메뉴 건너뛰기




Volumn 94, Issue 8, 2012, Pages 599-606

Newer anticonvulsants: Lamotrigine, topiramate and gabapentin

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; GABAPENTIN; LAMOTRIGINE; PHENOBARBITAL; PHENTERMINE PLUS TOPIRAMATE; PHENYTOIN; TOPIRAMATE; VALPROIC ACID;

EID: 84865077053     PISSN: 15420752     EISSN: 15420760     Source Type: Journal    
DOI: 10.1002/bdra.23028     Document Type: Article
Times cited : (54)

References (51)
  • 1
    • 77956360935 scopus 로고    scopus 로고
    • A comparison of the pharmacokinetics and pharmacodynamics of pregabalin and gabapentin
    • Bockbrader HN, Wesche D, Miller R, et al. 2010. A comparison of the pharmacokinetics and pharmacodynamics of pregabalin and gabapentin. Clin Pharmacokinet 49: 661-669.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 661-669
    • Bockbrader, H.N.1    Wesche, D.2    Miller, R.3
  • 2
    • 79959829974 scopus 로고    scopus 로고
    • Obstetric outcome in women with epilepsy: a hospital-based, retrospective study
    • Borthen I, Eide MG, Daltveit AK, Gilhus NE. 2011. Obstetric outcome in women with epilepsy: a hospital-based, retrospective study. BJOG 118: 956-965.
    • (2011) BJOG , vol.118 , pp. 956-965
    • Borthen, I.1    Eide, M.G.2    Daltveit, A.K.3    Gilhus, N.E.4
  • 3
    • 79959818305 scopus 로고    scopus 로고
    • Neurodevelopement of children exposed in utero tolomotrigine, sodium valproate and carbamazepine
    • Cummings, C. Stewart M, Stevenson M, et al., 2011. Neurodevelopement of children exposed in utero tolomotrigine, sodium valproate and carbamazepine Arc Dis Child 96:643-647.
    • (2011) Arc Dis Child , vol.96 , pp. 643-647
    • Cummings, C.1    Stewart, M.2    Stevenson, M.3
  • 4
    • 15244362235 scopus 로고    scopus 로고
    • Lamotrigine and the risk of malformations in pregnancy
    • International Lamotrigine Pregnancy Registry Scientific Advisory Committee.
    • Cunnington M, Tennis P; International Lamotrigine Pregnancy Registry Scientific Advisory Committee. 2005. Lamotrigine and the risk of malformations in pregnancy. Neurology 64: 955-960.
    • (2005) Neurology , vol.64 , pp. 955-960
    • Cunnington, M.1    Tennis, P.2
  • 5
    • 84856388467 scopus 로고    scopus 로고
    • Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study
    • Garvey WT, Ryan DH, Look M, et al. 2012. Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study. Am J Clin Nutr 95: 297-308.
    • (2012) Am J Clin Nutr , vol.95 , pp. 297-308
    • Garvey, W.T.1    Ryan, D.H.2    Look, M.3
  • 6
    • 0032872031 scopus 로고    scopus 로고
    • Topiramate
    • Glauser TA. 1999. Topiramate. Epilepsia 40 Suppl 5: S71-S80.
    • (1999) Epilepsia , vol.5 , Issue.40 SUPPL
    • Glauser, T.A.1
  • 7
    • 77649190607 scopus 로고    scopus 로고
    • Gabapentin use in hyperemesis gravidarum: a pilot study
    • Guttuso TJr, Robinson LK, Amankwah KS. 2010. Gabapentin use in hyperemesis gravidarum: a pilot study. Early Hum Dev 86: 65-66.
    • (2010) Early Hum Dev , vol.86 , pp. 65-66
    • Guttuso Jr, T.1    Robinson, L.K.2    Amankwah, K.S.3
  • 8
    • 66749116216 scopus 로고    scopus 로고
    • Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): obstetrical complications and change in seizure frequency: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society
    • Harden CL, Hopp J, Ting TY, et al. 2009. Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): obstetrical complications and change in seizure frequency: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society. Neurology 73: 126-132.
    • (2009) Neurology , vol.73 , pp. 126-132
    • Harden, C.L.1    Hopp, J.2    Ting, T.Y.3
  • 10
    • 84863633751 scopus 로고    scopus 로고
    • Comparative safety of anticonvulsants during pregnancy
    • Hernandez-Diaz S, Smith CR, Shen A, et al. 2012. Comparative safety of anticonvulsants during pregnancy. Neurology 18:1692-1699.
    • (2012) Neurology , vol.18 , pp. 1692-1699
    • Hernandez-Diaz, S.1    Smith, C.R.2    Shen, A.3
  • 12
    • 45949086800 scopus 로고    scopus 로고
    • Increased frequency of isolated cleft palate in infants exposed to lamotrigine during pregnancy
    • Holmes LB, Baldwin EJ, Smith CR, et al. 2008. Increased frequency of isolated cleft palate in infants exposed to lamotrigine during pregnancy. Neurology 70(22 Pt 2 ): 2152-2158.
    • (2008) Neurology , vol.70 , Issue.22 PART 2 , pp. 2152-2158
    • Holmes, L.B.1    Baldwin, E.J.2    Smith, C.R.3
  • 13
    • 11844301288 scopus 로고    scopus 로고
    • The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs
    • Holmes LB, Coull BA, Dorfman J, Rosenberger PB. 2005. The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs. J Pediatr 146: 118-122.
    • (2005) J Pediatr , vol.146 , pp. 118-122
    • Holmes, L.B.1    Coull, B.A.2    Dorfman, J.3    Rosenberger, P.B.4
  • 14
    • 0035849144 scopus 로고    scopus 로고
    • The teratogenicity of anticonvulsant drugs
    • Holmes LB, Harvey EA, Coull BA, et al. 2001. The teratogenicity of anticonvulsant drugs. N Engl J Med 344: 1132-1138.
    • (2001) N Engl J Med , vol.344 , pp. 1132-1138
    • Holmes, L.B.1    Harvey, E.A.2    Coull, B.A.3
  • 15
    • 80053895169 scopus 로고    scopus 로고
    • Fetal effects of anticonvulsant polytherapies: different risks from different drug combinations
    • Holmes LB, Mittendorf R, Shen A, et al. 2011. Fetal effects of anticonvulsant polytherapies: different risks from different drug combinations. Arch Neurol 68: 1275-1281.
    • (2011) Arch Neurol , vol.68 , pp. 1275-1281
    • Holmes, L.B.1    Mittendorf, R.2    Shen, A.3
  • 16
    • 0032806414 scopus 로고    scopus 로고
    • Evaluation of selected characteristics of pregnancy drug registries
    • Honein MA, Paulozzi LJ, Cragan JD, Correa A. 1999. Evaluation of selected characteristics of pregnancy drug registries. Teratology 60: 356-364.
    • (1999) Teratology , vol.60 , pp. 356-364
    • Honein, M.A.1    Paulozzi, L.J.2    Cragan, J.D.3    Correa, A.4
  • 17
    • 50549083309 scopus 로고    scopus 로고
    • Topiramate in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register
    • Hunt S, Russell A, Smithson WH, et al. 2008. Topiramate in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register. Neurology 71: 272-276.
    • (2008) Neurology , vol.71 , pp. 272-276
    • Hunt, S.1    Russell, A.2    Smithson, W.H.3
  • 18
    • 67650403482 scopus 로고    scopus 로고
    • Increased frequency of isolated cleft palate in infants exposed to lamotrigine during pregnancy
    • author reply 1108-.
    • Hunt SJ, Craig JJ, Morrow JI. 2009. Increased frequency of isolated cleft palate in infants exposed to lamotrigine during pregnancy. Neurology 72: 1108; author reply 1108-1109.
    • (2009) Neurology , vol.72 , pp. 1108-1109
    • Hunt, S.J.1    Craig, J.J.2    Morrow, J.I.3
  • 19
    • 74949138710 scopus 로고    scopus 로고
    • Drug interactions involving the new second- and third-generation antiepileptic drugs
    • Johannessen Landmark C, Patsalos PN. 2010. Drug interactions involving the new second- and third-generation antiepileptic drugs. Expert Rev Neurother 10: 119-140.
    • (2010) Expert Rev Neurother , vol.10 , pp. 119-140
    • Johannessen Landmark, C.1    Patsalos, P.N.2
  • 20
    • 33750366552 scopus 로고    scopus 로고
    • Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?
    • Johannessen SI, Tomson T. 2006. Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed? Clin Pharmacokinet 45: 1061-1075.
    • (2006) Clin Pharmacokinet , vol.45 , pp. 1061-1075
    • Johannessen, S.I.1    Tomson, T.2
  • 21
    • 23644441735 scopus 로고    scopus 로고
    • Treatment of epilepsy in adults: expert opinion, 2005
    • quiz S65-67.
    • Karceski S, Morrell MJ, Carpenter D. 2005. Treatment of epilepsy in adults: expert opinion, 2005. Epilepsy Behav 7 Suppl 1: S1-S64; quiz S65-67.
    • (2005) Epilepsy Behav , vol.7 , Issue.SUPPL 1 , pp. 1-64
    • Karceski, S.1    Morrell, M.J.2    Carpenter, D.3
  • 22
    • 73349117801 scopus 로고    scopus 로고
    • Obstetric outcomes in women with multiple sclerosis and epilepsy
    • Kelly VM, Nelson LM, Chakravarty EF. 2009. Obstetric outcomes in women with multiple sclerosis and epilepsy. Neurology 73: 1831-1836.
    • (2009) Neurology , vol.73 , pp. 1831-1836
    • Kelly, V.M.1    Nelson, L.M.2    Chakravarty, E.F.3
  • 23
    • 79957965479 scopus 로고    scopus 로고
    • Prescription patterns of antiepileptic drugs in patients with epilepsy in a nation-wide population
    • Landmark CJ, Fossmark H, Larsson PG, et al. 2011. Prescription patterns of antiepileptic drugs in patients with epilepsy in a nation-wide population. Epilepsy Res 95: 51-59.
    • (2011) Epilepsy Res , vol.95 , pp. 51-59
    • Landmark, C.J.1    Fossmark, H.2    Larsson, P.G.3
  • 24
    • 0022900644 scopus 로고
    • Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action
    • Leach MJ, Marden CM, Miller AA. 1986. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia 27: 490-497.
    • (1986) Epilepsia , vol.27 , pp. 490-497
    • Leach, M.J.1    Marden, C.M.2    Miller, A.A.3
  • 26
    • 0036905381 scopus 로고    scopus 로고
    • Outcome of pregnancy in women attending an outpatient epilepsy clinic: adverse features associated with higher doses of sodium valproate
    • Mawer G, Clayton-Smith J, Coyle H, Kini U. 2002. Outcome of pregnancy in women attending an outpatient epilepsy clinic: adverse features associated with higher doses of sodium valproate. Seizure 11: 512-518.
    • (2002) Seizure , vol.11 , pp. 512-518
    • Mawer, G.1    Clayton-Smith, J.2    Coyle, H.3    Kini, U.4
  • 27
    • 64749112939 scopus 로고    scopus 로고
    • Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs
    • Meador KJ, Baker GA, Browning N, et al. 2009. Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. N Engl J Med 360: 1597-1605.
    • (2009) N Engl J Med , vol.360 , pp. 1597-1605
    • Meador, K.J.1    Baker, G.A.2    Browning, N.3
  • 28
    • 79551710618 scopus 로고    scopus 로고
    • Foetal antiepileptic drug exposure and verbal versus non-verbal abilities at three years of age
    • Meador KJ, Baker GA, Browning N, et al. 2011. Foetal antiepileptic drug exposure and verbal versus non-verbal abilities at three years of age. Brain 134(Pt 2): 396-404.
    • (2011) Brain , vol.134 , Issue.PART 2 , pp. 396-404
    • Meador, K.J.1    Baker, G.A.2    Browning, N.3
  • 29
    • 79956098246 scopus 로고    scopus 로고
    • Newer-generation antiepileptic drugs and the risk of major birth defects
    • Mølgaard-Nielsen D, Hviid A. 2011. Newer-generation antiepileptic drugs and the risk of major birth defects. JAMA 305: 1996-2002.
    • (2011) JAMA , vol.305 , pp. 1996-2002
    • Mølgaard-Nielsen, D.1    Hviid, A.2
  • 30
    • 0141706894 scopus 로고    scopus 로고
    • Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry
    • Montouris G. 2003. Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry. Epilepsy Behav 4: 310-317.
    • (2003) Epilepsy Behav , vol.4 , pp. 310-317
    • Montouris, G.1
  • 31
    • 0033934755 scopus 로고    scopus 로고
    • A clinical study of 57 children with fetal anticonvulsant syndromes
    • Moore SJ, Turnpenny P, Quinn A, et al. 2000. A clinical study of 57 children with fetal anticonvulsant syndromes. J Med Genet 37: 489-497.
    • (2000) J Med Genet , vol.37 , pp. 489-497
    • Moore, S.J.1    Turnpenny, P.2    Quinn, A.3
  • 32
    • 32344440085 scopus 로고    scopus 로고
    • Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register
    • Morrow J, Russell A, Guthrie E, et al. 2006. Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry 77: 193-198.
    • (2006) J Neurol Neurosurg Psychiatry , vol.77 , pp. 193-198
    • Morrow, J.1    Russell, A.2    Guthrie, E.3
  • 33
    • 79952024499 scopus 로고    scopus 로고
    • Language skills of school-aged Children prenatally exposed to antiepileptic drugs
    • Nadelbaum C, Anderson VA, Vadja F, et al. 2011. Language skills of school-aged Children prenatally exposed to antiepileptic drugs. Neurology 76:719-726.
    • (2011) Neurology , vol.76 , pp. 719-726
    • Nadelbaum, C.1    Anderson, V.A.2    Vadja, F.3
  • 34
    • 0024533230 scopus 로고
    • Malformations due to presumed spontaneous mutations in newborn infants
    • Nelson K, Holmes LB. 1989. Malformations due to presumed spontaneous mutations in newborn infants. N Engl J Med 320: 19-23.
    • (1989) N Engl J Med , vol.320 , pp. 19-23
    • Nelson, K.1    Holmes, L.B.2
  • 35
    • 44849083542 scopus 로고    scopus 로고
    • Plasma concentrations of lamotrigine and its 2-N-glucuronide metabolite during pregnancy in women with epilepsy
    • Ohman I, Beck O, Vitols S, Tomson T. 2008. Plasma concentrations of lamotrigine and its 2-N-glucuronide metabolite during pregnancy in women with epilepsy. Epilepsia 49: 1075-1080.
    • (2008) Epilepsia , vol.49 , pp. 1075-1080
    • Ohman, I.1    Beck, O.2    Vitols, S.3    Tomson, T.4
  • 36
    • 0030299983 scopus 로고    scopus 로고
    • Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy
    • Ornoy A, Cohen E. 1996. Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy. Arch Dis Child 75: 517-520.
    • (1996) Arch Dis Child , vol.75 , pp. 517-520
    • Ornoy, A.1    Cohen, E.2
  • 37
    • 44149124250 scopus 로고    scopus 로고
    • The outcome of pregnancy following topiramate treatment: a study on 52 pregnancies
    • Ornoy A, Zvi N, Arnon J, et al. 2008. The outcome of pregnancy following topiramate treatment: a study on 52 pregnancies. Reprod Toxicol 25: 388-389.
    • (2008) Reprod Toxicol , vol.25 , pp. 388-389
    • Ornoy, A.1    Zvi, N.2    Arnon, J.3
  • 38
    • 0038282941 scopus 로고    scopus 로고
    • Craniofacial skeletal deviations following in utero exposure to the anticonvulsant phenytoin: monotherapy and polytherapy
    • Orup HIJr, Holmes LB, Keith DA, Coull BA. 2003. Craniofacial skeletal deviations following in utero exposure to the anticonvulsant phenytoin: monotherapy and polytherapy. Orthod Craniofac Res 6: 2-19.
    • (2003) Orthod Craniofac Res , vol.6 , pp. 2-19
    • Orup Jr, H.I.1    Holmes, L.B.2    Keith, D.A.3    Coull, B.A.4
  • 39
    • 0141542598 scopus 로고    scopus 로고
    • Antiepileptic drug pharmacokinetics during pregnancy and lactation
    • Pennell PB. 2003. Antiepileptic drug pharmacokinetics during pregnancy and lactation. Neurology 61(6 Suppl 2 ): S35-S42.
    • (2003) Neurology , vol.61 , Issue.6 SUPPL 2
    • Pennell, P.B.1
  • 40
    • 77957174599 scopus 로고
    • Developmental toxicity studies in mice, rats and rabbits with the anticonvulsant gabapentin
    • Petrere JA, Andreson JA. 1994. Developmental toxicity studies in mice, rats and rabbits with the anticonvulsant gabapentin. Fund Appl Toxicology 23:585-589.
    • (1994) Fund Appl Toxicology , vol.23 , pp. 585-589
    • Petrere, J.A.1    Andreson, J.A.2
  • 41
    • 39049124555 scopus 로고    scopus 로고
    • Teratogenic effects of the anticonvulsant gabapentin in mice
    • Prakash, Prabha LV, Rai R, et al., 2008. Teratogenic effects of the anticonvulsant gabapentin in mice. Sing Med J 49:47-53.
    • (2008) Sing Med J , vol.49 , pp. 47-53
    • Prakash Prabha, L.V.1    Rai, R.2
  • 42
    • 79955524916 scopus 로고    scopus 로고
    • Lamotrigine and its N2-glucuronide during pregnancy: the significance of renal clearance and estradiol
    • Epub ahead of print].
    • Reimers A, Helde G, Bråthen G, Brodtkorb E. 2011. Lamotrigine and its N2-glucuronide during pregnancy: the significance of renal clearance and estradiol. Epilepsy Res [Epub ahead of print].
    • (2011) Epilepsy Res
    • Reimers, A.1    Helde, G.2    Bråthen, G.3    Brodtkorb, E.4
  • 43
    • 0003898553 scopus 로고
    • Bethesda, Maryland: U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health. NIH Publication No. 79-1649.
    • Rothman KJ, Boice JDJr. 1979. Epidemiologic analysis with a programmable calculator. Bethesda, Maryland: U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health. NIH Publication No. 79-1649.
    • (1979) Epidemiologic analysis with a programmable calculator
    • Rothman, K.J.1    Boice Jr, J.D.2
  • 44
    • 0032747235 scopus 로고    scopus 로고
    • Antiepileptic drug regimens and major congenital abnormalities in the offspring
    • Samrén EB, van Duijn CM, Christiaens GC, et al. 1999. Antiepileptic drug regimens and major congenital abnormalities in the offspring. Ann Neurol 46: 739-746.
    • (1999) Ann Neurol , vol.46 , pp. 739-746
    • Samrén, E.B.1    van Duijn, C.M.2    Christiaens, G.C.3
  • 45
    • 33947223462 scopus 로고    scopus 로고
    • Pharmacokinetics and therapeutic drug monitoring of newer antiepileptic drugs during pregnancy and the puerperium
    • Tomson T, Battino D. 2007. Pharmacokinetics and therapeutic drug monitoring of newer antiepileptic drugs during pregnancy and the puerperium. Clin Pharmacokinet 46: 209-219.
    • (2007) Clin Pharmacokinet , vol.46 , pp. 209-219
    • Tomson, T.1    Battino, D.2
  • 46
    • 77951527560 scopus 로고    scopus 로고
    • Pregnancy registries: differences, similarities, and possible harmonization
    • Tomson T, Battino D, Craig J, et al. 2010. Pregnancy registries: differences, similarities, and possible harmonization. Epilepsia 51: 909-915.
    • (2010) Epilepsia , vol.51 , pp. 909-915
    • Tomson, T.1    Battino, D.2    Craig, J.3
  • 47
    • 79958781995 scopus 로고    scopus 로고
    • Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry
    • Tomson T, Battino D, Bonizzoni E, et al. 2011. Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry. Lancet Neurol 10: 609-617.
    • (2011) Lancet Neurol , vol.10 , pp. 609-617
    • Tomson, T.1    Battino, D.2    Bonizzoni, E.3
  • 48
    • 35948953277 scopus 로고    scopus 로고
    • The Australian Register of Antiepileptic Drugs in Pregnancy: the first 1002 pregnancies
    • Vajda FJE, Hitchcock A, Graham J, et al. 2007. The Australian Register of Antiepileptic Drugs in Pregnancy: the first 1002 pregnancies. Aust N Z J Obstet Gynecol 47: 468-474.
    • (2007) Aust N Z J Obstet Gynecol , vol.47 , pp. 468-474
    • Vajda, F.J.E.1    Hitchcock, A.2    Graham, J.3
  • 49
    • 84855193549 scopus 로고    scopus 로고
    • Teratogenicity of the newer antiepileptic drugs-the Australian experience
    • Vajda FJ, Graham J, Rosen A, et al. 2012. Teratogenicity of the newer antiepileptic drugs-the Australian experience. J Clin Neurosci 19: 57-59.
    • (2012) J Clin Neurosci , vol.19 , pp. 57-59
    • Vajda, F.J.1    Graham, J.2    Rosen, A.3
  • 50
    • 69149088182 scopus 로고    scopus 로고
    • Pregnancy, delivery, and outcome for the child in maternal epilepsy
    • Veiby G, Daltveit AK, Engelsen BA, Gilhus NE. 2009. Pregnancy, delivery, and outcome for the child in maternal epilepsy. Epilepsia 50: 2130-2139.
    • (2009) Epilepsia , vol.50 , pp. 2130-2139
    • Veiby, G.1    Daltveit, A.K.2    Engelsen, B.A.3    Gilhus, N.E.4
  • 51
    • 1242314854 scopus 로고    scopus 로고
    • Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study
    • Wide K, Winbladh B, Källén B. 2004. Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study. Acta Paediatr 93: 174-176.
    • (2004) Acta Paediatr , vol.93 , pp. 174-176
    • Wide, K.1    Winbladh, B.2    Källén, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.