role for T lymphocytes in mediating cardiac diastolic function. Am J Physiol Heart Circ Physiol 289:: H643--651.
58. Yu Q, Horak K, Larson DF, ((2006)) Role of T lymphocytes in hypertension-induced cardiac extracellular matrix remodeling. Hypertension 48:: 98--104.
59. Schottelius AJ, Mayo MW, Sartor RB, Baldwin AS Jr, ((1999)) Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. J Biol Chem 274:: 31868--31874.
60. Mazighi M, Pelle A, Gonzalez W, Mtairag el M, Philippe M, et al. ((2004)) IL-10 inhibits vascular smooth muscle cell activation in vitro and in vivo. Am J Physiol Heart Circ Physiol 287:: H866--871.
61. Selzman CH, Meldrum DR, Cain BS, Meng X, Shames BD, et al. ((1998)) Interleukin-10 inhibits postinjury tumor necrosis factor-mediated human vascular smooth muscle proliferation. J Surg Res 80:: 352--356.
62. Krishnamurthy P, Rajasingh J, Lambers E, Qin G, Losordo DW, et al. ((2009)) IL-10 inhibits inflammation and attenuates left ventricular remodeling after myocardial infarction via activation of STAT3 and suppression of HuR. Circ Res 104:: e9--18.
63. Burchfield JS, Iwasaki M, Koyanagi M, Urbich C, Rosenthal N, et al. ((2008)) Interleukin-10 from transplanted bone marrow mononuclear cells contributes to cardiac protection after myocardial infarction. Circ Res 103:: 203--211.