Flavonol glycosides from euphorbia microsciadia Bioss. with their Immunomodulatory Activities

Iranian Journal of Pharmaceutical Research

Volumn 11, Issue 3, 2012, Pages 925-930

  Ghanadian, Sayyed Mustafa ^a   Ayatollahi, Abdul Majid ^b   Afsharypour, Suleiman ^a   Hareem, Sumaira ^c   Abdalla, Omer Mohamed ^c   Bankeu, Jean Jules Kezetas ^d  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c UNIVERSITY OF KARACHI   (Pakistan)

^d UNIVERSITY OF YAOUNDÉ I   (Cameroon)

Author keywords

Euphorbia microsciadia; Flavonoids; Flavonol glycosides; Immunomodulatory activity

Indexed keywords

FLAVONOID GLYCOSIDE; HYDROXYL GROUP; IMMUNOMODULATING AGENT; MYRICETIN 3 O BETA D GALACTOPYRANOSIDE; PREDNISOLONE; QUERCETIN 3 O BETA D GALACTOPYRANOSIDE; QUERCETIN 3 O BETA D GLUCOPYRANOSIDE; QUERCETIN 3 O BETA D RUTINOSIDE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; EUPHORBIA; EUPHORBIA MICROSCIADIA; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; NUCLEAR MAGNETIC RESONANCE; T LYMPHOCYTE;

EID: 84865162655     PISSN: 17350328     EISSN: 17266890     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Karimi H. A Dictionary of Iran's Vegetation Plants. Parcham, Tehran (2002).
2. Amirghofran Z, Malek-hosseini S, Gholmoghaddam H and Kalalinia F. Inhibition of tumor cells growth and stimulation of lymphocytes by Euphorbia species. Immunopharmacol. Immunotoxicol. (2000) 1: 1-9.
3. Jassbi AR. Chemistry and biological activity of secondary metabolites in Euphorbia from Iran. Phytochem. (2006) 67: 1977-1984
4. Cushman M, Nagarathman D, Burg DL and Geahlen RL. Synthesis and proteintyrosine kinase inhibitory activities of flavonoid analogues. J. Med. Chem. (1991) 34: 798-806.
5. Ursini F, Maiorino M, Morazzoni P, Roveri A and Pifferi G. A novel antioxidant flavonoid (IdB 1031) affecting molecular mechanisms of cellular activation. Free Radic. Biol. Med. (1994) 16: 547-53.
6. Isakov N and Altman N. Human T lymphocyte activation by tumor promoters: role of protein kinase C. J. Immunol. (1987) 138: 3100-3107.
7. Ayatollahi AM, Ghanadian M, Mesaik MA, Omer MA, Afsharypuor S, Kobarfard F and Mirza-taheri M. New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity. J. Asian Nat. Prod. Res. (2010) 12: 1020-1025
8. Mabry T, Markham KR and Thomas MB. The Systematic Identification of Flavonoids. Springer, New York (1970).
9. Kumar N, Singh B, Bhandari P, Gupta AP, Uniyal SK and Kaul VK. Biflavonoids from Lonicera japonica. Phytochem. (2005) 66: 2740-2744.
10. Pegnyemb DE, Mbing JN, Théodore AA, Tih RG, Sondengam BL, Blond A and Bernard B. Antimicrobial biflavonoids from the aerial parts of Ouratea sulcata. Phytochem. (2005) 66: 1922-1926.
11. Foo LY, Lu Y, Molan AL, Woodfield DR and McNabb WC. The phenols and prodelphinidins of white clover flowers. Phytochem. (2000) 54: 539-548.
12. Chawla R, Arora R, Puri S. C, Sagar R. K, Singh S and Kumar R. 3-O-β-d-galactopyranoside of quercetin as an active principle from high altitude Podophyllum hexandrum and evaluation of its radioprotective properties. Z. Naturforsch. C (2005) 60: 728-738.
13. Deepralard K, Kawanishi K, Moriyasu M, PengsuparpT and Suttisri R. Flavonoid glycosides from the leaves of Uvaria rufa with advanced glycation end-products inhibitory activity. Thai. J. Pharm. Sci. (2009) 33: 84-90.
14. Shen G, Van Kiem P, Cai XF, Li G, Dat NT and Choi YA. Solanoflavone, a new biflavonol glycoside from Solanum melongena: seeking for anti-inflammatory components. Arch. Pharm. Res. (2005) 28: 657-659.
15. Dazzo FB, Yanke WE and Brill WJ. Trifolin: a Rhizobium recognition protein from white clover. Biochim. Biophys. Acta (1978) 539: 276-286.
16. 4(+)T cells in the antitumor immune response. J. Exp. Med. (1998) 188: 2357-2368.
17. Mishra B, Priyadarsini KI, Kumar MS, Unnikrishnan MK and Mohan H. Effect of O-glycosilation on the antioxidant activity and free radical reactions of a plant flavonoid, chrysoeriol. Bioorg. Med. Chem. (2003) 11: 2677-85.
18. You HJ, Ahn HJ and Ji GE. Transformation of rutin to antiproliferative quercetin-3-glucoside by Aspergillus niger. J. Agric. Food Chem. (2010) 58: 10886-10892.
19. Ayatollahi AM, Ghanadian M, Afsharypuor S, Mesaik MA, Abdella MO, Shahlaei M, Farzandi MG Cycloartanes from Euphorbia aellenii Rech. f. and their antiproliferative activity. Iranian J. Pharm. Res. (2011) 10: 105-112.