Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Haddad, Dana ^a,b   Chen, Chun Hao ^a   Carlin, Sean ^a   Silberhumer, Gerd ^a   Chen, Nanhai G ^c,d   Zhang, Qian ^c   Longo, Valerie ^a   Carpenter, Susanne G ^a   Mittra, Arjun ^a   Carson, Joshua ^a   Au, Joyce ^a   Gonen, Mithat ^a   Zanzonico, Pat B ^a   Szalay, Aladar A ^b,c,d   Fong, Yuman ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c GENELUX CORPORATION   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; GLV 1H153; GLV 1H68; GREEN FLUORESCENT PROTEIN; IODINE 124; IODINE 131; ONCOLYTIC VIRUS; SODIUM IODIDE SYMPORTER; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG SAFETY; DRUG UPTAKE; GAMMA SCINTIGRAPHY; GENE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMAGING; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR TRANSPORT; MALE; MOUSE; NONHUMAN; ONCOLYTIC VIROTHERAPY; OPTICAL IMAGING; PANCREAS CARCINOMA; PERSISTENT VIRUS INFECTION; PLAQUE FORMING CELL; POSITRON EMISSION TOMOGRAPHY; SINGLE DRUG DOSE; SODIUM IODIDE SYMPORTER GENE; TISSUE DISTRIBUTION; TUMOR XENOGRAFT; VIRAL CLEARANCE; VIRUS REPLICATION;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; IODINE RADIOISOTOPES; MALE; MICE; MOLECULAR IMAGING; ONCOLYTIC VIRUSES; OPTICAL IMAGING; PANCREATIC NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; SYMPORTERS; TIME FACTORS; TISSUE DISTRIBUTION; VACCINIA VIRUS; VIRUS REPLICATION;

EID: 84865077277     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041647     Document Type: Article

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