Mimicking the tumour microenvironment: Three different co-culture systems induce a similar phenotype but distinct proliferative signals in primary chronic lymphocytic leukaemia cells

British Journal of Haematology

Volumn 158, Issue 5, 2012, Pages 589-599

  Hamilton, Emma ^a   Pearce, Laurence ^b   Morgan, Liam ^b   Robinson, Sophie ^b   Ware, Vicki ^b   Brennan, Paul ^b   Thomas, N Shaun B ^a   Yallop, Deborah ^a   Devereux, Stephen ^a   Fegan, Chris ^b   Buggins, Andrea G S ^a   Pepper, Chris ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Chronic lymphocytic leukaemia; Co culture systems; Microenvironment; Proliferation; Survival

Indexed keywords

ALPHA4 INTEGRIN; CD31 ANTIGEN; CD38 ANTIGEN; CD40 LIGAND; CD69 ANTIGEN; HERMES ANTIGEN; PROTEIN KINASE ZAP 70;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL ACTIVATION; CELL INTERACTION; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERMETHOD COMPARISON; LYMPH NODE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

ANIMALS; ANTIGENS, CD; CELL COMMUNICATION; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LEUKOCYTES, MONONUCLEAR; MICE; MICROVESSELS; PHENOTYPE; TRANSFECTION; TUMOR MICROENVIRONMENT;

EID: 84865108469     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2012.09191.x     Document Type: Article

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