Immunofluorescent localization of the Rab-GAP protein TBC1D4 (AS160) in mouse kidney

Histochemistry and Cell Biology

Volumn 138, Issue 1, 2012, Pages 101-112

  Lier, Natascha ^a   Gresko, Nikolay ^a   Di Chiara, Marianna ^a   Loffing Cueni, Dominique ^a   Loffing, Johannes ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Amiloride; Distal tubule; Rab proteins; Thiazide; Transport

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANTIBODY; EPITHELIAL SODIUM CHANNEL; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; TBC1D4 ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BOWMAN CAPSULE; CELL MIGRATION; CONTROLLED STUDY; EPITHELIUM CELL; HENLE LOOP; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; KIDNEY COLLECTING TUBULE; KIDNEY DISTAL TUBULE; KIDNEY HOMOGENATE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ANIMALS; FLUORESCENT ANTIBODY TECHNIQUE; GTPASE-ACTIVATING PROTEINS; KIDNEY; KIDNEY TUBULES, DISTAL; LOOP OF HENLE; MICE; MICE, INBRED STRAINS;

MUS; ORYCTOLAGUS CUNICULUS;

EID: 84865121408     PISSN: 09486143     EISSN: 1432119X     Source Type: Journal    
DOI: 10.1007/s00418-012-0944-1     Document Type: Article

References (61)

1. Albiston AL, Yeatman HR, Pham V, Fuller SJ, Diwakarla S, Fernando RN, Chai SY (2011) Distinct distribution of GLUT4 and insulin regulated aminopeptidase in the mouse kidney. Regul Pept 166:83-89
2. Alves DS, Farr GA, Seo-Mayer P, Caplan MJ (2010) AS160 associates with the Na?, K?-ATPase and mediates the adenosine monophosphate- stimulated protein kinase-dependent regulation of sodium pump surface expression. Mol Biol Cell 21:4400-4408
3. Barr F, Lambright DG (2010) Rab GEFs and GAPs. Curr Opin Cell Biol 22:461-470
4. Baus D, Heermeier K, De Hoop M, Metz-Weidmann C, Gassenhuber J, Dittrich W, Welte S, Tennagels N (2008) Identification of a novel AS160 splice variant that regulates GLUT4 translocation and glucose-uptake in rat muscle cells. Cell Signal 20:2237-2246
5. Brosius FC 3rd, Briggs JP, Marcus RG, Barac-Nieto M, Charron MJ (1992) Insulin-responsive glucose transporter expression in renal microvessels and glomeruli. Kidney Int 42:1086-1092
6. Brown D, Lydon J, McLaughlin M, Stuart-Tilley A, Tyszkowski R, Alper S (1996) Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS). Histochem Cell Biol 105:261-267 (Pubitemid 26113171)
7. Busque SM, Wagner CA (2009) Potassium restriction, high protein intake, and metabolic acidosis increase expression of the glutamine transporter SNAT3 (Slc38a3) in mouse kidney. Am J Physiol Renal Physiol 297:F440-F450
8. Butlen D, Vadrot S, Roseau S, Morel F (1988) Insulin receptors along the rat nephron: 125I insulin binding in microdissected glomeruli and tubules. Pflugers Arch 412:604-612
9. Chabardes-Garonne D, Mejean A, Aude JC, Cheval L, Di Stefano A, Gaillard MC, Imbert-Teboul M, Wittner M, Balian C, Anthouard V, Robert C, Segurens B, Wincker P, Weissenbach J, Doucet A, Elalouf JM (2003) A panoramic view of gene expression in the human kidney. Proc Natl Acad Sci USA 100:13710-13715 (Pubitemid 37444804)
10. Chen S, Wasserman DH, MacKintosh C, Sakamoto K (2011) Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking. Cell Metab 13:68-79
11. Chin E, Zhou J, Bondy C (1993) Anatomical and developmental patterns of facilitative glucose transporter gene expression in the rat kidney. J Clin Invest 91:1810-1815 (Pubitemid 23127388)
12. Comellas AP, Kelly AM, Trejo HE, Briva A, Lee J, Sznajder JI, Dada LA (2010) Insulin regulates alveolar epithelial function by inducing Na?/K?-ATPase translocation to the plasma membrane in a process mediated by the action of Akt. J Cell Sci 123:1343-1351
13. Dash S, Sano H, Rochford JJ, Semple RK, Yeo G, Hyden CS, Soos MA, Clark J, Rodin A, Langenberg C, Druet C, Fawcett KA, Tung YC, Wareham NJ, Barroso I, Lienhard GE, O'Rahilly S, Savage DB (2009) A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia. Proc Natl Acad Sci USA 106:9350-9355
14. Eguez L, Lee A, Chavez JA, Miinea CP, Kane S, Lienhard GE, McGraw TE (2005) Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein. Cell Metab 2:263-272
15. Feraille E, Doucet A (2001) Sodium-potassium-adenosinetriphosphatase- dependent sodium transport in the kidney: hormonal control. Physiol Rev 81:345-418 (Pubitemid 32096179)
16. Frasa MA, Koessmeier KT, Ahmadian MR, Braga VM (2012) Illuminating the functional and structural repertoire of human TBC/RABGAPs. Nat Rev Mol Cell Biol 13:67-73
17. Guder WG, Ross BD (1984) Enzyme distribution along the nephron. Kidney Int 26:101-111 (Pubitemid 14017047)
18. Heilig C, Zaloga C, Lee M, Zhao X, Riser B, Brosius F, Cortes P (1995) Immunogold localization of high-affinity glucose transporter isoforms in normal rat kidney. Lab Invest 73:674-684
19. Hemken P, Guo XL, Wang ZQ, Zhang K, Gluck S (1992) Immunologic evidence that vacuolar H? ATPases with heterogeneous forms of Mr = 31,000 subunit have different membrane distributions in mammalian kidney. J Biol Chem 267:9948-9957
20. Ishikura S, Bilan PJ, Klip A (2007) Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells. Biochem Biophys Res Commun 353:1074-1079 (Pubitemid 46080408)
21. Jung HJ, Kwon TH (2010) Membrane trafficking of collecting duct water channel protein AQP2 regulated by Akt/AS160. Electrolyte Blood Press 8:59-65
22. Kane S, Sano H, Liu SC, Asara JM, Lane WS, Garner CC, Lienhard GE (2002) A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPaseactivating protein (GAP) domain. J Biol Chem 277:22115-22118 (Pubitemid 34967174)
23. Karlsson HK, Zierath JR, Kane S, Krook A, Lienhard GE, Wallberg- Henriksson H (2005) Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects. Diabetes 54:1692-1697 (Pubitemid 40770759)
24. Kim J, Kim YH, Cha JH, Tisher CC, Madsen KM (1999) Intercalated cell subtypes in connecting tubule and cortical collecting duct of rat and mouse. J Am Soc Nephrol 10:1-12 (Pubitemid 29034936)
25. Kim HY, Choi HJ, Lim JS, Park EJ, Jung HJ, Lee YJ, Kim SY, Kwon TH (2011) Emerging role of Akt substrate protein AS160 in the regulation of AQP2 translocation. Am J Physiol Renal Physiol 301:F151-F161
26. Kishore BK, Mandon B, Oza NB, DiGiovanni SR, Coleman RA, Ostrowski NL, Wade JB, Knepper MA (1996) Rat renal arcade segment expresses vasopressin-regulated water channel and vasopressin V2 receptor. J Clin Invest 97:2763-2771 (Pubitemid 26197716)
27. Kriz W, Kaissling B (2008) Structural organization of the mammalian kidney. In: Alpern RJ, Hebert SC (eds) Seldin and Giebisch's The Kidney Physiology and Pathophysiology, vol 1, Academic PressBurlington, San Diego, pp 479-564
28. Larance M, Ramm G, Stockli J, van Dam EM, Winata S, Wasinger V, Simpson F, Graham M, Junutula JR, Guilhaus M, James DE (2005) Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking. J Biol Chem 280:37803-37813 (Pubitemid 41642391)
29. Liang X, Butterworth MB, Peters KW, Frizzell RA (2010) AS160 modulates aldosterone-stimulated epithelial sodium channel forward trafficking. Mol Biol Cell 21:2024-2033
30. Lim YS, Chua CE, Tang BL (2011) Rabs and other small GTPases in ciliary transport. Biol Cell 103:209-221
31. Loffing J, Kaissling B (2003) Sodium and calcium transport pathways along the mammalian distal nephron: from rabbit to human. Am J Physiol Renal Physiol 284:F628-F643 (Pubitemid 36336969)
32. Loffing J, Korbmacher C (2009) Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC). Pflugers Arch 458:111-135
33. Loffing J, Pietri L, Aregger F, Bloch-Faure M, Ziegler U, Meneton P, Rossier BC, Kaissling B (2000) Differential subcellular localization of ENaC subunits in mouse kidney in response to highand low-Na diets. Am J Physiol Renal Physiol 279:F252-F258
34. Loffing J, Loffing-Cueni D, Valderrabano V, Klausli L, Hebert SC, Rossier BC, Hoenderop JG, Bindels RJ, Kaissling B (2001) Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron. Am J Physiol Renal Physiol 281:F1021-F1027
35. Loffing J, Vallon V, Loffing-Cueni D, Aregger F, Richter K, Pietri L, Bloch-Faure M, Hoenderop JG, Shull GE, Meneton P, Kaissling B (2004) Altered renal distal tubule structure and renal Na(?) and Ca(2?) handling in a mouse model for Gitelman's syndrome. J Am Soc Nephrol 15:2276-2288 (Pubitemid 39159328)
36. Mandon B, Nielsen S, Kishore BK, Knepper MA (1997) Expression of syntaxins in rat kidney. Am J Physiol 273:F718-F730 (Pubitemid 27508367)
37. Mather A, Pollock C (2011) Glucose handling by the kidney. Kidney Int Suppl:S1-6
38. Mendes AI, Matos P, Moniz S, Jordan P (2010) Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex. J Biol Chem 285:39117- 39126
39. Miinea CP, Sano H, Kane S, Sano E, Fukuda M, Peranen J, Lane WS, Lienhard GE (2005) AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain. Biochem J 391:87-93 (Pubitemid 41445479)
40. Mount DB (2006) Membrane trafficking and the regulation of NKCC2. Am J Physiol Renal Physiol 290:F606-F607 (Pubitemid 43724960)
41. Murer H, Hernando N, Forster I, Biber J (2003) Regulation of Na/Pi transporter in the proximal tubule. Annu Rev Physiol 65:531- 542 (Pubitemid 38249166)
42. Mutig K, Saritas T, Uchida S, Kahl T, Borowski T, Paliege A, Bohlick A, Bleich M, Shan Q, Bachmann S (2010) Short-term stimulation of the thiazide-sensitive Na?-Cl- cotransporter by vasopressin involves phosphorylation and membrane translocation. Am J Physiol Renal Physiol 298:F502-F509
43. Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (1998) Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res 5:277-286 (Pubitemid 128670166)
44. Nielsen S, Frokiaer J, Marples D, Kwon TH, Agre P, Knepper MA (2002) Aquaporins in the kidney: from molecules to medicine. Physiol Rev 82:205-244 (Pubitemid 34654219)
45. Ohse T, Pippin JW, Chang AM, Krofft RD, Miner JH, Vaughan MR, Shankland SJ (2009) The enigmatic parietal epithelial cell is finally getting noticed: a review. Kidney Int 76:1225-1238
46. Pradervand S, Zuber Mercier A, Centeno G, Bonny O, Firsov D (2010) A comprehensive analysis of gene expression profiles in distal parts of the mouse renal tubule. Pflugers Arch 460:925- 952
47. Reilly RF, Ellison DH (2000) Mammalian distal tubule: physiology, pathophysiology, and molecular anatomy. Physiol Rev 80:277- 313 (Pubitemid 30060566)
48. Ross BD, Espinal J, Silva P (1986) Glucose metabolism in renal tubular function. Kidney Int 29:54-67 (Pubitemid 16165680)
49. Sabolic I, Valenti G, Verbavatz JM, Van Hoek AN, Verkman AS, Ausiello DA, Brown D (1992) Localization of the CHIP28 water channel in rat kidney. Am J Physiol 263:C1225-C1233 (Pubitemid 23024428)
50. Sandberg MB, Riquier AD, Pihakaski-Maunsbach K, McDonough AA, Maunsbach AB (2007) ANG II provokes acute trafficking of distal tubule Na?-Cl(-) cotransporter to apical membrane. Am J Physiol Renal Physiol 293:F662-F669 (Pubitemid 47403333)
51. Sano H, Kane S, Sano E, Miinea CP, Asara JM, Lane WS, Garner CW, Lienhard GE (2003) Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation. J Biol Chem 278:14599-14602 (Pubitemid 36799780)
52. Sano H, Roach WG, Peck GR, Fukuda M, Lienhard GE (2008) Rab10 in insulin-stimulated GLUT4 translocation. Biochem J 411:89-95 (Pubitemid 351482350)
53. Schmitt R, Ellison DH, Farman N, Rossier BC, Reilly RF, Reeves WB, Oberbaumer I, Tapp R, Bachmann S (1999) Developmental expression of sodium entry pathways in rat nephron. Am J Physiol 276:F367-F381 (Pubitemid 29157529)
54. Stenmark H, Olkkonen VM (2001) The Rab GTPase family. Genome Biol 2:REVIEWS3007
55. Takai Y, Sasaki T, Matozaki T (2001) Small GTP-binding proteins. Physiol Rev 81:153-208 (Pubitemid 32098004)
56. Uchida S, Sasaki S, Nitta K, Uchida K, Horita S, Nihei H, Marumo F (1995) Localization and functional characterization of rat kidney-specific chloride channel, ClC-K1. J Clin Invest 95:104-113
57. Wade JB, Lee AJ, Liu J, Ecelbarger CA, Mitchell C, Bradford AD, Terris J, Kim GH, Knepper MA (2000) UT-A2: a 55 kDa urea transporter in thin descending limb whose abundance is regulated by vasopressin. Am J Physiol Renal Physiol 278:F52-F62 (Pubitemid 30106125)
58. Wagner CA, Finberg KE, Breton S, Marshansky V, Brown D, Geibel JP (2004) Renal vacuolar H?-ATPase. Physiol Rev 84:1263- 1314
59. Wagner CA, Loffing-Cueni D, Yan Q, Schulz N, Fakitsas P, Carrel M, Wang T, Verrey F, Geibel JP, Giebisch G, Hebert SC, Loffing J (2008) Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins. Am J Physiol Renal Physiol 294:F1373-F1380
60. Werner M, Von Wasielewski R, Komminoth P (1996) Antigen retrieval, signal amplification and intensification in immunohistochemistry. Histochem Cell Biol 105:253-260 (Pubitemid 26114785)
61. White RA, Pasztor LM, Richardson PM, Zon LI (2000) The gene encoding TBC1D1 with homology to the tre-2/USP6 oncogene, BUB2, and cdc16 maps to mouse chromosome 5 and human chromosome 4. Cytogenet Cell Genet 89:272-275