Ischemic pre-and postconditioning has pronounced effects on gene expression profiles in the rat liver after ischemia/reperfusion

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 303, Issue 4, 2012, Pages

  Knudsen, Anders Riegels ^a   Kannerup, Anne Sofie ^a   Dich, Rune ^a   Funch Jensen, Peter ^a   Gronbæk, Henning ^a   Kruhoffer, Mogens ^b   Mortensen, Frank Viborg ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AROS Applied Biotechnology   (Denmark)

Author keywords

Ischemia reperfusion injuries; Liver failure; Microarray analysis

Indexed keywords

COMPLEMENTARY DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CELL GROWTH; CELL PROLIFERATION; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE NUMBER; HOMEOSTASIS; ISCHEMIC POSTCONDITIONING; ISCHEMIC PRECONDITIONING; LIVER BIOPSY; LIVER ISCHEMIA; LIVER PROTECTION; MALE; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; BIOLOGICAL MARKERS; BIOPSY; CLUSTER ANALYSIS; DATABASES, GENETIC; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; ISCHEMIC POSTCONDITIONING; ISCHEMIC PRECONDITIONING; LIVER; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS;

EID: 84865153156     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00337.2011     Document Type: Article

References (38)

1. Brown JR, Nigh E, Lee RJ, Ye H, Thompson MA, Saudou F, Pestell RG, Greenberg ME. Fos family members induce cell cycle entry by activating cyclin D1. Mol Cell Biol 18: 5609-5619, 1998.
2. Carmel JB, Kakinohana O, Mestril R, Young W, Marsala M, Hart RP. Mediators of ischemic preconditioning identified by microarray anal-ysis of rat spinal cord. Exp Neurol 185: 81-96, 2004.
3. Clavien PA, Selzner M, Rudiger HA, Graf R, Kadry Z, Rousson V, Jochum W. A prospective randomized study in 100 consecutive patients undergoing major liver resection with versus without ischemic preconditioning. Ann Surg 238: 843-850, 2003.
4. Das M, Das DK. Molecular mechanism of preconditioning. IUBMB Life 60: 199-203, 2008.
5. de RO, Lehmann K, Clavien PA. Preconditioning, organ preservation, and postconditioning to prevent ischemia-reperfusion injury to the liver. Liver Transpl 15: 1172-1182, 2009.
6. Dennis G Jr, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, Lempicki RA. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol 4: 3, 2003.
7. Glanemann M, Vollmar B, Nussler AK, Schaefer T, Neuhaus P, Menger MD. Ischemic preconditioning protects from hepatic ischemia/reperfusion-injury by preservation of microcirculation and mitochondrial redox-state. J Hepatol 38: 59-66, 2003.
8. Granfeldt A, Lefer DJ, Vinten-Johansen J. Protective ischaemia in patients: preconditioning and postconditioning. Cardiovasc Res 83: 234-246, 2009.
9. Halkos ME, Kerendi F, Corvera JS, Wang NP, Kin H, Payne CS, Sun HY, Guyton RA, Vinten-Johansen J, Zhao ZQ. Myocardial protection with postconditioning is not enhanced by ischemic preconditioning. Ann Thorac Surg 78: 961-969, 2004.
10. Hess J, Angel P, Schorpp-Kistner M. AP-1 subunits: quarrel and harmony among siblings. J Cell Sci 117: 5965-5973, 2004.
11. Huang dW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57, 2009.
12. Huang J, Qi R, Quackenbush J, Dauway E, Lazaridis E, Yeatman T. Effects of ischemia on gene expression. J Surg Res 99: 222-227, 2001.
13. Jaeschke H. Mechanisms of liver injury. II. Mechanisms during hepatic ischemia-reperfusion and other acute inflammatory conditions. Am J Physiol Gastrointest Liver Physiol 290: G1083-G1088, 2006.
14. Jaeschke H. Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Am J Physiol Gastrointest Liver Physiol 284: G15-G26, 2003.
15. Jassem W, Fuggle S, Thompson R, Arno M, Taylor J, Byrne J, Heaton N, Rela M. Effect of ischemic preconditioning on the genomic response to reperfusion injury in deceased donor liver transplantation. Liver Transpl 15: 1750-1765, 2009.
16. Knudsen AR, Kannerup AS, Dich R, Kruhoffer M, Funch-Jensen P, Gronbaek H, Mortensen FV. Expression of genes involved in rat liver angiogenesis after ischaemia and reperfusion: effects of ischaemic pre-and post-conditioning. HPB (Oxford) 12: 554-560, 2010.
17. Knudsen AR, Kannerup AS, Gronbaek H, Andersen KJ, Funch-Jensen P, Frystyk J, Flyvbjerg A, Mortensen FV. Effects of ischemic pre-and postconditioning on HIF-1alpha, VEGF and TGF-beta expression after warm ischemia and reperfusion in the rat liver. Comp Hepatol 10: 3, 2011.
18. Knudsen AR, Kannerup AS, Gronbaek H, Dutoit SH, Nyengaard JR, Funch-Jensen P, Mortensen FV. Quantitative histological assessment of hepatic ischemia-reperfusion injuries following ischemic pre-and postconditioning in the rat liver. J Surg Res 2012 Apr 11 [Epub ahead of print].
19. Konstantinov IE, Arab S, Kharbanda RK, Li J, Cheung MM, Cherepanov V, Downey GP, Liu PP, Cukerman E, Coles JG, Redington AN. The remote ischemic preconditioning stimulus modifies inflammatory gene expression in humans. Physiol Genomics 19: 143-150, 2004.
20. Konstantinov IE, Arab S, Li J, Coles JG, Boscarino C, Mori A, Cukerman E, Dawood F, Cheung MM, Shimizu M, Liu PP, Redington AN. The remote ischemic preconditioning stimulus modifies gene expression in mouse myocardium. J Thorac Cardiovasc Surg 130: 1326-1332, 2005.
21. Koti RS, Seifalian AM, Davidson BR. Protection of the liver by ischemic preconditioning: a review of mechanisms and clinical applications. Dig Surg 20: 383-396, 2003.
22. Matsuyama N, Leavens JE, McKinnon D, Gaudette GR, Aksehirli TO, Krukenkamp IB. Ischemic but not pharmacological preconditioning requires protein synthesis. Circulation 102: III 312-318, 2000.
23. Moore-Olufemi SD, Olufemi SE, Lott S, Sato N, Kozar RA, Moore FA, Radhakrishnan RS, Shah S, Jimenez F, Kone BC, Cox CS Jr. Intestinal ischemic preconditioning after ischemia/reperfusion injury in rat intestine: profiling global gene expression patterns. Dig Dis Sci 55: 1866-1877, 2009.
24. Navarro-Sabate A, Peralta C, Calvo MN, Manzano A, Massip-Salcedo M, Rosello-Catafau J, Bartrons R. Mediators of rat ischemic hepatic preconditioning after cold preservation identified by microarray analysis. Liver Transpl 12: 1615-1625, 2006.
25. Nitta-Komatsubara Y, Abe K, Aoki M, Isoyama S. Altered ischemic induction of immediate early gene and heat shock protein 70 mRNAs after preconditioning in rat hearts. Life Sci 66: 1261-1270, 2000.
26. Peralta C, Hotter G, Closa D, Prats N, Xaus C, Gelpi E, Rosello-Catafau J. The protective role of adenosine in inducing nitric oxide synthesis in rat liver ischemia preconditioning is mediated by activation of adenosine A2 receptors. Hepatology 29: 126-132, 1999.
27. Rudiger HA, Graf R, Clavien PA. Sub-lethal oxidative stress triggers the protective effects of ischemic preconditioning in the mouse liver. J Hepatol 39: 972-977, 2003.
28. Saeed AI, Sharov V, White J, Li J, Liang W, Bhagabati N, Braisted J, Klapa M, Currier T, Thiagarajan M, Sturn A, Snuffin M, Rezantsev A, Popov D, Ryltsov A, Kostukovich E, Borisovsky I, Liu Z, Vinsavich A, Trush V, Quackenbush J. TM4: a free, open-source system for microarray data management and analysis. Biotechniques 34: 374-378, 2003.
29. Schlossberg H, Zhang Y, Dudus L, Engelhardt JF. Expression of c-fos and c-jun during hepatocellular remodeling following ischemia/reperfusion in mouse liver. Hepatology 23: 1546-1555, 1996.
30. Schmidt E, Schmidt FW. Enzyme diagnosis of liver diseases. Clin Biochem 26: 241-251, 1993.
31. Simkhovich BZ, Marjoram P, Poizat C, Kedes L, Kloner RA. Brief episode of ischemia activates protective genetic program in rat heart: a gene chip study. Cardiovasc Res 59: 450-459, 2003.
32. Sun K, Liu ZS, Sun Q. Role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning. World J Gastroenterol 10: 1934-1938, 2004.
33. Teoh N, Dela Pena A, Farrell G. Hepatic ischemic preconditioning in mice is associated with activation of NF-kappaB, p38 kinase, and cell cycle entry. Hepatology 36: 94-102, 2002.
34. Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98: 5116-5121, 2001.
35. van der Bilt JD, Livestro DP, Borren A, van HR, Borel RI. European survey on the application of vascular clamping in liver surgery. Dig Surg 24: 423-435, 2007.
36. Wang KX, Hu SY, Jiang XS, Zhu M, Jin B, Zhang GY, Chen B. Protective effects of ischaemic postconditioning on warm/cold ischaemic reperfusion injury in rat liver: a comparative study with ischaemic preconditioning. Chin Med J (Engl) 121: 2004-2009, 2008.
37. Wu BQ, Chu WW, Zhang LY, Wang P, Ma QY, Wang DH. Protection of preconditioning, postconditioning and combined therapy against hepatic ischemia/reperfusion injury. Chin J Traumatol 10: 223-227, 2007.
38. Xi J, McIntosh R, Shen X, Lee S, Chanoit G, Criswell H, Zvara DA, Xu Z. Adenosine A2A and A2B receptors work in concert to induce a strong protection against reperfusion injury in rat hearts. J Mol Cell Cardiol 47: 684-690, 2009.