New highly sensitive rodent and human tests for soluble amyloid precursor protein alpha quantification: Preclinical and clinical applications in Alzheimer's disease

BMC Neuroscience

Volumn 13, Issue 1, 2012, Pages

  Rose, Christiane ^a   Peoc'h, Katell ^b,c   Chasseigneaux, Stéphanie ^a,b,c   Paquet, Claire ^b,d   Dumurgier, Julien ^b   Bourasset, Fanchon ^b   Calon, Frédéric ^e   Laplanche, Jean Louis ^b   Hugon, Jacques ^b,d   Allinquant, Bernadette ^a  

^a INSERM   (France)

^b HÔPITAL LARIBOISIÈRE   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d INSTITUT DU FER À MOULIN   (France)

^e UNIVERSITÉ LAVAL   (Canada)

Author keywords

Alzheimer's disease; Cerebrospinal fluid; Homogeneous time resolved fluorescence; Human; Primary neurons; Rodent; Sensitivity; Soluble amyloid precursor protein alpha

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CEREBROSPINAL FLUID ANALYSIS; CULTURE MEDIUM; DISEASE COURSE; FLUORESCENCE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IN VIVO STUDY; LABORATORY TEST; MOUSE; NERVE CELL CULTURE; NONHUMAN; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; RODENT; SENSITIVITY ANALYSIS; WILD TYPE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; HUMANS; LINEAR MODELS; MICE; MICE, TRANSGENIC; NEUROBLASTOMA; NEURONS; PEPTIDE FRAGMENTS; PRESENILIN-1; SPINAL PUNCTURE; TAU PROTEINS; TIME FACTORS;

EID: 84865145017     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-13-84     Document Type: Article

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