Different in vitro toxicity of ribosome-inactivating proteins (RIPs) on sensory neurons and Schwann cells

Neuroscience Letters

Volumn 524, Issue 2, 2012, Pages 89-94

  Tong, Wai Man ^a   Sha, Ou ^a,b   Ng, Tzi Bun ^a   Cho, Eric Y P ^a   Kwong, Wing Hang ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b Shenzhen University   (China)

Author keywords

Neurotoxicity; Primary culture; Ribosome inactivating proteins; Ricin A chain; Ricinus communis agglutinin; Trichosanthin

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; AGGLUTININ; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; RIBOSOME INACTIVATING PROTEIN; RICIN A; RICINUS COMMUNIS AGGLUTININ; TRICHOSANTHIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; INTERNALIZATION; NEURITIS; NEUROTOXICITY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; SCHWANN CELL; SENSORY NERVE CELL; SIGNAL TRANSDUCTION;

EID: 84865170424     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.07.006     Document Type: Article

References (19)

1. Chan W.L., Shaw P.C., Tam S.C., Jacobsen C., Gliemann J., Nielsen M.S. Trichosanthin interacts with and enters cells via LDL receptor family members. Biochemical and Biophysical Research Communications 2000, 270:453-457.
2. Chow T.P., Feldman R.A., Lovett M., Piatak M. Isolation and DNA sequence of a gene encoding alpha-trichosanthin, a type I ribosome-inactivating protein. Journal of Biological Chemistry 1990, 265:8670-8674.
3. Endo Y., Mitsui K., Motizuki M., Tsurugi K. The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins. Journal of Biological Chemistry 1987, 262:5908-5912.
4. Fink D.J., Gainer H. Retrograde axonal transport of endogenous proteins in sciatic nerve demonstrated by covalent labeling in vivo. Science 1980, 208:303-305.
5. Frenoy J.P., Turpin E., Janicot M., Gehin-Fouque F., Desbuquois B. Uptake of injected 125I-ricin by rat liver in vivo. Subcellular distribution and characterization of the internalized ligand. Biochemical Journal 1992, 284:249-257.
6. Jirsova K., Sodaar P., Mandys V., Bar P.R. Cold jet: a method to obtain pure Schwann cell cultures without need for cytotoxic, apoptosis-inducing drug treatment. Journal of Neuroscience Methods 1997, 78:133-137.
7. Ling J., Liu W.Y., Wang T.P. Cleavage of supercoiled double-stranded DNA by several ribosome-inactivating proteins in vitro. FEBS Letters 1994, 345:143-146.
8. Maraganore J.M., Joseph M., Bailey M.C. Purification and characterization of tnichosanthin. Homology to the ricin A chain and implications as to mechanism of abortifacient activity. Journal of Biological Chemistry 1987, 262:11628-11633.
9. Moya M., Dautry-Varsat A., Goud B., Louvard D., Boquet P. Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin. Journal of Cell Biology 1985, 101:548-559.
10. Muramoto K., Kamiya H., Kawauchi H. The application of fluorescein isothiocyanate and high-performance liquid chromatography for the microsequencing of proteins and peptides. Analytical Biochemistry 1984, 141:446-450.
11. Roberts L.M., Smith D.C. Ricin: the endoplasmic reticulum connection. Toxicon 2004, 44:469-472.
12. Scarpini E., Kreider B.Q., Lisak R.P., Pleasure D.E. Establishment of Schwann cell cultures from adult rat peripheral nerves. Experimental Neurology 1988, 10:167-176.
13. Sha O., Kwong W.H., Cho Y.P.E., Yew T.W.D., Ng T.B. Different neuronal toxicity of single-chain ribosome-inactivating proteins on the rat retina. Toxicon 2008, 51:45-53.
14. Sha O., Yew D.T.W., Cho E.Y.P., Ng T.B., Yuan L., Kwong W.H. Mechanism of the specific neuronal toxicity of a type I ribosome-inactivating protein, trichosanthin. Neurotoxicology Research 2010, 18:161-172.
15. Shen W.Z., Sha O., Yew D.T.W., Kwong W.H. Retrograde transport of a traditional Chinese medicine, alpha-trichosanthin, and its selective neural toxicity. Clinical Toxicology (Phila) 2009, 47:876-883.
16. Thorpe P.E., Detre S.I., Foxwell B.M., Brown A.N., Skilleter D.N., Wilson G., Forrester J.A., Stirpe F. Modification of the carbohydrate in ricin with metaperiodate-cyanoborohydride mixtures. Effects on toxicity and in vivo distribution. European Journal of Biochemistry 1985, 147:197-206.
17. Villafranca J.E., Robertus J.D. Ricin B chain is a product of gene duplication. Journal of Biological Chemistry 1981, 256:554-556.
18. Wellner R.B., Pless D.D., Thompson W.L. Characterization of 3'-azido-3'-deoxythyrflidine inhibition of ricin and Pseudomonas exotoxin A toxicity in CHO and Veno cells. Journal of Cellular Physiology 1994, 159:495-505.
19. Wong K.B., Ke Y.B., Dong Y.C., Li X.B., Guo Y.W., Yeung H.W., Shaw P.C. Structure/function relationship study of G1n156, G1u160 and Glu189 in the active site of trichosanthin. European Journal of Biochemistry 1994, 221:787-791.