Development of stable HSPA1A promoter-driven luciferase reporter HepG2 cells for assessing the toxicity of organic pollutants present in air

Cell Stress and Chaperones

Volumn 17, Issue 5, 2012, Pages 567-576

  Xin, Lili ^a   Li, Xiaohai ^a   Deng, Huaxin ^a   Kuang, Dan ^a   Dai, Xiayun ^a   Huang, Suli ^a   Wang, Feng ^b   He, Meian ^a   Currie, R William ^c   Wu, Tangchun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Cell viability; Cellular damage; HSPA1A promoter activity; Luciferase reporter; Organic pollutants; Toxicity assessment

Indexed keywords

BENZO[A]PYRENE; FORMALDEHYDE; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN A1A; LUCIFERASE; MALONALDEHYDE; PYRENE; UNCLASSIFIED DRUG;

AIR POLLUTANT; AIR SAMPLING; AMBIENT AIR; ARTICLE; CELL DAMAGE; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; GENE; GENETIC TRANSFECTION; HEAT SHOCK; HSPA1A GENE; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; TOXICITY TESTING;

AIR POLLUTANTS; BENZO(A)PYRENE; CELL SURVIVAL; FORMALDEHYDE; GENES, REPORTER; HEP G2 CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LUCIFERASES; MALONDIALDEHYDE; PROMOTER REGIONS, GENETIC; PYRENES;

EID: 84865150278     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-012-0332-8     Document Type: Article

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