Twin-arginine translocase mutations that suppress folding quality control and permit export of misfolded substrate proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 33, 2012, Pages 13392-13397

  Rocco, Mark A ^a   Waraho Zhmayev, Dujduan ^a,b   DeLisa, Matthew P ^a  

^a Cornell University   (United States)

^b KING MONGKUT'S UNIVERSITY OF TECHNOLOGY THONBURI   (Thailand)

Author keywords

Library screening; Membrane protein; Protein folding; Protein translocation; Secretory pathway

Indexed keywords

ALKALINE PHOSPHATASE; ARGININE; BETA LACTAMASE TEM 1; CARRIER PROTEIN; EPITOPE; PROTEIN TAT A; PROTEIN TAT B; PROTEIN TAT C; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL TRANSLOCATION; ENZYME SPECIFICITY; MUTATION; NONHUMAN; PHOTOSYSTEM I; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN ISOLATION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TRANSPORT; QUALITY CONTROL; TWIN ARGININE TRANSLOCATION;

ALKALINE PHOSPHATASE; DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENES, SUPPRESSOR; MEMBRANE TRANSPORT PROTEINS; MUTANT PROTEINS; MUTATION; PROTEIN FOLDING; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; SELECTION, GENETIC; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; SUPPRESSION, GENETIC;

EID: 84865165273     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210140109     Document Type: Article

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