Caffeine relaxes smooth muscle through actin depolymerization

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 303, Issue 4, 2012, Pages

  Tazzeo, Tracy ^a   Bates, Genevieve ^b   Roman, Horia Nicolae ^b   Lauzon, Anne Marie ^b   Khasnis, Mukta D ^c   Eto, Masumi ^c   Janssen, Luke J ^a  

^a ST JOSEPH S HOSPITAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Airway smooth muscle; Asthma; Ca 2+ handling; Excitation contraction coupling; Ryanodine

Indexed keywords

ACTIN; BETA ESCIN; CAFFEINE; CALCIUM ION; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN KINASE; PHOSPHODIESTERASE IV; PROTEIN KINASE C; QUININE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHODILATATION; DEPOLYMERIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE;

ACTINS; ANIMALS; BIOPOLYMERS; CAFFEINE; CATTLE; ENZYME ASSAYS; HUMANS; INDOLES; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH; MYOSIN-LIGHT-CHAIN KINASE; PERMEABILITY; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; POLYMERIZATION; POTASSIUM CHLORIDE; THEOPHYLLINE;

EID: 84865153428     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00103.2012     Document Type: Article

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