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Volumn 9, Issue 1, 2012, Pages

Beyond cell penetrating peptides: Designed molecular transporters

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ARGININE DERIVATIVE; CELL PENETRATING PEPTIDE; CYCLOSPORIN A; DENDRIMER; DOXYCYCLINE; GUANIDINE; NEOMYCIN;

EID: 84865162171     PISSN: None     EISSN: 17406749     Source Type: Journal    
DOI: 10.1016/j.ddtec.2011.07.004     Document Type: Review
Times cited : (48)

References (46)
  • 1
    • 39149103400 scopus 로고    scopus 로고
    • The design of guanidinium-rich transporters and their internalization mechanisms
    • Wender, P.A. et al. (2008) The design of guanidinium-rich transporters and their internalization mechanisms. Adv. Drug Deliv. Rev. 60, 452-472
    • (2008) Adv. Drug Deliv. Rev , vol.60 , pp. 452-472
    • Wender, P.A.1
  • 2
    • 0037428976 scopus 로고    scopus 로고
    • Arginine-containing peptides as delivery vectors
    • Tung, C.H. and Weissleder, R. (2003) Arginine-containing peptides as delivery vectors. Adv. Drug Deliv. Rev. 55, 281-294
    • (2003) Adv. Drug Deliv. Rev , vol.55 , pp. 281-294
    • Tung, C.H.1    Weissleder, R.2
  • 3
    • 0034700141 scopus 로고    scopus 로고
    • The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
    • Wender, P.A. et al. (2000) The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters. Proc. Natl. Acad. Sci. U.S.A. 97, 13003-13008
    • (2000) Proc. Natl. Acad. Sci. U.S.A , vol.97 , pp. 13003-13008
    • Wender, P.A.1
  • 4
    • 38949138457 scopus 로고    scopus 로고
    • Function oriented synthesis, step economy, and drug design
    • Wender, P.A. et al. (2008) Function oriented synthesis, step economy, and drug design. Acc. Chem. Res. 41, 40-49
    • (2008) Acc. Chem. Res , vol.41 , pp. 40-49
    • Wender, P.A.1
  • 5
    • 38949192863 scopus 로고    scopus 로고
    • Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers
    • DOI 10.1016/j.addr.2007.10.008, PII S0169409X0700289X
    • Torchilin, V.P. (2008) Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers. Adv. Drug Deliv. Rev. 60, 548-558 (Pubitemid 351215572)
    • (2008) Advanced Drug Delivery Reviews , vol.60 , Issue.4-5 , pp. 548-558
    • Torchilin, V.P.1
  • 6
    • 50449092432 scopus 로고    scopus 로고
    • Overcoming multidrug resistance of smallmolecule therapeutics through conjugation with releasable octaarginine transporters
    • Dubikovskaya, E.A. et al. (2008) Overcoming multidrug resistance of smallmolecule therapeutics through conjugation with releasable octaarginine transporters. Proc. Natl. Acad. Sci. 105, 12128-12133
    • (2008) Proc. Natl. Acad. Sci , vol.105 , pp. 12128-12133
    • Dubikovskaya, E.A.1
  • 8
    • 33646948225 scopus 로고    scopus 로고
    • Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation
    • DOI 10.1021/bc0503216
    • Goun, E.A. et al. (2006) Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation. Bioconjug. Chem. 17, 787-796 (Pubitemid 43794390)
    • (2006) Bioconjugate Chemistry , vol.17 , Issue.3 , pp. 787-796
    • Goun, E.A.1    Shinde, R.2    Dehnert, K.W.3    Adams-Bond, A.4    Wender, P.A.5    Contag, C.H.6    Franc, B.L.7
  • 10
    • 0033678653 scopus 로고    scopus 로고
    • Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation
    • Rothbard, J.B. et al. (2000) Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation. Nat. Med. 6, 1253-1257
    • (2000) Nat. Med , vol.6 , pp. 1253-1257
    • Rothbard, J.B.1
  • 11
    • 0024262589 scopus 로고
    • Cellular uptake of the tat protein from human immunodeficiency virus
    • DOI 10.1016/0092-8674(88)90263-2
    • Frankel, A.D. and Pabo, C.O. (1988) Cellular uptake of the Tat protein from human immunodeficiency virus. Cell 55, 1189-1193 (Pubitemid 19020071)
    • (1988) Cell , vol.55 , Issue.6 , pp. 1189-1193
    • Frankel, A.D.1    Pabo, C.O.2
  • 12
    • 0024209811 scopus 로고
    • Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein
    • DOI 10.1016/0092-8674(88)90262-0
    • Green, M. and Loewenstein, P.M. (1988) Autonomous functional domains of chemically synthesized human immunodeficiency virus tat transactivator domain. Cell 55, 1179-1188 (Pubitemid 19020070)
    • (1988) Cell , vol.55 , Issue.6 , pp. 1179-1188
    • Green, M.1    Loewenstein, P.M.2
  • 13
    • 0030904245 scopus 로고    scopus 로고
    • A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
    • Vive's, E. et al. (1997) A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272, 16010-16017
    • (1997) J. Biol. Chem , vol.272 , pp. 16010-16017
    • Vive's, E.1
  • 14
    • 0033794501 scopus 로고    scopus 로고
    • Polyarginine enters cells more efficiently than other cationic homopolymers
    • Mitchell, D.J. et al. (2000) Polyarginine enters cells more efficiently than other cationic homopolymers. J. Pept. Res. 56, 318-325
    • (2000) J. Pept. Res , vol.56 , pp. 318-325
    • Mitchell, D.J.1
  • 15
    • 3543051871 scopus 로고    scopus 로고
    • Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells
    • Rothbard, J.B. et al. (2004) Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells. J. Am. Chem. Soc. 126, 9506-9607
    • (2004) J. Am. Chem. Soc , vol.126 , pp. 9506-9607
    • Rothbard, J.B.1
  • 17
    • 0033520487 scopus 로고    scopus 로고
    • In vivo protein transduction: Delivery of a biologically active protein into the mouse
    • DOI 10.1126/science.285.5433.1569
    • Schwarze, S.R. et al. (1999) In vivo protein transduction: Delivery of a biologically active protein into the mouse. Science 285, 1569-1572 (Pubitemid 29420581)
    • (1999) Science , vol.285 , Issue.5433 , pp. 1569-1572
    • Schwarze, S.R.1    Ho, A.2    Vocero-Akbani, A.3    Dowdy, S.F.4
  • 18
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • Zhou, H. et al. (2009) Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4, 381-384
    • (2009) Cell Stem Cell , vol.4 , pp. 381-384
    • Zhou, H.1
  • 22
    • 0036523467 scopus 로고    scopus 로고
    • Cellular uptake studies with Beta-peptides
    • Rueping, M. et al. (2002) Cellular uptake studies with Beta-peptides. Chembiochem 3, 257-259
    • (2002) Chembiochem , vol.3 , pp. 257-259
    • Rueping, M.1
  • 23
    • 0037073171 scopus 로고    scopus 로고
    • Oligocarbamate molecular transporters: Design, synthesis, and biological evaluation of a new class of transporters for drug delivery
    • DOI 10.1021/ja0275109
    • Wender, P.A. et al. (2002) Oligocarbamate molecular transporters: Design, synthesis, and biological evaluation of a new class of transporters for drug delivery. J. Am. Chem. Soc. 124, 13382-13383 (Pubitemid 35285905)
    • (2002) Journal of the American Chemical Society , vol.124 , Issue.45 , pp. 13382-13383
    • Wender, P.A.1    Rothbard, J.B.2    Jessop, T.C.3    Kreider, E.L.4    Wylie, B.L.5
  • 26
    • 0037172801 scopus 로고    scopus 로고
    • Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membrane-permeable peptides
    • DOI 10.1021/bi0256173
    • Futaki, S. et al. (2002) Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membrane-permeable peptides. Biochemistry 41, 7925-7930 (Pubitemid 34655157)
    • (2002) Biochemistry , vol.41 , Issue.25 , pp. 7925-7930
    • Futaki, S.1    Nakase, I.2    Suzuki, T.3    Youjun, Z.4    Sugiura, Y.5
  • 27
    • 1542406433 scopus 로고    scopus 로고
    • Dendritic oligoguanidines as intracellular translocators
    • Chung, H.H. et al. (2004) Dendritic oligoguanidines as intracellular translocators. Biopolym. - Pept. Sci. 76, 83-96
    • (2004) Biopolym Pept. Sci , vol.76 , pp. 83-96
    • Chung, H.H.1
  • 28
    • 33947661931 scopus 로고    scopus 로고
    • Dendritic molecular transporters provide control of delivery to intracellular compartments
    • DOI 10.1021/bc060287a
    • Huang, K. et al. (2007) Dendritic molecular transporters provide control of delivery to intracellular compartments. Bioconjug. Chem. 18, 403-409 (Pubitemid 46493511)
    • (2007) Bioconjugate Chemistry , vol.18 , Issue.2 , pp. 403-409
    • Huang, K.1    Voss, B.2    Kumar, D.3    Hamm, H.E.4    Harth, E.5
  • 29
    • 27644470173 scopus 로고    scopus 로고
    • Dendrimeric molecular transporters: Synthesis and evaluation of tunable polyguanidino dendrimers that facilitate cellular uptake
    • DOI 10.1021/ol051496y
    • Wender, P.A. et al. (2005) Dendritic molecular transporters: Synthesis and evaluation of tunable polyguanidino dendrimers that facilitate cellular uptake. Org. Lett. 7, 4815-4818 (Pubitemid 41579870)
    • (2005) Organic Letters , vol.7 , Issue.22 , pp. 4815-4818
    • Wender, P.A.1    Kreider, E.2    Pelkey, E.T.3    Rothbard, J.4    VanDeusen, C.L.5
  • 32
    • 33645775235 scopus 로고    scopus 로고
    • Impact of the guanidinium group on hybridization and cellular uptake of cationic oligonucleotides
    • Deglane, G. et al. (2006) Impact of the guanidinium group on hybridization and cellular uptake of cationic oligonucleotides. Chembiochem 7, 684-692
    • (2006) Chembiochem , vol.7 , pp. 684-692
    • Deglane, G.1
  • 33
    • 0028059256 scopus 로고
    • Design and synthesis of deoxynucleic guanidine: A polycation analogue of DNA
    • Dempcy, O.R. et al. (1994) Design and synthesis of deoxynucleic guanidine: A polycation analogue of DNA. Proc. Natl. Acad. Sci. U.S.A. 91, 7864-7868
    • (1994) Proc. Natl. Acad. Sci. U.S.A , vol.91 , pp. 7864-7868
    • Dempcy, O.R.1
  • 34
    • 0034614052 scopus 로고    scopus 로고
    • Guanidinoglycosides: A novel family of RNA ligands
    • Luedtke, N.W. et al. (2000) Guanidinoglycosides: A novel family of RNA ligands. J. Am. Chem. Soc. 122, 12035-12036
    • (2000) J. Am. Chem. Soc , vol.122 , pp. 12035-12036
    • Luedtke, N.W.1
  • 35
    • 0141954275 scopus 로고    scopus 로고
    • Cellular uptake of aminoglycosides, guanidinoglycosides, and poly-arginine
    • DOI 10.1021/ja0360135
    • Luedtke, N.W. et al. (2003) Cellular uptake of aminoglycosides, guanidinoglycosides, and poly-arginine. J.Am.Chem. Soc. 125, 12374-12375 (Pubitemid 37254733)
    • (2003) Journal of the American Chemical Society , vol.125 , Issue.41 , pp. 12374-12375
    • Luedtke, N.W.1    Carmichael, P.2    Tor, Y.3
  • 39
    • 33846442406 scopus 로고    scopus 로고
    • Design, synthesis, and delivery properties of novel guanidine-containing molecular transporters built on dimeric inositol scaffolds
    • DOI 10.1002/chem.200600898
    • Maiti, K.K. et al. (2007) Design, synthesis, and delivery properties of novel guanidine-containing molecular transporters built on dimeric inositol scaffolds. Chem. Eur. J. 13, 762-775 (Pubitemid 46144553)
    • (2007) Chemistry - A European Journal , vol.13 , Issue.3 , pp. 762-775
    • Maiti, K.K.1    Jeon, O.-Y.2    Lee, W.S.3    Chung, S.-K.4
  • 41
    • 0035909603 scopus 로고    scopus 로고
    • An efficient, scalable synthesis of the molecular transporter octaarginine via a segment doubling strategy
    • DOI 10.1021/ol0161108
    • Wender, P.A. et al. (2001) An efficient, scalable synthesis of the molecular transporter octaarginine via a segment doubling strategy. Org. Lett. 3, 3229-3232 (Pubitemid 33625328)
    • (2001) Organic Letters , vol.3 , Issue.21 , pp. 3229-3232
    • Wender, P.A.1    Jessop, T.C.2    Pattabiraman, K.3    Pelkey, E.T.4    VanDeusen, C.L.5
  • 42
    • 42649099978 scopus 로고    scopus 로고
    • A polymeric domain that promotes cellular internalization
    • DOI 10.1021/ja8001716
    • Kolonko, E.M. and Kiessling, L.L. (2008) A polymeric domain that promotes cellular internalization. J. Am. Chem. Soc. 130, 5626-5627 (Pubitemid 351600476)
    • (2008) Journal of the American Chemical Society , vol.130 , Issue.17 , pp. 5626-5627
    • Kolonko, E.M.1    Kiessling, L.L.2
  • 43
    • 67650292734 scopus 로고    scopus 로고
    • General synthetic route to cell-permeable block copolymers via ROMP
    • Kolonko, E.M. et al. (2009) General synthetic route to cell-permeable block copolymers via ROMP. J. Am. Chem. Soc. 131, 7327-7333
    • (2009) J. Am. Chem. Soc , vol.131 , pp. 7327-7333
    • Kolonko, E.M.1
  • 44
    • 48749112671 scopus 로고    scopus 로고
    • Stimuli-responsive polyguanidinooxanorbornene membrane transporters as multicomponent sensors in complex matrices
    • Henning, A. et al. (2008) Stimuli-responsive polyguanidinooxanorbornene membrane transporters as multicomponent sensors in complex matrices. J. Am. Chem. Soc. 130, 10338-10344
    • (2008) J. Am. Chem. Soc , vol.130 , pp. 10338-10344
    • Henning, A.1
  • 45
    • 57049118019 scopus 로고    scopus 로고
    • Synthetic mimic of antimicrobial peptide with nonmembrane-disrupting antibacterial properties
    • Gabriel, G.J. et al. (2008) Synthetic mimic of antimicrobial peptide with nonmembrane-disrupting antibacterial properties. Biomacromolecules 9, 2980-2983
    • (2008) Biomacromolecules , vol.9 , pp. 2980-2983
    • Gabriel, G.J.1
  • 46
    • 70450169425 scopus 로고    scopus 로고
    • Oligocarbonate molecular transporters: Oligomerization-based syntheses and cell-penetrating studies
    • Cooley, C.B. et al. (2009) Oligocarbonate molecular transporters: Oligomerization-based syntheses and cell-penetrating studies. J. Am. Chem. Soc. 131, 16401-16403
    • (2009) J. Am. Chem. Soc , vol.131 , pp. 16401-16403
    • Cooley, C.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.