Plasma concentrations of lamotrigine and its 2-N-glucuronide metabolite during pregnancy in women with epilepsy

Epilepsia

Volumn 49, Issue 6, 2008, Pages 1075-1080

  Öhman, Inger ^a,b   Beck, Olof ^a   Vitols, Sigurd ^a   Tomson, Torbjörn ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Epilepsy; Glucuronidation; Lamotrigine; Pharmacokinetics; Pregnancy

Indexed keywords

CLONAZEPAM; DRUG METABOLITE; LAMOTRIGINE; LAMOTRIGINE 2 N GLUCURONIDE; TOPIRAMATE;

ADULT; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSE INCREASE; EPILEPSY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MONOTHERAPY; PREGNANT WOMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; THIRD TRIMESTER PREGNANCY;

ADOLESCENT; ADULT; ANTICONVULSANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; EPILEPSY; FEMALE; HUMANS; METABOLIC CLEARANCE RATE; METABOLIC DETOXICATION, DRUG; MIDDLE AGED; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY TRIMESTERS; REFERENCE VALUES; TRIAZINES;

EID: 44849083542     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2007.01471.x     Document Type: Article

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